Resources Contact Us Home
Antibodies specific for soluble amyloid beta peptide protofibrils and uses thereof

Image Number 14 for United States Patent #8106164.

The invention pertains to the development of antibodies that specifically bind amyloid beta protein (Abeta) in its protofibril conformation. The invention also comprises methods of using anti-Abeta protofibril antibodies to diagnose or treat Alzheimer's disease, Down's syndrome Lewybody dementia, vascular dementia, and other neurodegenerative disorders. Furthermore, the invention pertains to the use of anti-Abeta protofibril antibodies to screen and identify substances that will modulate protofibril activity or formation in vitro or in vivo. The invention also pertains to methods for synthesising pure Abeta protofibril antigens as well as to a method for stabilising Abeta protofibrils antigens as well as to a method for stabilising Abeta protofibrils.

  Recently Added Patents
Identification of biomarkers in biological samples and methods of using same
Detection system and method for mobile device application
Using sets of OTDR receive fibers with different lengths of marker events to verify optical fiber connectivity
Liquid crystal display device
Apparatus for electrographic printing or copying
Data driver and liquid crystal display device using the same
Mobile phone
  Randomly Featured Patents
System and method for individualized training of hearing aid users
Method and apparatus for automatically cutting and shuffling playing cards
Electric motor
Electric cylinder for actuating a door lock and a cylinder door lock
Module having a latch
Plasma processor
Pulsed electron beam source and its use
Decryption method and device, and access right authentication method and apparatus
Pharmaceutical composition useful for nucleic acid transfection, and use thereof
Buried biasing wells in FETS