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Inventor:
Boehm; Jeffrey Charles
Address:
King of Prussia, PA
No. of patents:
15
Patents:












Patent Number Title Of Patent Date Issued
8071584 Indole carboxamides as IKK2 inhibitors December 6, 2011
The invention is directed to novel indole carboxamide derivatives. Specifically, the invention is directed to compounds according to formula (I): ##STR00001## wherein R1, R2, R3, R4, and m are as defined herein. The compounds of the invention are inhibitors of IKK2 and can be useful
7550480 Compounds June 23, 2009
Novel substituted 1,5,7-trisubstituted-1,8-napthyridin-2(1H)-one compounds; 1,5,7 trisubstituted-1,6-napthyridine-2-(1H)-one compounds and 1,5,7-trisubstituted quinoline-2(1H)-one compounds, processes for the preparation thereof, the use thereof in treating CSBP/p38 kinase mediated d
6730683 Compounds of heteroaryl substituted imidazole, their pharmaceutical compositions and uses May 4, 2004
Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
6369068 Amino substituted pyrimidine containing compounds April 9, 2002
Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
6335340 compounds of heteroaryl substituted imidazole, their pharmaceutical compositons and uses January 1, 2002
Compounds of 1,4,5-substituted imidazole wherein one of the substituents can be a substituted pyrimidine, pyridazine or 1,2,4-triazine. These compounds and their pharmaceutical compositions are used in treating cytokine mediated diseases by inhibiting the production of IL-1 (interleu
6288062 Oxazoles for treating cytokine mediated diseases September 11, 2001
This invention relates to the novel oxazole compounds of Formula (I) and novel pharmaceutical compositions comprising a compound of Formula (I) and a pharmaceutically acceptable diluent or carrier. This invention also relates to a method of inhibiting cytokines and the treatment of cytok
6251914 Cycloalkyl substituted imidazoles June 26, 2001
Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy.
6218537 Process for making pyridyl and pyrimidine substituted imidazole compounds April 17, 2001
1,4,5,-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
6150557 Compounds November 21, 2000
Novel 1, 4, 5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
6103936 Process of making tosylbenzyl formamide derivatives August 15, 2000
The present invention is to a novel process for the preparation of a compound of the formula: ##STR1## wherein p is 0, or 2;Ar is an optionally substituted phenyl or naphtyl; andinter alia R4 is an optionally susbtituted phenyl, naphth-1-yl, naphth-2-yl, or a heteroaryl ring;which pr
5969184 Amide compounds October 19, 1999
The present invention is directed to the novel intermediate compounds of the formula: ##STR1## wherein, interalia, R.sub.4 is a substituted phenyl or an optionally substituted napthyl derivative.
5869660 Process of preparing imidazole compounds February 9, 1999
Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
5739143 Imidazole compounds and compositions April 14, 1998
Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
5670527 Pyridyl imidazole compounds and compositions September 23, 1997
Novel 1, 4, 5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
5658903 Imidazole compounds, compositions and use August 19, 1997
Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.










 
 
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