Resources Contact Us Home
Conjugates of a polypeptide and a pentasaccharide

Image Number 19 for United States Patent #8106007.

The present invention relates to conjugates of a polypeptide and an oligosaccharide, wherein the polypeptide is conjugated to at least one oligosaccharide-spacer residue, the oligosaccharide being a synthetic sulfated oligosaccharide comprising 4-18 monosaccharide units and per se having affinity to antithrombin III and the spacer being a bond or an essentially pharmacologically inactive flexible linking residue, or a pharmaceutically acceptable salt thereof. The conjugates of the invention have improved pharmacokinetic properties when compared to the original polypeptides (i.e. the corresponding non-conjugated polypeptides per se).

  Recently Added Patents
Anti-infective agents and uses thereof
Address generation unit for accessing a multi-dimensional data structure in a desired pattern
Dental fillers including a phosphorus containing surface treatment, and compositions and methods thereof
PLL circuit
High performance design rule checking technique
Systems and/or methods for using air/wind power to charge/re-charge vehicle batteries
Method for etched cavity devices
  Randomly Featured Patents
Method of treatment of viral hepatitis C with interferon alpha 5
Method and system for displaying an analog image by a digital display device
Information processing device, program developing device, program verifying method, and program product
Automatic kinescope bias control circuit
Organic light emitting display device and fabricating method thereof
On-off valve for a gas injection system, particularly of methane, for internal combustion engines
Image forming apparatus and a method of cleaning photosensitive drum surface
Methods and systems for providing wireless network services
Method and apparatus for remote monitoring of valves and valve operators
Silver halide photographic emulsion and process for preparing the same