Resources Contact Us Home
Monoclonal antibody to CD166 and method for production thereof

Image Number 2 for United States Patent #8003762.

CD166 is a cell adhesion molecule belonging to an immunoglobulin superfamily that is expressed in an excessive amount on the tumor surface. If an monoclonal antibody specifically binding to the CD166 is obtained, it becomes possible to suppress growth of tumor cells, detect the cells, and supply a therapeutic drug thereto specifically. However, because the CD166 proteins are very similar to each other among mammals, it was not possible to obtain an antibody to human CD166, by immunizing, for example, mice with the human CD166. The antibody was prepared by immunizing mice with a purified avian CD166 protein. The antibody was found to be adsorbed on human and mouse CD166 proteins in vitro as well as in vivo and to have an action to suppress tumor growth in mice.

  Recently Added Patents
Apparatus and method for categorizing services using canonical service descriptions
Systems and/or methods for determining item serial number structure and intelligence
Method for olympic event hospitality program management
Method and system for billing based on color component histograms
Distributed IP-PBX signal processing
Socket type MEMS device with stand-off portion
Permanent magnet rotor with flux concentrating pole pieces
  Randomly Featured Patents
Dual damascene
Combined engine analyzer and cart
Educational writing board kit
Ion exchange removal of metal ions from wastewater
High withstand voltage Darlington transistor circuit
Main body of image scanner apparatus
Stretchable strap with gripper and method of making the same
Multiple input/multiple output communication method based on distributed transmission sources
Circuit breaker interface mechanism for bell alarm switch