Resources Contact Us Home
Antibodies specific for soluble amyloid beta peptide protofibrils and uses thereof

Image Number 14 for United States Patent #8106164.

The invention pertains to the development of antibodies that specifically bind amyloid beta protein (Abeta) in its protofibril conformation. The invention also comprises methods of using anti-Abeta protofibril antibodies to diagnose or treat Alzheimer's disease, Down's syndrome Lewybody dementia, vascular dementia, and other neurodegenerative disorders. Furthermore, the invention pertains to the use of anti-Abeta protofibril antibodies to screen and identify substances that will modulate protofibril activity or formation in vitro or in vivo. The invention also pertains to methods for synthesising pure Abeta protofibril antigens as well as to a method for stabilising Abeta protofibrils antigens as well as to a method for stabilising Abeta protofibrils.

  Recently Added Patents
Flat panel crystal display employing simultaneous charging of main and subsidiary pixel electrodes
System for determining potential lot consolidation during manufacturing
Boring machine
Magnetic disk and manufacturing method thereof
Implant for performance enhancement of selected transistors in an integrated circuit
Generating a funding and investment strategy associated with an underfunded pension plan
Method and apparatus for accessing and downloading information from the internet
  Randomly Featured Patents
Container for surgical patties
Input circuits including boosted voltage and related methods
Printing unit for blanket-to-blanket printing
Pre-curved cochlear implant electrode array
Compressed foam article
Method of detecting cam overload in a plastic molding apparatus
Cascading-synchronous mixer and method of operation
Dimethyl-benzoic acid compounds
Optimum placement method of circuit blocks in semiconductor integrated circuit