Resources Contact Us Home
Antibodies blocking fibroblast growth factor receptor activation and methods of use thereof

Image Number 5 for United States Patent #8101721.

The present invention is related to antibodies with binding affinity to fibroblast growth factor receptor 2 (FGFR2) optionally with binding affinity to other FGF receptors, which block both ligand-dependent and constitutive ligand independent receptor activation. Specifically, the present invention relates to antibodies with high affinity to more than one FGF receptor subtype, and fragments thereof, useful in treating disorders including cell proliferative diseases.

  Recently Added Patents
Tap initialization of equalizer based on estimated channel impulse response
Optical article comprising a temporary anti-fogging coating with improved durability
Subpixel-based image down-sampling
System for non-destructive image processing
Inductive antenna coupling
Method and system for coding an information signal using closed loop adaptive bit allocation
Compositions of PD-1 antagonists and methods of use
  Randomly Featured Patents
Trimodal exercise apparatus
Expandable piston rotary machine
Method and apparatus for detecting the presence of fluids
Power line induction of sheath test current to discover defective coaxial cable
Method for immobilizing nucleic acid molecules
Weatherable, thermostable polymers having improved flow composition
Endoscopic tissue apposition device with multiple suction ports
Cushioning plate assembly of a clutch disc
Semiconductor fabrication employing self-aligned sidewall spacers laterally adjacent to a transistor gate