Resources Contact Us Home
Cholesterol loaded insect cell membranes as test proteins

Image Number 18 for United States Patent #8129197.

The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane.

  Recently Added Patents
Systems, methods, and media for firewall control via remote system information
Protecting a gaming machine from rogue code
Determination of copy number variations using binomial probability calculations
Multi-carrier operation for wireless systems
Puncture resistant fabric
Device and method including a soldering process
Package for product
  Randomly Featured Patents
Cannula assembly with squeeze operated valve
Monitoring apparatus for direct wire alarm system
Acrylate-filled flexible tube, which opens on contact with water
Method for repair and reconstruction of ruptured ligaments or tendons and for treatment of ligament and tendon injuries
Method of managing power consumption of a network interface
High isolation multiple carrier system architecture for communications
Methods for identifying ligand binding sites in a biomolecule
Alphanumeric display means for computer-linked typewriter consoles
Memory mapping method in a data processing system
Coated semiconductor devices for neutron detection