Resources Contact Us Home
Antibodies specific for soluble amyloid beta peptide protofibrils and uses thereof

Image Number 14 for United States Patent #8106164.

The invention pertains to the development of antibodies that specifically bind amyloid beta protein (Abeta) in its protofibril conformation. The invention also comprises methods of using anti-Abeta protofibril antibodies to diagnose or treat Alzheimer's disease, Down's syndrome Lewybody dementia, vascular dementia, and other neurodegenerative disorders. Furthermore, the invention pertains to the use of anti-Abeta protofibril antibodies to screen and identify substances that will modulate protofibril activity or formation in vitro or in vivo. The invention also pertains to methods for synthesising pure Abeta protofibril antigens as well as to a method for stabilising Abeta protofibrils antigens as well as to a method for stabilising Abeta protofibrils.

  Recently Added Patents
Managing job execution
Semiconductor apparatus
Synchronization of web applications and media
Methods of diagnosing a plasmodium infection
Electrical installation arrangement
Consistent retention and disposition of managed content and associated metadata
Use of natriuretic peptide for treating heart failure
  Randomly Featured Patents
Microporous thermal insulation molding
Liquid crystal display and method of manufacturing a liquid crystal display with a barrier formed of TFT materials
Free item distribution among multiple free lists during garbage collection for more efficient object allocation
Production of amines from alcohols
Methods for modulating strobili development in gymnosperm trees
Rechargeable battery and sealing plug for a rechargeable battery
Personal wireless communication device wireless connectivity arrangement
Entertainment base cabinet
Water activated release triggering mechanism
Gear teeth