Resources Contact Us Home
Derivatives of 4- or 5-aminosalicylic acid

Image Number 16 for United States Patent #7879827.

The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention/treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention/treatment of colon cancer.

  Recently Added Patents
Electrowetting display devices with a reflective plate structure
Polyolefin and composition for pipe systems and sheets
Cosmetic/dermatological compositions comprising naphthoic acid compounds and polyurethane polymers
Egg separator
Measuring device and measuring method that use pulsed electromagnetic wave
Lightweight multicast method and apparatus for data distribution service
Organic compounds
  Randomly Featured Patents
Eye opening monitor
Protein tyrosine phosphatase inhibitors
Surgical instrument for manipulating a thread
Digital-imaging based code symbol reading system employing a plurality of coplanar illumination and imaging subsystems, global object motion detection subsystem for automatically detecting obj
Foaming cosmetic compositions
Work clamp for woodworking machines
Digital-to-analog converter circuit, data driver, and display device using the digital-to-analog converter circuit
Machine vise
Method of storing a sleeping bag with a clinching mechanism
Overvoltage protectors sealed with gel