Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Ribonucleotide reductase inhibitors and methods of use










Image Number 12 for United States Patent #8372983.

Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme, as well as methods of synthesizing these novel compounds. The compounds may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example certain cancer types, mitochondrial diseases, or degenerative diseases.








 
 
  Recently Added Patents
Soybean EF1A promoter and its use in constitutive expression of transgenic genes in plants
Systems and methods for minimization or elimination of diffusion effects in a microfluidic system
Systems and methods for building axes, co-axes and paleo-geographic coordinates related to a stratified geological volume
Vehicle detection apparatus and method using magnetic sensor
Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
Method for modeling and analyzing linear time invariant systems with time delays
Measurement of an analyte on the skin using a hue angle
  Randomly Featured Patents
Capsule manufacture
Thick film conductor employing cobalt oxide
Apparatus for molding tires with a reinforcement below the tread surface
Applications of an algorithm that mimics cortical processing
Placemat and napkin ring assembly
Flexion and extension device
Integrated comparator circuit with four MOSFETS of defined transfer characteristics
Finger watch
Hot gas engine with tubular radial flow regenerators
Implementations of secure computation protocols