Resources Contact Us Home
Conjugates of a polypeptide and a pentasaccharide

Image Number 19 for United States Patent #8106007.

The present invention relates to conjugates of a polypeptide and an oligosaccharide, wherein the polypeptide is conjugated to at least one oligosaccharide-spacer residue, the oligosaccharide being a synthetic sulfated oligosaccharide comprising 4-18 monosaccharide units and per se having affinity to antithrombin III and the spacer being a bond or an essentially pharmacologically inactive flexible linking residue, or a pharmaceutically acceptable salt thereof. The conjugates of the invention have improved pharmacokinetic properties when compared to the original polypeptides (i.e. the corresponding non-conjugated polypeptides per se).

  Recently Added Patents
Ice data collection system
Handheld electronic device with text disambiguation employing advanced editing feature
Buffering stop structure and corresponding packing case
Semiconductor device
Methods of isolating bipotent hepatic progenitor cells
Lens barrel and imaging device
Respirator belt having bumper cushion
  Randomly Featured Patents
Serial input/output circuit with an automatic transfer function
Method and device for evaluating the driving style of a driver in a motor vehicle with respect to the use of fuel
Bicycle front fork protector
Method for manufacturing rigid-flexible printed circuit board
Adaptive pilot structure to assist channel estimation in spread spectrum systems
Relating to freezing apparatus
Constant velocity fixed joint having crossed raceways, universal joint shaft and method for producing a constant velocity fixed joint having crossed raceways
Inbred Maize Variety PHHEP
Development apparatus with magnetically rotated skive
Mercury control activated carbon management