| Patent Number |
Title Of Patent |
Date Issued |
| 6420363 |
Mono- or polyenic carboxylic acid derivatives |
July 16, 2002 |
| To provide novel compounds relating to retinoid which can substitute for retinoic acid used for preventing and treating several diseases and having antagonism against retinoid.Heterocyclic compounds represented by the general formula (1-I) or physiologically acceptable salts thereof:Comp |
| 6291508 |
Mono- or polyenic carboxylic acid derivatives |
September 18, 2001 |
| Mono- or polyenic carboxylic acid derived compounds of the formula (1-I) or a physiologically acceptable salt thereof:wherein R.sup.1 is hydrogen or a carboxyl-protecting group; R.sup.2 and R.sup.3 are each independently hydrogen, halogen, linear lower alkyl, branched lower alkyl linear |
| 6288064 |
Remedy for erection failure comprising fused pyridazine compound |
September 11, 2001 |
| The present invnetion provides a remedy for erectile dysfunction. The active ingredient thereof is a fused pyridazine compound represented by the following formula (I) or a pharmacologically acceptable salt thereof: ##STR1##(wherein the ring C represents a 5 or 6 membered ring optionally |
| 6133283 |
Mono- or polyenic carboxylic acid derivatives |
October 17, 2000 |
| To provide novel compounds relating to retinoid which can substitute for retinoic acid used for preventing and treating several diseases and having antagonism against retinoid. Heterocyclic compounds represented by the general formula (1-I) or physiologically acceptable salts thereof:Com |
| 6030964 |
Mono- or polyenic carboxylic acid derivatives |
February 29, 2000 |
| Compounds of the formula and compounds of the formula ##STR1## or their salts have the potent ability to bind to retinoic acid receptors thus useful in treating psoriasis and rheumatoid arthritis. |
| 5977125 |
Mono-or polyenic carboxylic acid derivatives |
November 2, 1999 |
| Compounds of the formula ##STR1## and compounds of the formula ##STR2## or their salts have the potent ability to bind to retinoic acid receptors thus useful in treating psoriasis and rheumatoid arthritis. |
| 5861418 |
Aminobenzoic acid derivatives |
January 19, 1999 |
| To provide a compound which exhibits a serotonin antagonism and an acetylcholine release accelerating activity at a well-balanced activity ratio. An aminobenzoic acid derivative represented by the general formula (I) or (II) or a pharmacologically acceptable salt thereof: ##STR1## |
| 5723472 |
Aminobenzoic acid derivatives |
March 3, 1998 |
| To provide a compound which exhibits a serotonin antagonism and an acetylcholine release accelerating activity at a well-balanced activity ratio. An aminobenzoic acid derivative represented by the general formula (I) or (II) or a pharmacologically acceptable salt thereof: ##STR1## |
| 5719303 |
Phosphonic acid derivatives |
February 17, 1998 |
| A phosphonic acid derivative which is useful for medically treating hyperlipemia, represented by the following general formula (I) or a pharmacologically acceptable salt thereof: ##STR1## Representative example of the compound according to the present invention is one represented |
| 5677311 |
Aminobenzoic acid derivatives |
October 14, 1997 |
| To provide a compound which exhibits a serotonin antagonism and an acetylcholine release accelerating activity at a well-balanced activity ratio. An aminobenzoic acid derivative represented by the general formula (I) or (II) or a pharmacologically acceptable salt thereof: ##STR1## |
| 5658925 |
Aminobenzoic acid derivatives |
August 19, 1997 |
| To provide a compound which exhibits a serotonin antagonism and an acetylcholine release accelerating activity at a well-balanced activity ratio. An aminobenzoic acid derivative represented by the general formula (I) or (II) or a pharmacologically acceptable salt thereof: ##STR1## |
| 5512579 |
Aminobenzoic acid derivatives |
April 30, 1996 |
| To provide a compound which exhibits a serotonin antagonism and an acetylcholine release accelerating activity at a well-balanced activity ratio. An aminobenzoic acid derivative represented by the general formula (I) or (II) or a pharmacologically acceptable salt thereof: ##STR1## |
| 5482937 |
1,4-diazepine derivative and its pharmaceutical use |
January 9, 1996 |
| A triazolo-1,4-di-azepine compound of the below given formula and a pharmacologically acceptable salt thereof are useful in the pharmaceutical field, especially in treating allergic diseases. ##STR1## in which R.sup.1 and R.sup.2 are hydrogen or an alkyl, R.sup.3 is hydrogen or a |
| 5476864 |
Glycerin derivative and its pharmacological use |
December 19, 1995 |
| A glycerin derivative having the following formula (I) or (I') and a pharmacologically acceptable salt thereof are useful to treat diseases caused by the platelet activating factor. ##STR1## |
| 5476863 |
Glycerin derivative and its pharmacological use |
December 19, 1995 |
| A glycerin derivative having the following formula (I) or (I') and a pharmacologically acceptable salt thereof are useful to treat diseases caused by the platelet activating factor. ##STR1## |
| 5468740 |
1,4-diazepine derivative and its pharmaceutical use |
November 21, 1995 |
| A triazolo-1,4-di-azepine compound of the below given formula and a pharmacologically acceptable salt thereof are disclosed and useful in the pharmaceutical field, especially to allergic diseases. ##STR1## in which R.sup.1 and R.sup.2 are hydrogen or an alkyl, R.sup.3 is hydrogen |
| 5453524 |
Phosphorus-containing isoprenoid derivatives |
September 26, 1995 |
| The present invention provides a phosphorus-containing isoprenoid derivative represented by the following general formula (I) or a pharmacologically acceptable salt thereof, which is useful as a preventive and therapeutic agent for diseases for which a squalene synthetase inhibiting |
| 5438045 |
1,4-diazepine derivative and its pharmaceutical use |
August 1, 1995 |
| A triazolo-1,4-di-azepine compound of the below given formula and a pharmacologically acceptable salt thereof are disclosed and useful in the pharmaceutical field, especially to allergic diseases. ##STR1## in which R1 and R2 are hydrogen or an alkyl, R3 is hydrogen or a halogen, |
| 5409909 |
1,4-diazepine derivative and its pharmaceutical use |
April 25, 1995 |
| A triazolo-1,4-di-azepine compound of the below given formula and a pharmacologically acceptable salt thereof are disclosed and useful in the pharmaceutical field, especially to treat allergic diseases: ##STR1## in which R1 and R2 are hydrogen or an alkyl, R3 is hydrogen or a halogen |
| 5385942 |
Quinone derivatives and pharmacological use |
January 31, 1995 |
| A quinone derivative useful in the treatment of hepatic diseases defined by the general formula: ##STR1## where X and Y may be the same or different from each other and are each a hydroxyl group, a group represented by the formula --(--OCH.sub.2 --).sub.n --OR.sup.6, wherein n is |
| 5382579 |
Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals |
January 17, 1995 |
| A triazolo-1,4-azepine compound of the below given formulas and a pharmacologically acceptable salt thereof are disclosed and useful in the pharmaceutical field, especially to allergic diseases. ##STR1## in which R1 and R2 are hydrogen or an alkyl, R3 is hydrogen or a halogen, R4 |
| 5319139 |
Naphthalene derivatives |
June 7, 1994 |
| Compounds of the formula: ##STR1## where R.sup.1 is a hydrogen atom or a lower alkyl group;R.sub.2 is a lower alkoxy group;R.sub.3 is a group ##STR2## Z is represented by the formula: ##STR3## where R.sub.2 and R.sub.3 may be the same or different from each other and eac |
| 5304553 |
1,4-diazepine derivative and its pharmaceutical use |
April 19, 1994 |
| A triazolo-1,4-di-azepine compound of the below given formula and a pharmacologically acceptable salt thereof are disclosed and useful in the pharmaceutical field, especially to allergic diseases, ##STR1## in which R.sup.1 and R.sup.2 are hydrogen or an alkyl, R.sup.3 is hydrogen |
| 5273985 |
Glycerin derivative and its pharmacological use |
December 28, 1993 |
| A glycerin derivative having the following formula (I) or (I') and a pharmacologically acceptable salt thereof are useful to treat diseases caused by the platelet activating factor. ##STR1## |
| 5262565 |
Naphthalene derivatives |
November 16, 1993 |
| Compounds of the formula: ##STR1## where R.sup.1 is a hydrogen atom or a lower alkyl group;R.sub.2 is a lower alkoxy group;R.sub.3 is a hydroxyl or lower alkoxy group;Z is represented by the formula: ##STR2## where R.sub.2 and R.sub.3 may be the same or different from each other |
| 5237091 |
Naphthalene derivatives |
August 17, 1993 |
| The present invention relates to a naphthalene derivative. More particularly, it relates to a naphthalene derivative exhibiting an excellent activity as a drug. |
| 5221671 |
Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals |
June 22, 1993 |
| A triazolo-1,4-di-azepine compound of the below given formulas and a pharmacologically acceptable salt thereof are disclosed and useful in the pharmaceutical field, especially to allergic diseases. ##STR1## in which R1 and R2 are hydrogen or an alkyl, R3 is hydrogen or a halogen, |
| 5210239 |
Ouinone derivatives and pharmacological use |
May 11, 1993 |
| A quinone derivative useful in the treatment of hepatic diseases defined by the general formula: ##STR1## where R1 is selected from the group consisting of alkyl, alkenly, alkynyl or heterocycle, R2 is a substituted nitrogen containing radical wherein the substituents on said nit |
| 5037827 |
Glycerin derivative and its pharmacological use |
August 6, 1991 |
| A glycerin derivative having the following formula (I) or (I') and a pharmacologically acceptable salt thereof are useful to treat diseases caused by the platelet activating factor. ##STR1## |
