Resources Contact Us Home
Cholesterol loaded insect cell membranes as test proteins

Image Number 18 for United States Patent #8129197.

The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane.

  Recently Added Patents
Air filter
System and method for distributed security
Radio transmitter and radio receiver with channel condition assessment
Node and wireless sensor network comprising the node
Method for driving bistable display device
Escalating data backup protection in response to a failure in a cluster of nodes
System for highlighting targets on head up displays with near focus plane
  Randomly Featured Patents
Memory array utilizing low voltage Fowler-Nordheim Flash EEPROM cell
Device for ultrasonic peening of metals
Flap folding mechanism for manufacture of boxes with integrally reinforced walls
Pivotally mounted grass catcher for riding mower
CMOS transconductor circuit with high linearity
Apparatus and process for quick freezing of blood plasma
Device for reducing dead space in a ventilator system
Video reproduction device
Light modulator using large area light sources
Filter for continuous filtering of a suspension under pressure