Resources Contact Us Home
Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses

Image Number 17 for United States Patent #8129185.

Based upon a strong correlation between regulator T cells (Treg cells) and suppressing or preventing a cytotoxic T cell response, provided are methods for the production of ex vivo activated and culture-expanded isolated CD4.sup.+CD25.sup.+ suppressor Treg cells for the prevention or suppression of immune reactions in a host, particularly in a human host, and including autoimmune responses. The resulting ex vivo culture-expanded Treg cells provide a sufficient amount of otherwise low numbers of such cells, having long term suppressor capability to permit therapeutic uses, including the preventing, suppressing, blocking or inhibiting the rejection of transplanted tissue in a human or other animal host, or protecting against graft vs host disease. Also provided are therapeutic and immunosuppressive methods utilizing the ex vivo culture-expanded Treg cells for human treatment, and high efficiency methods for research use.

  Recently Added Patents
Nonvolatile semiconductor storage device and a manufacturing method thereof
Regulating a supply voltage provided to a load circuit
Dynamic data filtering system and method
Statistical information collection from one or more device(s) in storage communication with a computing platform
Animation control apparatus, animation control method, and non-transitory computer readable recording medium
Power supply architecture system designer
Prevention and treatment of oxidative stress disorders by gluthathione and phase II detoxification enzymes
  Randomly Featured Patents
Aqueous shower rinsing composition and a method for keeping showers clean
Necropsy board for small animals
High-efficiency fuel cell power system with power generating expander
Table for operating room
Method of peroxide bleaching of pulp pretreated with a sequestering agent then with a sulphite and reducing agent
Machine frame with cross members and side members for slicers
Variable slot bypass injector system
Processing occluded windows during application sharing
Copying method and copier for film
Device for controlling the temperature of rooms in a building