Resources Contact Us Home
Monoclonal antibody to CD166 and method for production thereof

Image Number 2 for United States Patent #8003762.

CD166 is a cell adhesion molecule belonging to an immunoglobulin superfamily that is expressed in an excessive amount on the tumor surface. If an monoclonal antibody specifically binding to the CD166 is obtained, it becomes possible to suppress growth of tumor cells, detect the cells, and supply a therapeutic drug thereto specifically. However, because the CD166 proteins are very similar to each other among mammals, it was not possible to obtain an antibody to human CD166, by immunizing, for example, mice with the human CD166. The antibody was prepared by immunizing mice with a purified avian CD166 protein. The antibody was found to be adsorbed on human and mouse CD166 proteins in vitro as well as in vivo and to have an action to suppress tumor growth in mice.

  Recently Added Patents
Analogue-to-digital converter
Multi-level integrated circuit, device and method for modeling multi-level integrated circuits
Switchable solvents and methods of use thereof
Sample chamber for laser ablation inductively coupled plasma mass spectroscopy
Apparatus for touch screen avionic device
Sensing during magnetic resonance imaging
Method of predicting a motion vector for a current block in a current picture
  Randomly Featured Patents
Single use syringe
Manufacturing method of semiconductor device
Method and apparatus for clarifying liquids
Compressed fabric article package having a butterfly shape
Spark timing control device for internal combustion engine
Guitar or the like
Electric-based secondary power system architectures for aircraft
5-pyrimidinecarboxyamides and treatment of leukemia therewith
Microwave moisture sensing arrangement
Codec-independent technique for modulating bandwidth in packet network