Resources Contact Us Home
Conjugates of biologically active proteins having a modified in vivo half-life

Image Number 2 for United States Patent #8129348.

Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating peptide motif, wherein the biologically active protein conjugate exhibits a modified plasma half-life compared to the intrinsic half-life of the unconjugated biologically active polypeptide or protein. Also disclosed are methods of making and using the conjugated proteins, as well as methods for determining whether a given conjugate exhibits a modified half life relative to the intrinsic half life of the unconjugated polypeptide.

  Recently Added Patents
Fiber optic cables and assemblies for fiber toward the subscriber applications
Display screen with graphical user interface
Projection-type video-image display apparatus
Support for a parameterized query/view in complex event processing
High power insulated gate bipolar transistors
System and method for burst separation and extended interleaving length
Case for electronic device
  Randomly Featured Patents
Method and apparatus for drying wafers
Method and apparatus for analyzing network infrastructure
Gas appliance with flash suppressor
Method of isolating and culturing mesenchymal stem cell derived from umbilical cord blood
Strain sensor employing piezoelectric material
Blow molded venous drip chamber for hemodialysis
ATM redundancy leveraging virtualization technology
Sprinkler assembly for attachment to a piping system
Method and apparatus for simplifying field prediction motion estimation