Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Clostridium perfringens alpha toxin proteins










Image Number 6 for United States Patent #7982006.

This invention pertains in part to the development of a vaccine for poultry against necrotic enteritis (NE). The vaccine utilizes a protective antigen that is a mutated, full-length, non-toxic Clostridium perfringens (Cp) .alpha.-toxin protein (Mcpa). Utility of this vaccine was demonstrated by reduction of lesion severity in NE challenge trails, for example. Also disclosed herein are novel approaches for producing this vaccine in significant quantities. One exemplified approach involves producing NE vaccine (mutated alpha toxin) in bacterial expression systems, preferably utilizing the Pseudomonas fluorescens system, for commercial use in controlling NE in the poultry industry. The subject vaccines can be administered preferably to chickens in several different ways. A novel, Type VI alpha toxin from chicken isolates of Cp is also disclosed.








 
 
  Recently Added Patents
Glove
Interaction analysis and prioritization of mobile content
Electron beam manipulation system and method in X-ray sources
Double patterning method using tilt-angle deposition
Method and system of channel detecting and reporting, terminal, and management center
Autobrake and decel control built-in test equipment
Blue box
  Randomly Featured Patents
Coating and bonding composition
System for mounting a device to a host
Ensuring referential integrity when using WebDAV for distributed development of a complex software application
Power interface circuit of contact IC card reader
Radar device
Clutch driven plate assembly with a floating hub
Method for cleaning a sand screen
Band clamp
Thio-oxindole derivatives
Response and data phases in a highly pipelined bus architecture