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Inventor:
Atwell; Graham J.
Address:
Auckland, NZ
No. of patents:
11
Patents:












Patent Number Title Of Patent Date Issued
7776924 Nitroaniline-based alkylating agents and their use as prodrugs August 17, 2010
Nitroaniline-based unsymmetrical mustards of the general formula (I) are provided, together with methods of preparation and methods for their use as prodrugs for gene-dependent enzyme prodrug therapy (GDEPT) and cell ablation therapy in conjunction with nitroreductase enzymes as hypoxia
6130237 Condensed N-aclyindoles as antitumor agents October 10, 2000
The invention provides compounds of general formula (I), wherein: X is halogen or OSO.sub.2 R, where R represents H or is unsubstituted or hydroxy-or amino-substituted lower alkyl; Y is a nitro or amine group or a substituted derivative thereof; W is selected from the structures of f
5281620 Compounds having antitumor and antibacterial properties January 25, 1994
The novel class of xanthenone-4-acetic acids represented by the general formula (I) ##STR1## where R.sub.1 represents up to two of the groups lower alkyl, halogen, CF.sub.3, CN, NO.sub.2, NH.sub.2, CH.sub.2 COOH, OR.sub.2, OH, NHCOR.sub.2, NHSO.sub.2 R.sub.2, SR.sub.2, SO.sub.2 R
4904659 Substituted quinoline derivatives and pharmaceutical compositions thereof February 27, 1990
The novel class of substituted quinolines represented by the general formula (I): ##STR1## where each of R.sub.1 and R.sub.2 separately represents H or up to three of the groups lower alkyl, halogen, CF.sub.3, CN, SO.sub.2 CH.sub.3, NO.sub.2, OH, NH.sub.2, NHSO.sub.2 R.sub.3, NHC
4603125 Substituted o-phenylenediamine acridine compounds having antitumor activity July 29, 1986
Compounds represented by the general formula (I): ##STR1## in which R.sub.1 represents ##STR2## A and B each represent H or a lower alkane optionally substituted with amino and/or hydroxyl functions, except that A and B are not both H; R.sub.3 represents H, OCH.sub.3, CH.sub.
4590277 Acridinecarboxamide compounds May 20, 1986
4-Carboxamidoacridine compounds represented by the general formula (I), ##STR1## where R.sub.1 represents H, CH.sub.3 or NHR.sub.3, where R.sub.3 is H, COCH.sub.3, SO.sub.2 CH.sub.3, COPh, SO.sub.2 Ph or lower alkyl optionally substituted with hydroxyl and/or amino functions;R.sub.2
4537729 Dimethylphosphoramidates August 27, 1985
The novel class of compounds of the present invention represented by the general formula (I): ##STR1## in which R.sub.1 represents H or OCH.sub.3, R.sub.2 represents H, OCH.sub.3, CH.sub.3, halogen, NO.sub.2, NH.sub.2, NHCOCH.sub.3 or NHCOOCH.sub.3, andR.sub.3 and R.sub.4 individ
4479000 Certain acridinyl-phosphoramidate compounds October 23, 1984
The novel class of compounds of the present invention represented by the general formula (I): ##STR1## in which R.sub.1 represents H or OCH.sub.3,R.sub.2 represents H, OCH.sub.3, CH.sub.3, halogen, NO.sub.2, NH.sub.2, NHCOCH.sub.3 or NHCOOCH.sub.3, andR.sub.3 and R.sub.4 individually
4474961 1,10[8,9-Benz]phenanthroline October 2, 1984
Compounds represented by the general formula (I) ##STR1## in which R represents an aniline substituted in the para position by either --NHSO.sub.2 CH.sub.3 or --NHCOOCH.sub.3 and bearing either an --H or --OCH.sub.3 in the ortho position, or an aniline substituted in the para pos
4472582 3,5-Disubstituted-4'-(9-acridinylamino)-methane-sulfon-m-anisidide compounds having antitumor pr September 18, 1984
3,5-Disubstituted-4'-(9-acridinylamino)-methane-sulfon-m-anisidide compounds represented by the general formula ##STR1## in which R.sup.2 and R.sup.3 represent, respectively, --CH.sub.3 and --CONHCH.sub.3, --CH.sub.3 and --CONHCH.sub.2 CONH.sub.2, --Cl and --CONHCH.sub.2 CONH.sub
4366318 Compound having antitumor properties December 28, 1982
The compound 4'-(9-[4-[N-methyl-carboxamido]-5-methyl]acridinylamino)methanesulphon-m-a nisidide and acid addition salts thereof have antitumor properties.










 
 
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