Resources Contact Us Home
Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses

Image Number 17 for United States Patent #8129185.

Based upon a strong correlation between regulator T cells (Treg cells) and suppressing or preventing a cytotoxic T cell response, provided are methods for the production of ex vivo activated and culture-expanded isolated CD4.sup.+CD25.sup.+ suppressor Treg cells for the prevention or suppression of immune reactions in a host, particularly in a human host, and including autoimmune responses. The resulting ex vivo culture-expanded Treg cells provide a sufficient amount of otherwise low numbers of such cells, having long term suppressor capability to permit therapeutic uses, including the preventing, suppressing, blocking or inhibiting the rejection of transplanted tissue in a human or other animal host, or protecting against graft vs host disease. Also provided are therapeutic and immunosuppressive methods utilizing the ex vivo culture-expanded Treg cells for human treatment, and high efficiency methods for research use.

  Recently Added Patents
Negative active material for a rechargeable lithium battery, a method of preparing the same, and a rechargeable lithium battery comprising the same
Managing job execution
Lithographic apparatus and device manufacturing method
Systems, methods, and apparatus to prepare a mobile device for provisioning
Imaging device
Toilet bowl
Human and mouse targeting peptides identified by phage display
  Randomly Featured Patents
Eating utensil
Method for the preparation of flexible polyester polyurethane foams
Inside boat thruhole fitting clearing
Electroless copper plating solution
.alpha..sub.2 -Adrenoceptor antagonistic benzoquinolizines
Process for production of a recombinant protein and a fusion protein
Cutter for square timber hewing machine
1,6-naphthyridinone derivatives having angiotension II antagonist activity
Prosthetic intervertebral discs
Method of sharing and transferring information between ISDN telephones