Resources Contact Us Home
Conjugates of a polypeptide and a pentasaccharide

Image Number 19 for United States Patent #8106007.

The present invention relates to conjugates of a polypeptide and an oligosaccharide, wherein the polypeptide is conjugated to at least one oligosaccharide-spacer residue, the oligosaccharide being a synthetic sulfated oligosaccharide comprising 4-18 monosaccharide units and per se having affinity to antithrombin III and the spacer being a bond or an essentially pharmacologically inactive flexible linking residue, or a pharmaceutically acceptable salt thereof. The conjugates of the invention have improved pharmacokinetic properties when compared to the original polypeptides (i.e. the corresponding non-conjugated polypeptides per se).

  Recently Added Patents
Glycosylated antibodies
Mixed voltage non-volatile memory integrated circuit with power saving
Expression and export of angiogenesis inhibitors as immunofusins
Salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-- naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one
Electronic timepiece and time adjustment method for an electronic timepiece
Image contrast enhancement in depth sensor
Synchronization of video input data streams and video output data streams
  Randomly Featured Patents
Guide and control means for diaphragm
All-surface biasable and/or temperature-controlled electrostatically-shielded RF plasma source
Foldable container
Transfer apparatus for a refill container
Processing apparatus including a reactor for electrochemically etching microelectronic workpiece
Cosmetic crayon
Segmented rotatable nozzles
Secure authenticated distance measurement
Method and apparatus for installing a large, planar, delicate membrane in an electrolysis cell
Gasoline sulfur reduction in fluid catalytic cracking