Resources Contact Us Home
Conjugates of a polypeptide and a pentasaccharide

Image Number 16 for United States Patent #8106007.

The present invention relates to conjugates of a polypeptide and an oligosaccharide, wherein the polypeptide is conjugated to at least one oligosaccharide-spacer residue, the oligosaccharide being a synthetic sulfated oligosaccharide comprising 4-18 monosaccharide units and per se having affinity to antithrombin III and the spacer being a bond or an essentially pharmacologically inactive flexible linking residue, or a pharmaceutically acceptable salt thereof. The conjugates of the invention have improved pharmacokinetic properties when compared to the original polypeptides (i.e. the corresponding non-conjugated polypeptides per se).

  Recently Added Patents
Cooling method and device for cooling a medium-voltage electrical installation in a protective sheath
Optical packet signal transmission device and WDM optical communication network
Data processing circuit with arbitration between a plurality of queues
Implantable medical devices including elongated conductor bodies that facilitate device and lead configuration variants
Communication apparatus, communication method, and program for exchanging data with a target
Method and system for providing cloud based network security services
Methods and compositions for inhibition of neutrophil exocytosis
  Randomly Featured Patents
Grabbing device and method for controlling the gripping force
Universal centrifuge
Computer housing front panel
Cable wrap security device
Connector assembly for a photoelectric sensor
Cationic amphiphiles for intracellular delivery of therapeutic molecules
Method of image mensuration with selectively visible and invisible reseau grid marks
Multi-chip electronic package having laminate carrier and method of making same
Photovoltaic element having a transparent conductive layer with specified fractal dimension and fractal property
Pneumatic tire