Resources Contact Us Home
Cholesterol loaded insect cell membranes as test proteins

Image Number 18 for United States Patent #8129197.

The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane.

  Recently Added Patents
Micromechanical component, device for beam deflection of monochromatic light, and spectrometer
Semiconductor device
Device and method for superimposing patterns on images in real time, particularly for guidance by location
Automatic portable electronic device configuration
Method for eliciting an immune response to human telomerase reverse transcriptase
Fluid conduit with PTC fabric heating
Concentrating photovoltaic system module with actuator control
  Randomly Featured Patents
Separation process
Dynamic stereophonic enchancement signal processing system
Resonant tunneling device with two-dimensional quantum well emitter and base layers
Analyte monitoring device and methods of use
Bra hanger
Magnetic disc recording system employing two stage actuators for simultaneous accesses through multiple recording heads
Colored zinc coating
Method and apparatus for creating a graduated distribution of granule materials in a fiber mat
Medical sponge tray
Elastomer composition