Resources Contact Us Home
Antibodies specific for soluble amyloid beta peptide protofibrils and uses thereof

Image Number 14 for United States Patent #8106164.

The invention pertains to the development of antibodies that specifically bind amyloid beta protein (Abeta) in its protofibril conformation. The invention also comprises methods of using anti-Abeta protofibril antibodies to diagnose or treat Alzheimer's disease, Down's syndrome Lewybody dementia, vascular dementia, and other neurodegenerative disorders. Furthermore, the invention pertains to the use of anti-Abeta protofibril antibodies to screen and identify substances that will modulate protofibril activity or formation in vitro or in vivo. The invention also pertains to methods for synthesising pure Abeta protofibril antigens as well as to a method for stabilising Abeta protofibrils antigens as well as to a method for stabilising Abeta protofibrils.

  Recently Added Patents
Plants and seeds of hybrid corn variety CH424126
Method for producing a sulfonated polyarylether block copolymer
Random access point (RAP) formation using intra refreshing technique in video coding
Liquid-level sensor
Method of manufacturing toner
Low offset, fast response voltage controlled current source and controlling method thereof
White polyester film and surface light source therewith
  Randomly Featured Patents
Electronic certificate signature program
Bearing assembly
Cigar storage and transportation container
Charm or the like
Lithographic apparatus, contaminant trap, and device manufacturing method
Scanning apparatus
Scalable stack-type DRAM memory structure and its manufacturing methods
Semiconductor memory device
Biaromatic compounds and pharmaceutical and cosmetic compositions comprising them
Double effect distribution sequential valve shaft assembly