Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
On-chip polarimetry for high-throughput screening of nanoliter and smaller sample volumes










Image Number 5 for United States Patent #8134707.

A polarimetry technique for measuring optical activity that is particularly suited for high throughput screening employs a chip or substrate (22) having one or more microfluidic channels (26) formed therein. A polarized laser beam (14) is directed onto optically active samples that are disposed in the channels. The incident laser beam interacts with the optically active molecules in the sample, which slightly alter the polarization of the laser beam as it passes multiple times through the sample. Interference fringe patterns (28) are generated by the interaction of the laser beam with the sample and the channel walls. A photodetector (34) is positioned to receive the interference fringe patterns and generate an output signal that is input to a computer or other analyzer (38) for analyzing the signal and determining the rotation of plane polarized light by optically active material in the channel from polarization rotation calculations.








 
 
  Recently Added Patents
Video recording and playing apparatus and its control method
Knife grip
Method and system for providing status of a machine
System and method for converting biomass to ethanol via syngas
Semiconductor power amplifier
Bootstrap gate driver
Battery-operated massager and soap dispensing wand
  Randomly Featured Patents
Hermetic terminal structure
Combination bipolar scissors and forceps instrument
Re-closable carton and blank therefor
Power throughput adjustment in flash memory
Umbrella with chamber and transport for a canopeum
Letter input apparatus and method
Two-motion switch for cordless lawnmower
Integrable, modular stackable multi-plant holder
Base station controlled handoff method and apparatus
Receivers including iterative map detection and related methods