Resources Contact Us Home
Conjugates of biologically active proteins having a modified in vivo half-life

Image Number 2 for United States Patent #8129348.

Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating peptide motif, wherein the biologically active protein conjugate exhibits a modified plasma half-life compared to the intrinsic half-life of the unconjugated biologically active polypeptide or protein. Also disclosed are methods of making and using the conjugated proteins, as well as methods for determining whether a given conjugate exhibits a modified half life relative to the intrinsic half life of the unconjugated polypeptide.

  Recently Added Patents
Method of isolating human neuroepithelial precursor cells from human fetal tissue
Method for using a super-slippery thin layer characterized by the method for making same
Under bump passive components in wafer level packaging
Power collecting device, power measuring device, and power collecting method
Method for the synthesis of an array of metal nanowire capable of supporting localized plasmon resonances and photonic device comprising said array
Method, system and computer program product for verifying floating point divide operation results
Configuration method and system of complex network and configuration and management module of server resources
  Randomly Featured Patents
System and method for providing short message service in wireless communication system
Method and apparatus for reconfiguring striped logical devices in a disk array storage
Vacuum control device for holding a workpiece
Brushless DC motor
Resistance random access memory structure for enhanced retention
Connection configuration for rigid substrates
Combination extendible divot tool and golf ball retriever
Device for aligning two shell molds
Retention-time control and error management in a cache system comprising dynamic storage