Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
On-chip polarimetry for high-throughput screening of nanoliter and smaller sample volumes










Image Number 5 for United States Patent #8134707.

A polarimetry technique for measuring optical activity that is particularly suited for high throughput screening employs a chip or substrate (22) having one or more microfluidic channels (26) formed therein. A polarized laser beam (14) is directed onto optically active samples that are disposed in the channels. The incident laser beam interacts with the optically active molecules in the sample, which slightly alter the polarization of the laser beam as it passes multiple times through the sample. Interference fringe patterns (28) are generated by the interaction of the laser beam with the sample and the channel walls. A photodetector (34) is positioned to receive the interference fringe patterns and generate an output signal that is input to a computer or other analyzer (38) for analyzing the signal and determining the rotation of plane polarized light by optically active material in the channel from polarization rotation calculations.








 
 
  Recently Added Patents
Forklift
Cytokine biomarkers as predictive biomarkers of clinical response for Glatiramer acetate
Case of electronic device having antenna pattern embedded therein and mold and method for manufacturing the same
Therapeutic rinse in a self-heating package
Far field telemetry operations between an external device and an implantable medical device during recharge of the implantable medical device via a proximity coupling
Method and apparatus for supporting delivery, sale and billing of perishable and time-sensitive goods such as newspapers, periodicals and direct marketing and promotional materials
Method and apparatus for band switching in wireless local access network
  Randomly Featured Patents
Antidepressant 1,1a,6,10b-tetrahydrodibenzo[a,e]-cyclopropa-[c]-cyclohepten-6-substitut ed oximes
Displaying layers of search results on a map
Coating material, method for production and use thereof for the production of adhesive tone and/or effect-generating coatings
Container and universal bracket system
Audio-visual carrel
C-frame sign
Fluid dispensing system
7-Morpholin-4yl-benzothiazole amide derivatives
Information recording apparatus, method and system, with increased likelihood for recording information at appropriate recording conditions
Method and apparatus for encoding and decoding binary data