Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Monoclonal antibody to CD166 and method for production thereof










Image Number 2 for United States Patent #8003762.

CD166 is a cell adhesion molecule belonging to an immunoglobulin superfamily that is expressed in an excessive amount on the tumor surface. If an monoclonal antibody specifically binding to the CD166 is obtained, it becomes possible to suppress growth of tumor cells, detect the cells, and supply a therapeutic drug thereto specifically. However, because the CD166 proteins are very similar to each other among mammals, it was not possible to obtain an antibody to human CD166, by immunizing, for example, mice with the human CD166. The antibody was prepared by immunizing mice with a purified avian CD166 protein. The antibody was found to be adsorbed on human and mouse CD166 proteins in vitro as well as in vivo and to have an action to suppress tumor growth in mice.








 
 
  Recently Added Patents
Method and apparatus for radio antenna frequency tuning
Non-zero rounding and prediction mode selection techniques in video encoding
Methods for measuring media performance associated with adjacent track interference
Selecting modulation and coding scheme in the presence of interference
System and method for outputting virtual textures in electronic devices
Stool
Content display system
  Randomly Featured Patents
Sight eye marksmanship training aid
As-deposited oxide superconductor films on silicon and aluminum oxide
Upper for an athletic shoe and method for manufacturing the same
Auxiliary drive for a trailer
Clearance measurement systems and methods of operation
Method of preparing a cryoprecipitated suspension and use thereof
Corrosion inhibitors of steels and aqueous compositions of alkali meal halide containing them
Figure location detecting system
Random access memory device capable of minimizing sensing noise
Cooling system for automotive engine or the like