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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Blau; Helen M.
Address:
Menlo Park, CA
No. of patents:
7
Patents:












Patent Number Title Of Patent Date Issued
8586294 Detection of protein translocation by beta-galactosidase reporter fragment complementation November 19, 2013
Methods and compositions are provided for detecting molecular translocations, particularly protein translocations within and between subcellular copartments, using at least two components that exhibit a localization-dependent difference in complementation activity. In particular, alp
8148110 Detection of molecular interactions by .beta.-lactamase reporter fragment complementation April 3, 2012
Methods and compositions for detecting molecular interactions, particularly protein-protein interactions, using at least two inactive, weakly-complementing .beta.-lactamase fragments are provided. The invention allows detection of such interactions in eukaryotic and mammalian cells,
7582417 Sequential reporter enzyme luminescence (SRL) methods and compositions for practicing the same September 1, 2009
Sequential reporter enzyme luminescence (SRL) methods are provided. In the subject methods, the activity of a reporter enzyme is evaluated using a secondary reporter system that employs a product of a reporter enzyme mediated reaction as a luminescent substrate, e.g., luciferase substrat
7223537 Detection of molecular interactions by reporter subunit complementation May 29, 2007
Methods and compositions for detecting molecular interactions, particularly protein-protein interactions, are provided. The invention allows detection of such interactions in living cells or in vitro. Detection of molecular interactions in living cells is not limited to the nuclear c
6342345 Detection of molecular interactions by reporter subunit complementation January 29, 2002
Methods and compositions for detecting molecular interactions, particularly protein-protein interactions, are provided. The invention allows detection of such interactions in living cells or in vitro. Detection of molecular interactions in living cells is not limited to the nuclear compa
5538722 Isolation, growth, differentiation and genetic engineering of human muscle cells July 23, 1996
Myoblasts are produced, conveniently in low or serum-free medium, for use in introduction into a mammalian host, particularly a human host, for treatment of diseases of muscle tissue or acting as carriers for genetic capabilities, particularly correcting a genetic defect or for productio
5538722 Isolation, growth, differentiation and genetic engineering of human muscle cells July 23, 1996
Myoblasts are produced, conveniently in low or serum-free medium, for use in introduction into a mammalian host, particularly a human host, for treatment of diseases of muscle tissue or acting as carriers for genetic capabilities, particularly correcting a genetic defect or for productio










 
 
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