Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
On-chip polarimetry for high-throughput screening of nanoliter and smaller sample volumes










Image Number 5 for United States Patent #8134707.

A polarimetry technique for measuring optical activity that is particularly suited for high throughput screening employs a chip or substrate (22) having one or more microfluidic channels (26) formed therein. A polarized laser beam (14) is directed onto optically active samples that are disposed in the channels. The incident laser beam interacts with the optically active molecules in the sample, which slightly alter the polarization of the laser beam as it passes multiple times through the sample. Interference fringe patterns (28) are generated by the interaction of the laser beam with the sample and the channel walls. A photodetector (34) is positioned to receive the interference fringe patterns and generate an output signal that is input to a computer or other analyzer (38) for analyzing the signal and determining the rotation of plane polarized light by optically active material in the channel from polarization rotation calculations.








 
 
  Recently Added Patents
Liquid-level sensor
PMI feedback with codebook interpolation
Shoe
Mass spectrometry device and method using ion-molecule reaction ionization
System for highlighting targets on head up displays with near focus plane
Electronic circuit having shared leakage current reduction circuits
Inductive antenna coupling
  Randomly Featured Patents
Method of attitude reacquisition for three-axis stabilized satellites using star recognition
Geometric panel lighting apparatus and methods
Methods of joint coding in mobile communication system
Antenna design utilizing a cavity architecture for global positioning system (GPS) applications
Method for generating contact holes with beveled sidewalls in intermediate oxide layers
Proportional micromechanical valve
Measuring system for determining the measurement uncertainty of measuring machines in the comparison of gearwheels with toothing standards
Isoquinoline derivatives
Method and device for electrostatic fixing of substrates with polarized molecules
Dynamic adjustment of mirror service policy for logical volumes in a disk drive system based on collected statistics