Resources Contact Us Home
Conjugates of biologically active proteins having a modified in vivo half-life

Image Number 2 for United States Patent #8129348.

Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating peptide motif, wherein the biologically active protein conjugate exhibits a modified plasma half-life compared to the intrinsic half-life of the unconjugated biologically active polypeptide or protein. Also disclosed are methods of making and using the conjugated proteins, as well as methods for determining whether a given conjugate exhibits a modified half life relative to the intrinsic half life of the unconjugated polypeptide.

  Recently Added Patents
Image processing apparatus, image display apparatus, and image processing method
Quantitative sleep analysis system and method
Carrier sense multiple access (CSMA) protocols for power line communications (PLC)
Print control server, print controlling method, and print control program
Method for radiation sterilization of medical devices
Non-volatile memory cell containing a nano-rail electrode
  Randomly Featured Patents
Windshield washing service unit
Carbon-coated Li-containing powders and process for production thereof
Child's bounce toy with safety net
Carrier positioning for wide-array inkjet printhead assembly
Anti-vibration linear motion guide unit
Zigzag cooled turbine airfoil
Dehydrogenation catalyst
Spreader unit for multi-legged stands
Penicillin antibiotics