Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Monoclonal antibody to CD166 and method for production thereof










Image Number 2 for United States Patent #8003762.

CD166 is a cell adhesion molecule belonging to an immunoglobulin superfamily that is expressed in an excessive amount on the tumor surface. If an monoclonal antibody specifically binding to the CD166 is obtained, it becomes possible to suppress growth of tumor cells, detect the cells, and supply a therapeutic drug thereto specifically. However, because the CD166 proteins are very similar to each other among mammals, it was not possible to obtain an antibody to human CD166, by immunizing, for example, mice with the human CD166. The antibody was prepared by immunizing mice with a purified avian CD166 protein. The antibody was found to be adsorbed on human and mouse CD166 proteins in vitro as well as in vivo and to have an action to suppress tumor growth in mice.








 
 
  Recently Added Patents
Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
Controller interface providing improved data reliability
Adjustable high precision surveying device
Codeword-enhanced peer-to-peer authentication
Wafer level packaging
Storage apparatus and method including page discard processing for primary and secondary volumes configured as a copy pair
Radio link monitoring (RLM) and reference signal received power (RSRP) measurement for heterogeneous networks
  Randomly Featured Patents
Valve construction and method of making the same
Surfactant-containing insulation binder
Method for enhancing mutant enzyme activity in gaucher disease
Headlight for vehicles with reflector adjusting device
Reed capsule
Soybean cultivar S080193
Burn-in control
Laminated sponge device
Process for reducing particle defects in arc vapor deposition coatings
Method and apparatus for measuring blood volume, and vital sign monitor using the same