Resources Contact Us Home
Antibodies specific for soluble amyloid beta peptide protofibrils and uses thereof

Image Number 14 for United States Patent #8106164.

The invention pertains to the development of antibodies that specifically bind amyloid beta protein (Abeta) in its protofibril conformation. The invention also comprises methods of using anti-Abeta protofibril antibodies to diagnose or treat Alzheimer's disease, Down's syndrome Lewybody dementia, vascular dementia, and other neurodegenerative disorders. Furthermore, the invention pertains to the use of anti-Abeta protofibril antibodies to screen and identify substances that will modulate protofibril activity or formation in vitro or in vivo. The invention also pertains to methods for synthesising pure Abeta protofibril antigens as well as to a method for stabilising Abeta protofibrils antigens as well as to a method for stabilising Abeta protofibrils.

  Recently Added Patents
Dual protocol input device
Liquid crystal display device
Para-xylylene based microfilm elution devices
Semiconductor device and fabrication method
Lubricating oil compositions
MOS resistor apparatus and methods
Systems and methods for selective text to speech synthesis
  Randomly Featured Patents
Method for navigation within a set of audio documents by means of a graphic interface and receiver for navigation by said method
Fundamental frequency variation for a musical tone generator using stored waveforms
Method for recovery of carbon and combinations of hydrocarbons from polymers, preferably in the form of disposed tires, by pyrolysis in a pyrolysis reactor
Method and apparatus for random and sequential accessing in dynamic memories
Halogenated polyurethanes
Blade opening scabbard for folding knife
Vertical semiconductor device and method of manufacturing the same
Device for electrochemical detection or measurement
Liquid multipurpose-cleaning compositions with effective foam control