Resources Contact Us Home
Conjugates of a polypeptide and a pentasaccharide

Image Number 16 for United States Patent #8106007.

The present invention relates to conjugates of a polypeptide and an oligosaccharide, wherein the polypeptide is conjugated to at least one oligosaccharide-spacer residue, the oligosaccharide being a synthetic sulfated oligosaccharide comprising 4-18 monosaccharide units and per se having affinity to antithrombin III and the spacer being a bond or an essentially pharmacologically inactive flexible linking residue, or a pharmaceutically acceptable salt thereof. The conjugates of the invention have improved pharmacokinetic properties when compared to the original polypeptides (i.e. the corresponding non-conjugated polypeptides per se).

  Recently Added Patents
Illuminating waveguide fabrication method
Low cost mesh network capability
Non-volatile memory cell containing a nano-rail electrode
Secure service for enabling communication for calling party when communication service for called party is suspended
Two dimensional magnetic sensor immune to skew angle misalignment
Position-measuring device
Multi charged particle beam writing apparatus and multi charged particle beam writing method
  Randomly Featured Patents
Method and apparatus for image reproduction
Coated part, coating and method of coating
Plate for fluid-bed reactors
Apparatus for transmitting and receiving MPEG data by using wireless LAN
Video signal receiving system with signal source switching based on generated control signals
Nitrogenous additives with an antioxidant action and lubricating compositions containing the said additives
Ag base sputtering target and process for producing the same
Data outputting circuit for semiconductor memory device
Telephone enclosure