Resources Contact Us Home
Conjugates of a polypeptide and a pentasaccharide

Image Number 19 for United States Patent #8106007.

The present invention relates to conjugates of a polypeptide and an oligosaccharide, wherein the polypeptide is conjugated to at least one oligosaccharide-spacer residue, the oligosaccharide being a synthetic sulfated oligosaccharide comprising 4-18 monosaccharide units and per se having affinity to antithrombin III and the spacer being a bond or an essentially pharmacologically inactive flexible linking residue, or a pharmaceutically acceptable salt thereof. The conjugates of the invention have improved pharmacokinetic properties when compared to the original polypeptides (i.e. the corresponding non-conjugated polypeptides per se).

  Recently Added Patents
Vaccination with killed but metabolically active (KBMA) protozoans with toll-like receptor agonists
Hot-press cushion material and manufacturing method of the same
Metal colloidal particles, metal colloid and use of metal colloid
Proximity-based mobile message delivery
Power transmission control device for vehicle
Pear tree named `PremP109`
Decision management system and method
  Randomly Featured Patents
Rubberized coal tar pitch emulsion
Strip electrode for overlay welding
Photomask and method for fabricating the same
Tape composition and process for internally constrained sintering of low temperature co-fired ceramic
Motorhome with increased interior ceiling height
Thermally insulated garment with displaceable feet-enclosing sections
N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines
Anti-copy system utilizing audible and inaudible protection signals
Method and module for modifying speech model by different speech sequence
Candle holder