Resources Contact Us Home
Derivatives of 4- or 5-aminosalicylic acid

Image Number 16 for United States Patent #7879827.

The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention/treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention/treatment of colon cancer.

  Recently Added Patents
Process for improving the hydrolysis of cellulose in high consistency systems using one or more unmixed and mixed hydrolysis reactors
Signal processing device and method for providing oscillating signal in the signal processing device
Verification of computer-executable code generated from a model
Devices, systems, and methods for tactile feedback and input
Point-in-time copies in a cascade using maps and fdisks
File management apparatus and file management apparatus controlling method
Image forming apparatus, control method of image forming apparatus, and storage medium
  Randomly Featured Patents
Lightweight engine poppet valve
Device for damping the closing movement of a dual door spring-loaded or closure and closure control therefor
Photographic product comprising a blend of emulsions with different sensitivities
Methods of utilizing waste waters produced by water purification processing
Catheter for angiography
Self-locking braking device for rotary shafts, and relevant applications
Battery charger with active feedback voltage controller
Power unit and image forming apparatus provided with same mounted thereto
Information processing in which grouped information is processed either as a group or individually, based on mode
Method for treating meat products with ammonia