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Bingle; Wade H.
Vancouver, CA
No. of patents:

Patent Number Title Of Patent Date Issued
7270993 Protease deficient Caulobacter host cells September 18, 2007
Caulobacter optimized for use in expression of heterologous peptides as part of a hybrid Caulobacter S-layer protein are provided as well as methods for producing such Caulobacter. Caulobacter of this invention are deficient in a native Caulobacter protease that cleaves hybrid S-layer
6210948 Expression and secretion of heterologous polypeptides from caulobacter April 3, 2001
DNA constructs are provided which code for a chimeric protein in which the C-terminal region corresponds to the extreme C-terminal amino acids of a Caulobacter S-layer protein, fused with a heterologous polypeptide. Bacterial cells containing the DNA constructs, or which express the DNA
5976864 Expression and secretion of heterologous polypeptides from caulobacter November 2, 1999
DNA constructs are provided which code for at least the extreme C-terminal amino acids of the rsaA protein of Caulobacter crescentus fused with heterologous polypeptides. Baterial cells containing, or which express the DNA constructs and secrete the resulting protein are also provided.
5500353 Bacterial surface protein expression March 19, 1996
This invention provides a bacterium having an S-layer modified such that the bacterium S-layer protein gene contains one or more in-frame sequences coding for one or more heterologous polypeptides and, the S-layer is a fusion product of the S-layer protein and the heterologous polypeptid

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