Resources Contact Us Home
Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses

Image Number 17 for United States Patent #8129185.

Based upon a strong correlation between regulator T cells (Treg cells) and suppressing or preventing a cytotoxic T cell response, provided are methods for the production of ex vivo activated and culture-expanded isolated CD4.sup.+CD25.sup.+ suppressor Treg cells for the prevention or suppression of immune reactions in a host, particularly in a human host, and including autoimmune responses. The resulting ex vivo culture-expanded Treg cells provide a sufficient amount of otherwise low numbers of such cells, having long term suppressor capability to permit therapeutic uses, including the preventing, suppressing, blocking or inhibiting the rejection of transplanted tissue in a human or other animal host, or protecting against graft vs host disease. Also provided are therapeutic and immunosuppressive methods utilizing the ex vivo culture-expanded Treg cells for human treatment, and high efficiency methods for research use.

  Recently Added Patents
Systems and methods for remotely troubleshooting a software problem occurring on a computing device
Electrical connector
Cigar cutter
Method for determining a steam dryness factor
Short-acting benzodiazepine salts and their polymorphic forms
Customer initiated mobile diagnostics service
Foot pad
  Randomly Featured Patents
Pet food tray
Light-emitting device
Carrying pouch attachable to garments
Light emitter substrate and image displaying apparatus using the same
Method and apparatus for updating and invalidating store data
Semiconductor memory device, memory system and electronic instrument
Cooling system for gasifier burner operating in a high pressure environment
Cyclic amide compounds
Preparation of electrodes and Ni/MHx electrochemical storage cell