Resources Contact Us Home
Antibodies specific for soluble amyloid beta peptide protofibrils and uses thereof

Image Number 14 for United States Patent #8106164.

The invention pertains to the development of antibodies that specifically bind amyloid beta protein (Abeta) in its protofibril conformation. The invention also comprises methods of using anti-Abeta protofibril antibodies to diagnose or treat Alzheimer's disease, Down's syndrome Lewybody dementia, vascular dementia, and other neurodegenerative disorders. Furthermore, the invention pertains to the use of anti-Abeta protofibril antibodies to screen and identify substances that will modulate protofibril activity or formation in vitro or in vivo. The invention also pertains to methods for synthesising pure Abeta protofibril antigens as well as to a method for stabilising Abeta protofibrils antigens as well as to a method for stabilising Abeta protofibrils.

  Recently Added Patents
High performance actuator motor
Para-xylylene based microfilm elution devices
Method and apparatus for laser strip splicing
Dental plier
System for targeted delivery of therapeutic agents
Content display monitor
Inspection tool for top guides of a boiling water reactor
  Randomly Featured Patents
Artificial reef module
Method and apparatus for drawing characters which draws curved segments based on approximate points
Method of making a thermocouple and so-made thermocouple
Utility knife
Method of forming integrated CMP stopper and analog capacitor
Computer enclosure
System and method for detection of rotor eccentricity baseline shift
Toner level sensor
Continuous process for making polymers having pendant azlactone or macromolecular moieties
Anticorrosion primer coating composition