Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Monoclonal antibody to CD166 and method for production thereof










Image Number 2 for United States Patent #8003762.

CD166 is a cell adhesion molecule belonging to an immunoglobulin superfamily that is expressed in an excessive amount on the tumor surface. If an monoclonal antibody specifically binding to the CD166 is obtained, it becomes possible to suppress growth of tumor cells, detect the cells, and supply a therapeutic drug thereto specifically. However, because the CD166 proteins are very similar to each other among mammals, it was not possible to obtain an antibody to human CD166, by immunizing, for example, mice with the human CD166. The antibody was prepared by immunizing mice with a purified avian CD166 protein. The antibody was found to be adsorbed on human and mouse CD166 proteins in vitro as well as in vivo and to have an action to suppress tumor growth in mice.








 
 
  Recently Added Patents
Image forming apparatus forming images in response to image formation request from operation unit or external device
Intrinsic absorber layer for photovoltaic cells
Press nut
Transfer formulas
Disk drive to enable defect margining
Memory elements with increased write margin and soft error upset immunity
SRAM cells using shared gate electrode configuration
  Randomly Featured Patents
Lysine binding fragments of angiostatin
Drawing-blowing method and device for molding thermoplastic material containers, in particular bottles, with petaloid bottoms
Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles
Image processing apparatus using alpha plane and method thereof
High brightness optical device
Protected optical fiber cable and hydrogen gettering agent
Motor car
Information communication system, information communication method, node device included in information communication system and recording medium recording information processing program
Forward error correction (FEC) for packetized data networks
Process for producing isocyanurates by cyclotrimerizing isocyanates using polymer-bound catalysts