Resources Contact Us Home
Monoclonal antibody to CD166 and method for production thereof

Image Number 2 for United States Patent #8003762.

CD166 is a cell adhesion molecule belonging to an immunoglobulin superfamily that is expressed in an excessive amount on the tumor surface. If an monoclonal antibody specifically binding to the CD166 is obtained, it becomes possible to suppress growth of tumor cells, detect the cells, and supply a therapeutic drug thereto specifically. However, because the CD166 proteins are very similar to each other among mammals, it was not possible to obtain an antibody to human CD166, by immunizing, for example, mice with the human CD166. The antibody was prepared by immunizing mice with a purified avian CD166 protein. The antibody was found to be adsorbed on human and mouse CD166 proteins in vitro as well as in vivo and to have an action to suppress tumor growth in mice.

  Recently Added Patents
Image signal processing apparatus and image signal processing method
Image processing unit, image processing method and program
Image heating apparatus
Systems and methods for automobile accident claims initiation
Semiconductor element-embedded wiring substrate
Controller interface providing improved data reliability
Correction information calculating device, image processing apparatus, image display system, and image correcting method
  Randomly Featured Patents
Method for determining volume of organic matter in reservoir rock
Reference circuit for supplying a reference level for sensing in a memory
Neutral pH freezer bar and process
Putter head
Self-adjusting clutch mechanism
Tire tread
Electrical connector
Seat belt retractor
Garment with retractable fringes
Method for production of high solids silicone resin coating solution