Resources Contact Us Home
Monoclonal antibody to CD166 and method for production thereof

Image Number 2 for United States Patent #8003762.

CD166 is a cell adhesion molecule belonging to an immunoglobulin superfamily that is expressed in an excessive amount on the tumor surface. If an monoclonal antibody specifically binding to the CD166 is obtained, it becomes possible to suppress growth of tumor cells, detect the cells, and supply a therapeutic drug thereto specifically. However, because the CD166 proteins are very similar to each other among mammals, it was not possible to obtain an antibody to human CD166, by immunizing, for example, mice with the human CD166. The antibody was prepared by immunizing mice with a purified avian CD166 protein. The antibody was found to be adsorbed on human and mouse CD166 proteins in vitro as well as in vivo and to have an action to suppress tumor growth in mice.

  Recently Added Patents
Coordinated garbage collection for raid array of solid state disks
Method of transmitting and receiving wireless resource information
Electric separator, method for the production and use thereof
Lightning-protective explosion-preventive fastener
Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual
  Randomly Featured Patents
Relay device and relay method
Field emission electron source and fabrication process thereof
Method of forming wiring of a semiconductor memory device
Method and apparatus for coding/decoding image signal providing accurate determination of an image contour and efficient compression coding
Switch-type imaging fiber apparatus and branch-type imaging fiber apparatus
Method of manufacturing semiconductor device
Method and apparatus for producing information regarding the operation of a networked system
Base for a kitchen appliance
Methods and apparatus for prioritizing assignment of a packet data session for a plurality of applications of a mobile communication device
Daylily named `Rosy Returns`