Resources Contact Us Home
Conjugates of biologically active proteins having a modified in vivo half-life

Image Number 2 for United States Patent #8129348.

Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating peptide motif, wherein the biologically active protein conjugate exhibits a modified plasma half-life compared to the intrinsic half-life of the unconjugated biologically active polypeptide or protein. Also disclosed are methods of making and using the conjugated proteins, as well as methods for determining whether a given conjugate exhibits a modified half life relative to the intrinsic half life of the unconjugated polypeptide.

  Recently Added Patents
Management of memory array with magnetic random access memory (MRAM)
Wafer-level chip scale package
Method for producing SOI substrate and SOI substrate
Antisense modulation of C-reactive protein expression
System and method for computational unification of heterogeneous implicit and explicit processing elements
Mode detection for DVB receiver
Key management policies for cryptographic keys
  Randomly Featured Patents
Packaging material for forming an easy-opening reclosable packaging material and package
Steerable catheter and self-mounting center support for use with same
Flexible hydraulic structure and system for replacing a damaged portion thereof
QoS scheduling methods for WLANs with heterogenous applications
Current supply arrangement for household appliances and method of making the same
Video encoding and decoding
Electronic bowling scoring system with video communication interface between manager console and lane score consoles
Lithography for pitch reduction
Enablement of social networking based on asset ownership
Noise reduction in a stereo receiver