Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Clostridium perfringens alpha toxin proteins










Image Number 6 for United States Patent #7982006.

This invention pertains in part to the development of a vaccine for poultry against necrotic enteritis (NE). The vaccine utilizes a protective antigen that is a mutated, full-length, non-toxic Clostridium perfringens (Cp) .alpha.-toxin protein (Mcpa). Utility of this vaccine was demonstrated by reduction of lesion severity in NE challenge trails, for example. Also disclosed herein are novel approaches for producing this vaccine in significant quantities. One exemplified approach involves producing NE vaccine (mutated alpha toxin) in bacterial expression systems, preferably utilizing the Pseudomonas fluorescens system, for commercial use in controlling NE in the poultry industry. The subject vaccines can be administered preferably to chickens in several different ways. A novel, Type VI alpha toxin from chicken isolates of Cp is also disclosed.








 
 
  Recently Added Patents
Portable stand for computer
High brightness laser diode module
Screen
Playlist search device, playlist search method and program
Conductive polymer and a solid electrolytic capacitor using the same as a solid electrolyte
Methods and apparatus for mitigating interference between co-located collaborating radios
Coordinated multi-point transmission in a cellular network
  Randomly Featured Patents
Sequential deposition process for gap filling
Ultrasound echogenic cardiac lead
Dual range countershaft transmission
Treatment or prophylaxis of diseases caused by pilus-forming bacteria
Nematode fatty acid desaturase-like sequences
Support spacer
Gas generator for a safety system
Device and method for operating a high-pressure discharge lamp
File content display device, file content display method, and computer program therefore
Bracing mechanism and method for securing loading platforms