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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Bernardon; Jean-Michel
Address:
Le Rouret, FR
No. of patents:
53
Patents:


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Patent Number Title Of Patent Date Issued
RE37947 Aromatic polyenic compounds and pharmaceutical/cosmetic compositions comprised thereof December 31, 2002
Novel pharmaceutically/cosmetically-active aromatic polyenic compounds have the structural formula (I): ##STR1##and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular, bone
7148245 Biphenyl derivatives substituted with an aromatic or heteroaromatic radical, and pharmaceutical December 12, 2006
Compounds of formula (I): ##STR00001## in which: Ar represents an aromatic or a heteroaromatic radical optionally substituted, in particular, with an alkyl or a carboxyl group, R.sub.2 and R.sub.3 represent, in particular, H or alkyl, or R.sub.2 and R.sub.3, taken together, form a
6924388 Bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof August 2, 2005
Novel pharmaceutically/cosmetically-active bicyclic aromatic compounds having the structural formula (I): ##STR1##in which Ar.sub.1 is a radical having one of the structural formulae (a)-(c): ##STR2##and Ar.sub.2, X.sub.1, R.sup.1, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.s
6921777 Heteroethynylenic compounds and pharmaceutical and cosmetic compositions containing them July 26, 2005
The invention relates to novel heteroethynylenic compounds having the general formula (I): ##STR1##as well as to the use of these compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, respiratory, cardiovascular and opht
6849658 Biaromatic compounds and pharmaceutical and cosmetic compositions comprising them February 1, 2005
The invention concerns bi-aromatic compounds of formula (I) in which Ar represents (a), Z being O or S, R.sub.1 is CH.sub.3, --CH.sub.2 --O--R.sub.6, --OR.sub.6 or --COR.sub.7 ; R.sub.2 is --OR.sub.8, --SR.sub.8 or a polyether radical if in the latter case R.sub.4 is C.sub.1 -C.sub.2
6825360 Bicyclic aromatic compounds November 30, 2004
The invention relates to novel bicyclic aromatic compounds which have the general formula (I): ##STR1##as well as to the use of these compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, respiratory, cardiovascular and
6689922 Vitamin D analogues February 10, 2004
The invention concerns novel bi-aromatic compounds having the formula: ##STR1##which are analogs of vitamin D, the process of preparing them, as well as their use in pharmaceutical compositions in human or veterinary medicine, particularly in dermatology, cancer treatment, treatment of a
6649612 Biphenyl derivatives substituted with an aromatic or heteroaromatic radical, and pharmaceutical November 18, 2003
Compounds of formula (I): ##STR1##in which: Ar represents an aromatic or a heteroaromatic radical optionally substituted, in particular, with an alkyl or a carboxyl group, R.sub.2 and R.sub.3 represent, in particular, H or alkyl, or R.sub.2 and R.sub.3, taken together, form a 5- or
6632963 Bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof October 14, 2003
Novel pharmaceutically/cosmetically-active bicyclic aromatic compounds have the structural formula (I): ##STR1##in which Ar.sub.1 is a radical having one of the structural formulae (a)-(c): ##STR2##Ar.sub.2 is a radical having one of the following formulae (d)-(h): ##STR3##and X
6515021 Bicyclic aromatic compounds February 4, 2003
The invention relates to novel bicyclic aromatic compounds which have the general formula (I): ##STR1##as well as to the use of these compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, respiratory, cardiovascular and
6444709 Heteroethylene compounds and pharmaceutical and cosmetic compositions containing same September 3, 2002
The invention relates to novel heteroethynylenic compounds having the general formula (I): ##STR1##as well as to the use of these compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, respiratory, cardiovascular and opht
6441010 Bi-aromatic compounds linked via a heteroethynylene radical, and pharmaceutical and cosmetic com August 27, 2002
Bi-aromatic compounds linked via a heteroethynylene radical are provided along with pharmaceutical and cosmetic compositions containing these compounds and methods for their use.
6368608 Polyaromatic propynyl compounds and pharmaceutical/cosmetic compositions comprised thereof April 9, 2002
Novel pharmaceutically/cosmetically-active polyaromatic propynyl compounds have the structural formula (I): ##STR1##in which X is one of the radicals: ##STR2##and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological
6346546 Biaromatic compounds and pharmaceutical and cosmetic compositions comprising them February 12, 2002
Biaromatic compounds connected by a propynylene or ailenylene bond, corresponding to the formula (I). ##STR1##
6326510 Bi-aromatic compounds, compositions containing them and uses December 4, 2001
The invention relates to novel biaromatic compounds having general formula I ##STR1##and their use in pharmaceutical compositions for use in human and veterinary medicine, in particular for treating dermatological, rheumatic, respiratory, cardiovascular, and ophthalmological disorder
6316009 Biphenyl derivatives substituted by an aromatic or heteroaromatic radical and pharamaceutical an November 13, 2001
"Biphenyl derivatives substituted with an aromatic or heteroaromatic radical, and pharmaceutical and cosmetic compositions containing them" ##STR1##in which:Ar represents an aromatic or a heteroaromatic radical optionally substituted, in particular, with an alkyl or a carboxyl group,R.su
6313162 Propynyl or dienyl biaromatic compounds November 6, 2001
The invention relates to novel propynyl or dienyl biaromatic compounds which have the general formula (I) ##STR1##as well as to the use of these compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, respiratory, cardiova
6258775 Bi-aromatic compounds, pharmaceutical and cosmetic compositions containing same and uses July 10, 2001
The invention relates to novel biaromatic compounds having general formula I ##STR1##and their use in pharmaceutical compositions for use in human and veterinary medicine, in particular for treating dermatological, rheumatic, respiratory, cardiovascular, and ophthalmological disorder
6225328 Adamantyl-substituted retinoids and pharmaceutical/cosmetic compositions comprised thereof May 1, 2001
Pharmaceutically/cosmetically-active adamantyl-substituted retinoid compounds have the structural formula (I): ##STR1##wherein Ar is a radical having one of the formulae (a)-(d): ##STR2##and are useful for the treatment of disorders and/or ailments manifesting an overregulation of PA
6214878 Stilbene compounds comprising an adamantyl group, compositions and methods thereof April 10, 2001
The invention relates to novel stilbene compounds having the general formula (I): ##STR1##as well as to pharmaceutical compositions for use in human or veterinary medicine, including dermatological, rheumatic, respiratory, cardiovascular and ophthalmic conditions and cosmetic composi
6201019 Bi-aromatic compounds bound by a heteroethynylene radical and pharmaceutical and cosmetic compos March 13, 2001
Bi-aromatic compounds linked via a heteroethynylene radical are provided along with pharmaceutical and cosmetic compositions containing these compounds and methods for their use.
6171603 Bioaromatic amido compounds and pharmaceutical/cosmetic compositions comprised thereof January 9, 2001
Novel pharmaceutically/cosmetically-active biaromatic amido compounds have the structural formula (I): ##STR1##in which Ar is a radical selected from among those of the following formulae (a)-(e): ##STR2##and are useful for the treatment of a wide variety of disease states, wheth
6162815 RXR-agonist polycyclic aromatic compounds, pharmaceutical/cosmetic compositions comprising said December 19, 2000
Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds having the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(e): ##STR2## which are useful for the treatment of a wide variety of disease states, whether human or v
6162445 Polyaromatic propynyl compounds and pharmaceutical/cosmetic compositions comprised thereof December 19, 2000
Novel pharmaceutically/cosmetically-active polyaromatic propynyl compounds have the structural formula (I): in which X is one of the radicals: ##STR1## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheum
6156788 Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof December 5, 2000
Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(e): ##STR2## and are useful for the treatment of a wide variety of disease states, whether human or veter
6156750 Bioactive bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof December 5, 2000
Novel pharmaceutically/cosmetically-active bicyclic aromatic compounds have the structural formula (I): ##STR1## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular a
6150413 Triaromatic compounds and pharmaceutical/cosmetic compositions comprised thereof November 21, 2000
Novel pharmaceutically/cosmetically-active triaromatic compounds have the structural formula (I): ##STR1## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular, bone a
6147255 Bicyclic-aromatic compounds November 14, 2000
The invention relates to novel bicyclic aromatic compounds which have the general formula (I): ##STR1## as well as to the use of these compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, respiratory, cardiovascular
6103762 Bi-aromatic compounds and pharmaceutical and cosmetic compositions containing same August 15, 2000
The invention concerns bi-aromatic compounds of formula (I) in which Ar represents (a), Z being O or S, R.sub.1 is --CH.sub.3, --CH.sub.2 --O--R.sub.6, --OR.sub.6 or --COR.sub.7 ; R.sub.2 is --OR.sub.8, --SR.sub.8 or a polyether radical if in the latter case R.sub.4 is C.sub.1 -C.sub
6051243 Polyaromatic amide compounds and pharmaceutical/cosmetic compositions comprised thereof April 18, 2000
Novel pharmaceutically/cosmetically-active polyaromatic amides have the structural formula (I): ##STR1## wherein Z is a radical --CO--NH-- or --NH--CO--,and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological,
6046220 Propynyl or dienyl biaromatic compounds April 4, 2000
The invention relates to novel propynyl or dienyl biaromatic compounds which have the general formula (I) ##STR1## as well as to the use of these compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, respiratory, car
6015569 Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof January 18, 2000
Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(e): ##STR2## and are useful for the treatment of a wide variety of disease states, whether human or veter
5985928 Bioactive bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof November 16, 1999
Novel pharmaceutically/cosmetically-active bicyclic aromatic compounds have the structural formula (I): ##STR1## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular a
5952382 Adamantyl-substituted retinoids and pharmaceutical/cosmetic compositions comprised thereof September 14, 1999
Pharmaceutically/cosmetically-active adamantyl-substituted retinoid compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formula (a) - (d): ##STR2## and are useful for the treatment of disorders and/or ailments manifesting an overregul
5935585 Biaromatic amido compounds and pharmaceutical/cosmetic compositions comprised thereof August 10, 1999
Novel pharmaceutically/cosmetically-active biaromatic amido compounds have the structural formula (I): ##STR1## in which Ar is a radical selected from among those of the following formulae (a)-(e): ##STR2## and are useful for the treatment of a wide variety of disease states,
5877342 Adamantyl-substituted biaromatic compounds and pharmaceutical/cosmetic compositions comprised th March 2, 1999
Novel pharmaceutically/cosmetically-active adamantyl-substituted biaromatic compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a')-(f'): ##STR2## and are useful for the treatment of a wide variety of disease states, whether
5798354 Use of adamantyl-substituted polycyclic acetylene compounds in skin and hair treatment August 25, 1998
Novel pharmaceutically/cosmetically-active adamantyl-substituted polycyclic acetylene compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(f): ##STR2## and are useful for the treatment of a wide variety of disease states,
5786379 Adamantyl-substituted biaromatic compounds and pharmaceutical/cosmetic compositions comprised th July 28, 1998
Novel pharmaceutically/cosmetically-active adamantyl-substituted biaromatic compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a')-(f'): ##STR2## and are useful for the treatment of a wide variety of disease states, whether
5766610 Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof June 16, 1998
Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(e): ##STR2## and are useful for the treatment of a wide variety of disease states, whether human or veter
5763487 Bioactive bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof June 9, 1998
Novel pharmaceutically/cosmetically-active bicyclic aromatic compounds have the structural formula (I): ##STR1## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular a
5723499 Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof March 3, 1998
Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(i): ##STR2## and are useful for the treatment of a wide variety of disease states, whether human or veter
5716624 Polyaromatic propynyl compounds and pharmaceutical/cosmetic compositions comprised thereof February 10, 1998
Novel pharmaceutically/cosmetically-active polyaromatic propynyl compounds have the structural formula (1): ##STR1## in which X is one of the radicals: ##STR2## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example derm
5709867 Polyaromatic amide compounds and pharmaceutical/cosmetic compositions comprised thereof January 20, 1998
Novel pharmaceutically/cosmetically-active polyaromatic amides have the structural formula (I): ##STR1## wherein Z is a radical --CO--NH-- or --NH--CO--, and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological,
5705167 Aromatic polyenic compounds and pharmaceutical/cosmetic compositions comprised thereof January 6, 1998
Novel pharmaceutically/cosmetically-active aromatic polyenic compounds have the structural formula (I): ##STR1## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular,
5654331 Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicin August 5, 1997
Diaromatic compounds, characterised in that they correspond to the following general formula: ##STR1## in which: R.sub.1 is --CH.sub.3, --CH.sub.2 OH, --COR.sub.8 or --CH.sub.2 OCOR.sub.9, R.sub.8 is H, OH, --OR.sub.10, --N(rr') or alkyl, R.sub.10 is alkyl, alkenyl, aryl or aralk
5574036 Adamantyl-substituted polycyclic acetylene compounds and pharmaceutical/cosmetic compositions co November 12, 1996
Novel pharmaceutically/cosmetically-active adamantyl-substituted polycyclic acetylene compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(f): ##STR2## and are useful for the treatment of a wide variety of disease states,
5476860 Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicin December 19, 1995
Diaromatic compounds, characterized in that they correspond to the following general formula: ##STR1## in which: R.sub.1 is --CH.sub.3, --CH.sub.2 OH, --COR.sub.8 or --CH.sub.2 OCOR.sub.9, R.sub.8 is H, OH, --OR.sub.10, --N(rr') or alkyl, R.sub.10 is alkyl, alkenyl, aryl or aralk
5428052 Aromatic heterocyclic derivatives and their therapeutic and cosmetic use June 27, 1995
Aromatic heterocyclic derivatives have the formula ##STR1## wherein R.sub.1 represents (i)--CH.sub.3, (ii)--CH.sub.2 OH or (iii) ##STR2## wherein R.sub.3 represents hydrogen, --OR.sub.4 wherein R.sub.4 represents hydrogen, alkyl having 1-20 carbon atoms or mono- or polyhydroxyalk
5288744 Aromatic heterocyclic derivatives and their therapeutic and cosmetic use February 22, 1994
Aromatic heterocyclic derivatives have the formula ##STR1## wherein R.sub.1 represents (i)--CH.sub.3, (ii)--CH.sub.2 OH or (iii) ##STR2## wherein R.sub.3 represents hydrogen, --OR.sub.4 wherein R.sub.4 represents hydrogen, alkyl having 1-20 carbon atoms or mono- or polyhydroxyalk
5260295 Aromatic heterocyclic derivatives and their therapeutic and cosmetic use November 9, 1993
Aromatic heterocyclic derivatives have the formula ##STR1## wherein R.sub.1 represents (i)--CH.sub.3, (ii)--CH.sub.2 OH or (iii) ##STR2## wherein R.sub.3 represents hydrogen, --OR.sub.4 wherein R.sub.4 represents hydrogen, alkyl having 1-20 carbon atoms or mono- or polyhydroxyalk
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