Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Clostridium perfringens alpha toxin proteins










Image Number 10 for United States Patent #7982006.

This invention pertains in part to the development of a vaccine for poultry against necrotic enteritis (NE). The vaccine utilizes a protective antigen that is a mutated, full-length, non-toxic Clostridium perfringens (Cp) .alpha.-toxin protein (Mcpa). Utility of this vaccine was demonstrated by reduction of lesion severity in NE challenge trails, for example. Also disclosed herein are novel approaches for producing this vaccine in significant quantities. One exemplified approach involves producing NE vaccine (mutated alpha toxin) in bacterial expression systems, preferably utilizing the Pseudomonas fluorescens system, for commercial use in controlling NE in the poultry industry. The subject vaccines can be administered preferably to chickens in several different ways. A novel, Type VI alpha toxin from chicken isolates of Cp is also disclosed.








 
 
  Recently Added Patents
High gradient lens for charged particle beam
Systems and methods for mitigating spectral regrowth from non-linear systems
Image forming apparatus, information processing method, and storage medium for generating screen information
Cartridge for conducting a chemical reaction
Selective thermal treatment of medical instrument portions with thermal treatment system instrument holder
Therapeutic human anti-IL-1R1 monoclonal antibody
Bioactive agent-loaded heart-targeting nanoparticles
  Randomly Featured Patents
Water treating method, water treating apparatus, and hydroponics system using the apparatus
Low cost coaxial cable connection for wireless antennas
Camshaft and a method and a device for producing the same
Method and apparatus for determining plant water content
System for fault determinations for high frequency electronic circuits
Motor controller having a multifunction port
System and method for QoS support in ubiquitous sensor
Method of subjecting a protein-containing material to flash flow processing and product thereof
Retractable blade cutting apparatuses and methods for mowing machines
Hexa-arm polyethylene glycol and its derivatives and the methods of preparation thereof