Resources Contact Us Home
Antibodies specific for soluble amyloid beta peptide protofibrils and uses thereof

Image Number 14 for United States Patent #8106164.

The invention pertains to the development of antibodies that specifically bind amyloid beta protein (Abeta) in its protofibril conformation. The invention also comprises methods of using anti-Abeta protofibril antibodies to diagnose or treat Alzheimer's disease, Down's syndrome Lewybody dementia, vascular dementia, and other neurodegenerative disorders. Furthermore, the invention pertains to the use of anti-Abeta protofibril antibodies to screen and identify substances that will modulate protofibril activity or formation in vitro or in vivo. The invention also pertains to methods for synthesising pure Abeta protofibril antigens as well as to a method for stabilising Abeta protofibrils antigens as well as to a method for stabilising Abeta protofibrils.

  Recently Added Patents
Account managing device, image processing system, and storage medium
Server-side web analytics system and method
MRAM with sidewall protection and method of fabrication
Image processing apparatus and method configured to calculate defocus amount of designated area
Semiconductor device and manufacturing method
Bessel beam plane illumination microscope
Adjusting dental prostheses based on soft tissue
  Randomly Featured Patents
Chemotactic agents for t-cells
Tray apparatus for vehicles
Utilization of a cycloaliphatic carbinol as perfuming ingredient
Electrical connector
Device for receiving, from a fixed electric connection, adapting to length, and holding conductors for the electric current supply of movable consumers
Measurement while drilling bi-directional pulser operating in a near laminar annular flow channel
Process cartridge having drive mount for photosensitive drum
Systems and methods for fast terminal synchronization in a wireless communication system
Focus detecting device with photo-sensor array