Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
On-chip polarimetry for high-throughput screening of nanoliter and smaller sample volumes










Image Number 5 for United States Patent #8134707.

A polarimetry technique for measuring optical activity that is particularly suited for high throughput screening employs a chip or substrate (22) having one or more microfluidic channels (26) formed therein. A polarized laser beam (14) is directed onto optically active samples that are disposed in the channels. The incident laser beam interacts with the optically active molecules in the sample, which slightly alter the polarization of the laser beam as it passes multiple times through the sample. Interference fringe patterns (28) are generated by the interaction of the laser beam with the sample and the channel walls. A photodetector (34) is positioned to receive the interference fringe patterns and generate an output signal that is input to a computer or other analyzer (38) for analyzing the signal and determining the rotation of plane polarized light by optically active material in the channel from polarization rotation calculations.








 
 
  Recently Added Patents
Integrated testing circuitry for high-frequency receiver integrated circuits
Image sensor and method for fabricating the same
Image forming apparatus
Image processing system and method
Television with a stand
Integrated disk driving module including a stepping motor integrally formed with a base unit
Fabric care compositions comprising front-end stability agents
  Randomly Featured Patents
Metal hydride heat pump system
Rotary connector
Trim saw with waste removal blades
Data I/O circuit with higher integration density for DRAM
Live combat simulation
Fluorinated 1,3-benzo- and 1,3-pyrido-dioxoles, their preparation and their use
Storage container
Ring
Bus driver circuit with low on-chip dissipation and/or pre-biasing of output terminal during live insertion
Unilaterally mat, sealable, UV-stabilized, flame resistant, co-extruded, biaxially oriented polyester film, method for the production and the use thereof