Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Phenyl butyl nitrone compositions and methods for treatment of oxidative tissue damage










Image Number 2 for United States Patent #RE35112.

Compositions for treating tissue damage from ischemia contain PBN, or active derivatives thereof, which are active during ischemia in preventing ATP depletion of the cells which predisposes them to subsequent injury during reperfusion, and which are active during reperfusion as oxygen radical scavengers, in a suitable pharmaceutical carrier for systemic or local administration, especially to the CNS, spinal column and eyes. Based on animal studies, the dosage for treating damage due to stroke is in the range of 10 to 300 mg/kg. Similar dosages are useful in treating damage resulting from free radical generation during inflammation, either as a product of infection or exposure to inflammatory agents or abusive agents, including drugs and alcohol.








 
 
  Recently Added Patents
Use of deuterium oxide for the treatment of virus-based diseases of the respiratory tract
Method and apparatus for controlled reoxygenation
Semiconductor process
Display apparatus and control method thereof
Method for forming contact in an integrated circuit
Inhibitor of casein kinase 1delta and casein kinase 1E
Semiconductor device and method for fabricating the same
  Randomly Featured Patents
Isolating substrate noise by forming semi-insulating regions
Blade and cover assembly for a multiple function cutting tool
Spoke for reel
Manufacturing-process equipment
Radio navigation testing method and device using standard signal measuring and generating equipment
Machine element
Multi-faceted surgical needle
Using a multi-electrode probe in creating an electrophysiological profile during stereotactic neurosurgery
Sharing compiler optimizations in a multi-node system
Etch bleaching liquid with iron(III)ions