Resources Contact Us Home
Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses

Image Number 17 for United States Patent #8129185.

Based upon a strong correlation between regulator T cells (Treg cells) and suppressing or preventing a cytotoxic T cell response, provided are methods for the production of ex vivo activated and culture-expanded isolated CD4.sup.+CD25.sup.+ suppressor Treg cells for the prevention or suppression of immune reactions in a host, particularly in a human host, and including autoimmune responses. The resulting ex vivo culture-expanded Treg cells provide a sufficient amount of otherwise low numbers of such cells, having long term suppressor capability to permit therapeutic uses, including the preventing, suppressing, blocking or inhibiting the rejection of transplanted tissue in a human or other animal host, or protecting against graft vs host disease. Also provided are therapeutic and immunosuppressive methods utilizing the ex vivo culture-expanded Treg cells for human treatment, and high efficiency methods for research use.

  Recently Added Patents
Multi-screen synthesizing display apparatus and method
Controller-integrated electric rotating machine with a shifted control circuit
Handover of a communication device
Connection processing method in wireless communication system, wireless base station, and wireless terminal
Control channel signaling and acquisition for carrier aggregation
A/D converter
Method and apparatus to reduce a quantity of error detection/correction bits in memory coupled to a data-protected processor port
  Randomly Featured Patents
Smoking device
Method and apparatus for managing peripheral devices in a medical imaging system
Urea-compounds active as vanilloid receptor antagonists for the treatment of pain
Method of fabricating a projection for resistance welding
Multi-layer circuit board having at least two or more circuit patterns connected
Treatment of presbyopia and other eye disorders
Hydronaphtho[2,3-c]furan derivatives and process for the preparation thereof
Stylus attachment structure for IT products
Sinterable aluminum nitride composition, sintered body from this composition and process for producing the sintered body
Method for identifying hearing aids within the scope of wireless programming