Resources Contact Us Home
Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses

Image Number 17 for United States Patent #8129185.

Based upon a strong correlation between regulator T cells (Treg cells) and suppressing or preventing a cytotoxic T cell response, provided are methods for the production of ex vivo activated and culture-expanded isolated CD4.sup.+CD25.sup.+ suppressor Treg cells for the prevention or suppression of immune reactions in a host, particularly in a human host, and including autoimmune responses. The resulting ex vivo culture-expanded Treg cells provide a sufficient amount of otherwise low numbers of such cells, having long term suppressor capability to permit therapeutic uses, including the preventing, suppressing, blocking or inhibiting the rejection of transplanted tissue in a human or other animal host, or protecting against graft vs host disease. Also provided are therapeutic and immunosuppressive methods utilizing the ex vivo culture-expanded Treg cells for human treatment, and high efficiency methods for research use.

  Recently Added Patents
Universal tablet and smartphone holder
Electronic package with fluid flow barriers
Touch panel structure and manufacturing method thereof
Quick mounting device
Method and system for coordinating client and host security modules
Bipolar transistor with diffused layer between deep trench sidewall and collector diffused layer
Accessory sleeve
  Randomly Featured Patents
Apparatus for and a method of performing anastomosis of blood vessels
Cable-and-pulley devices having intermediate tension isolators for exercise machines
Middle distillate fuel additive
Continuously variable transmission
Automatic bending machine for manufacturing of steel rule cutting dies
Extended call handling functionality using multi-network simulcasting
Work vehicle
Smart microwave packaging structures
Modulator with biasing circuit to minimize output distortion
Razors providing pivoting and swivelling razor head support