Resources Contact Us Home
Clostridium perfringens alpha toxin proteins

Image Number 10 for United States Patent #7982006.

This invention pertains in part to the development of a vaccine for poultry against necrotic enteritis (NE). The vaccine utilizes a protective antigen that is a mutated, full-length, non-toxic Clostridium perfringens (Cp) .alpha.-toxin protein (Mcpa). Utility of this vaccine was demonstrated by reduction of lesion severity in NE challenge trails, for example. Also disclosed herein are novel approaches for producing this vaccine in significant quantities. One exemplified approach involves producing NE vaccine (mutated alpha toxin) in bacterial expression systems, preferably utilizing the Pseudomonas fluorescens system, for commercial use in controlling NE in the poultry industry. The subject vaccines can be administered preferably to chickens in several different ways. A novel, Type VI alpha toxin from chicken isolates of Cp is also disclosed.

  Recently Added Patents
Systems and/or methods for using air/wind power to charge/re-charge vehicle batteries
Lens module and method for manufacturing thereof
Eye therapy system
Pressure-sensitive adhesive composition having an improved release behavior
Communication system including relay station and data frame for the communication system
Upper surface of a skateboard deck
Power converter for an LED assembly and lighting application
  Randomly Featured Patents
Drag reduction fairing
Method of playing a poker-type wagering game
Self adjusting construction tie-down
LED drive circuit
Integrated circuit device formed with high Q MIM capacitor
Device for receiving a transmission signal and for transmitting an optical beam and method of using the device
Thin-film magnetic head and method of making where the head includes an antireflection film covering a leading shield
Loyalty link method and apparatus with audio performance for integrating customer information with dealer management information
Storage retrieval system
Portion of a motor grader