Resources Contact Us Home
Cholesterol loaded insect cell membranes as test proteins

Image Number 18 for United States Patent #8129197.

The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane.

  Recently Added Patents
Liquid crystal display wherein the data lines covered by each pixel electrode are supplied with data signals of opposite polarities
Memory device and method for repairing a semiconductor memory
Electron beam manipulation system and method in X-ray sources
Conductor-mixed active electrode material, electrode structure, rechargeable battery, and manufacturing method of conductor-mixed active electrode material
System and method of interfacing co-processors and input/output devices via a main memory system
Light emitting device and light emitting device package
Flood protection apparatus and container data center including the same
  Randomly Featured Patents
Signal generator
Method and apparatus for sequentially collecting and analyzing real time data with interactive monitoring
Aerobic exercise floor system
Switching valve with slider
Temporal release of growth factors from 3D micro rod scaffolds for tissue regeneration
Device for converting linear reciprocating motion to rotary motion
Printed board with a pin for mounting a component
Landing approach aid for aircraft
Dual CPU on-chip-debug low-gate-count architecture with real-time-data tracing