Resources Contact Us Home
Antibodies specific for soluble amyloid beta peptide protofibrils and uses thereof

Image Number 14 for United States Patent #8106164.

The invention pertains to the development of antibodies that specifically bind amyloid beta protein (Abeta) in its protofibril conformation. The invention also comprises methods of using anti-Abeta protofibril antibodies to diagnose or treat Alzheimer's disease, Down's syndrome Lewybody dementia, vascular dementia, and other neurodegenerative disorders. Furthermore, the invention pertains to the use of anti-Abeta protofibril antibodies to screen and identify substances that will modulate protofibril activity or formation in vitro or in vivo. The invention also pertains to methods for synthesising pure Abeta protofibril antigens as well as to a method for stabilising Abeta protofibrils antigens as well as to a method for stabilising Abeta protofibrils.

  Recently Added Patents
System and method for receiving MBMS broadcasting service
Lentiviral gene transfer vectors and their medicinal applications
Device, system, and method for logging near field communications tag interactions
Method of inspecting wafer
Automated incorporation of expert feedback into a monitoring system
Dynamic trunk distribution on egress
Digital processing method and system for determination of optical flow
  Randomly Featured Patents
Image processing method and apparatus for color enhancement and correction
Method of increasing end point detection capability of reactive ion etching by adding pad area
System and method for sales tax automatic declaration
Building intercom system
Flexible JTAG architecture
System and method for visual search in a video media player
Extrudable, low-migration organic silicone copolymers of high transparency, their preparation and use
Electrophotocopying machine of electrostatic latent image transfer type
Method of forming a composite structural member