Resources Contact Us Home
Ribonucleotide reductase inhibitors and methods of use

Image Number 15 for United States Patent #8372983.

Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme, as well as methods of synthesizing these novel compounds. The compounds may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example certain cancer types, mitochondrial diseases, or degenerative diseases.

  Recently Added Patents
Highly specialized application protocol for email and SMS and message notification handling and display
Portable electronic device housing including hinge
State control of remote hosts for management of distributed applications
Device and method including a soldering process
Fiber optic cables and assemblies for fiber toward the subscriber applications
Image scanner and image forming apparatus
System and method to assess serviceability of device
  Randomly Featured Patents
Microwave applicator device
System and method for pattern recognition
Substituted benzamidine compounds which have useful pharmaceutical activity
Multi-sectioned arms for portable electronic devices
Method and system for facilitating electronic funds transactions
Fluorescent color lamp for LCD panel
Tools for 3D mesh and texture manipulation
Protein based food product
Compressed far-sighted eyeglasses within a case
Slidable room assembly