Resources Contact Us Home
Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses

Image Number 17 for United States Patent #8129185.

Based upon a strong correlation between regulator T cells (Treg cells) and suppressing or preventing a cytotoxic T cell response, provided are methods for the production of ex vivo activated and culture-expanded isolated CD4.sup.+CD25.sup.+ suppressor Treg cells for the prevention or suppression of immune reactions in a host, particularly in a human host, and including autoimmune responses. The resulting ex vivo culture-expanded Treg cells provide a sufficient amount of otherwise low numbers of such cells, having long term suppressor capability to permit therapeutic uses, including the preventing, suppressing, blocking or inhibiting the rejection of transplanted tissue in a human or other animal host, or protecting against graft vs host disease. Also provided are therapeutic and immunosuppressive methods utilizing the ex vivo culture-expanded Treg cells for human treatment, and high efficiency methods for research use.

  Recently Added Patents
Subscribing to content
Focus detection device and imaging apparatus having the same
Over the counter medicinal container with surface ornamentation
Network decoys
Mounting apparatus for PCI card
Developing device
Method and apparatus for error correction in MBMS receipt system
  Randomly Featured Patents
Measuring corrosion rate under specified heat transfer conditions
System and method for protecting eye safety during operation of a fiber optic transceiver
Money counting machine
Oral hygiene method
Laundry treatment apparatus
Mono-, oligo- and poly-3-(1,1-difluoroalkyl)thiophenes and their use as charge transport materials
Superconductor and noble metal composite films
Hardware protection system for sensitive electronic-data modules protecting against external manipulations
Process for making soil release polymer granules
Insecticidal phenylureas and methods of use thereof