Resources Contact Us Home
Conjugates of biologically active proteins having a modified in vivo half-life

Image Number 2 for United States Patent #8129348.

Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating peptide motif, wherein the biologically active protein conjugate exhibits a modified plasma half-life compared to the intrinsic half-life of the unconjugated biologically active polypeptide or protein. Also disclosed are methods of making and using the conjugated proteins, as well as methods for determining whether a given conjugate exhibits a modified half life relative to the intrinsic half life of the unconjugated polypeptide.

  Recently Added Patents
Document layout method
Methods for testing OData services
SONOS stack with split nitride memory layer
Systems and methods of device-free motion detection and presence detection
Secure data exchange between data processing systems
Power-saving receiver
Antenna device and wireless communication apparatus
  Randomly Featured Patents
Sealable dome assembly
Ubiquitin-lytic peptide fusion gene constructs, protein products deriving therefrom, and methods of making and using same
Multiple-purpose machine tool
Compositions and methods for enhancing immunogenicity of antigens
Methods of manufacturing non-volatile memory devices having insulating layers treated using neutral beam irradiation
Vibration damping pivot bushing
Polishing tool component
Biological specimen carrier system
Intake nozzle for a pump
Methods and apparatus for ultrasound imaging using combined scan patterns