Resources Contact Us Home
Conjugates of biologically active proteins having a modified in vivo half-life

Image Number 2 for United States Patent #8129348.

Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating peptide motif, wherein the biologically active protein conjugate exhibits a modified plasma half-life compared to the intrinsic half-life of the unconjugated biologically active polypeptide or protein. Also disclosed are methods of making and using the conjugated proteins, as well as methods for determining whether a given conjugate exhibits a modified half life relative to the intrinsic half life of the unconjugated polypeptide.

  Recently Added Patents
Analysis device and an analysis apparatus using the analysis device
Systems and methods for analyzing telecommunications invoices for payment
Owner-brokered knowledge sharing machine
Resin composition and molded article
Nacelle cover
Process for making diethyl ether from acetic acid
Motor device and method of manufacturing the same
  Randomly Featured Patents
Method and apparatus for removing pre-placed prosthetic joints and preparing for their placement
Apparatus with semi-permeable membrane, and method for cultivating micro-organisms
Waterproof control knob assembly with integral switch
Shipment pouch
Encapsulated PC12 cell transplants for treatment of Parkinson's disease
Method and apparatus and program storage device for front tracking in hydraulic fracturing simulators
Human body: scanning, typing and profiling system
Enhanced leaching of minerals which form product layers
Switched capacitor scheme for offset compensated comparators
Process for preparing a salad product and an emulsion therefor