Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Clostridium perfringens alpha toxin proteins










Image Number 10 for United States Patent #7982006.

This invention pertains in part to the development of a vaccine for poultry against necrotic enteritis (NE). The vaccine utilizes a protective antigen that is a mutated, full-length, non-toxic Clostridium perfringens (Cp) .alpha.-toxin protein (Mcpa). Utility of this vaccine was demonstrated by reduction of lesion severity in NE challenge trails, for example. Also disclosed herein are novel approaches for producing this vaccine in significant quantities. One exemplified approach involves producing NE vaccine (mutated alpha toxin) in bacterial expression systems, preferably utilizing the Pseudomonas fluorescens system, for commercial use in controlling NE in the poultry industry. The subject vaccines can be administered preferably to chickens in several different ways. A novel, Type VI alpha toxin from chicken isolates of Cp is also disclosed.








 
 
  Recently Added Patents
Efficient relay automatic repeat request procedure in broadband wireless access system
Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom
Managing imaging of computing devices
Communication device and method for detecting a radio signal
Processing autocomplete suggestions
Die packages and systems having the die packages
Secure service for enabling communication for calling party when communication service for called party is suspended
  Randomly Featured Patents
Magnetic disk drive having a VCM plate which includes an elongated protrusion for securing a flex clamp to the base
Method for planarizing a substrate of a liquid crystal display
System and method of automating multidimensional scaling for psychophysics
Optical fiber with polymeric coating crosslinked in the presence of both radical and cationic photoinitiators
Copy sheet purge processing device
Lipophillically-substituted piperidine oxadiazolyl compounds and their use in stimulating cognitive functions
Closed circuit breathing apparatus and method of using same
Door drive with a chain
Learning-type movement control apparatus, method therefor, and distribution medium therefor
Asphalt paver