Resources Contact Us Home
Conjugates of biologically active proteins having a modified in vivo half-life

Image Number 2 for United States Patent #8129348.

Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating peptide motif, wherein the biologically active protein conjugate exhibits a modified plasma half-life compared to the intrinsic half-life of the unconjugated biologically active polypeptide or protein. Also disclosed are methods of making and using the conjugated proteins, as well as methods for determining whether a given conjugate exhibits a modified half life relative to the intrinsic half life of the unconjugated polypeptide.

  Recently Added Patents
System and method for enabling image recognition and searching of remote content on display
Methods and compositions for inhibiting progression to chronic cardiac failure
Vehicle control apparatus
High-efficiency preambles for communications systems over pseudo-stationary communication channels
Tap initialization of equalizer based on estimated channel impulse response
System and method for stranded file opens during disk compression utility requests
Nanogap device for field enhancement and a system for nanoparticle detection using the same
  Randomly Featured Patents
N-substituted 2-azetidinones
Dual-sided two-ply direct thermal image element
Olefin polymerization catalyst and process for preparing polypropylene and propylene block copolymers
Data transfer verification systems and methods
Chromogenic derivatives of bis-1,1-disubstituted ethylene and a process for preparing them
Apparatus and method for providing, retrieving, and using data guide information supplied in a digital vestigial sideband signal
Dispersions with nanoureas
Method for optimizing the accuracy of an electronic circuit
MAC reset and reconfiguration