Resources Contact Us Home
Antibodies specific for soluble amyloid beta peptide protofibrils and uses thereof

Image Number 14 for United States Patent #8106164.

The invention pertains to the development of antibodies that specifically bind amyloid beta protein (Abeta) in its protofibril conformation. The invention also comprises methods of using anti-Abeta protofibril antibodies to diagnose or treat Alzheimer's disease, Down's syndrome Lewybody dementia, vascular dementia, and other neurodegenerative disorders. Furthermore, the invention pertains to the use of anti-Abeta protofibril antibodies to screen and identify substances that will modulate protofibril activity or formation in vitro or in vivo. The invention also pertains to methods for synthesising pure Abeta protofibril antigens as well as to a method for stabilising Abeta protofibrils antigens as well as to a method for stabilising Abeta protofibrils.

  Recently Added Patents
Terminal box assembly
Strongly bound carbon nanotube arrays directly grown on substrates and methods for production thereof
Device and method for controlling brightness of organic light emitting diode display
System, apparatus, and method for fast startup of USB devices
Subcarrier cluster-based power control in wireless communications
Method of analyzing cell structures and their components
Manufacturing process for cellular screening substratum, resultant substratum, and method and apparatus for screening
  Randomly Featured Patents
Process and apparatus for oxidizing organic compounds
Thermal anemometer aircraft airspeed gust component transducer
Tracking system incorporating business intelligence
Sigma tuning of gaussian kernels: detection of ischemia from magnetocardiograms
Syringe assembly
Dynamically programmable receiver
Protein kinase c. modulators. d.
Cannula interface
A cDNA clone for human tyrosinase
Process for the preparation of p-haloalkoxyanilines