Resources Contact Us Home
Derivatives of 4- or 5-aminosalicylic acid

Image Number 16 for United States Patent #7879827.

The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention/treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention/treatment of colon cancer.

  Recently Added Patents
Constant low-flow air source control system and method
Hybrid interconnect scheme including aluminum metal line in low-k dielectric
LED lamp including heat dissipator
Image forming apparatus capable of timely starting different image formation mode
Signal processor and signal processing method
Low temperature pressure chamber unit, magnetic resonance device with a low temperature pressure chamber unit, and an attachment method to attach at least one add-on unit to an external housin
Semiconductor device having a triple gate transistor and method for manufacturing the same
  Randomly Featured Patents
Optical device for projection of optical beams
Method and apparatus for differentiating antegrade from retrograde P-waves and for preventing pacemaker generated tachycardia
Method of constructing a tube bundle
Apparatus using oscillating rotating pistons
Fast cell search and accurate synchronization in wireless communications
Apparatus for retrofitting an existing door to provide a fire rating to the unrated existing door
Three-dimensional fabrication
Magnetostatic wave delay line having improved group delay linearity