Resources Contact Us Home
Derivatives of 4- or 5-aminosalicylic acid

Image Number 16 for United States Patent #7879827.

The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention/treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention/treatment of colon cancer.

  Recently Added Patents
Systems and methods for tracking power modulation
Polymer bonded fibrous coating on dipped rubber articles skin contacting external surface
Wavelength and power scalable waveguiding-based infrared laser system
Method and system of channel detecting and reporting, terminal, and management center
Surround sound effects provided by cell phones
Communication system including a switching section for switching a network route, controlling method and storage medium
  Randomly Featured Patents
System and method for halftoning using a time-variable halftone pattern
Gas chromatograph sample injector
File system for filing documents, using a catalog card having a plurality of marks thereon
Apparatus for guiding and steering earth boring casing
Liquid crystal display device and fabricating method thereof, and reworking method of alignment film using the same
Vapor or gas detector and alarm system
Plural extruder method for making a composite building panel
Reactive dyes having a sulphonamido group
Multifunction solid state laser system
Cell search method for mobile station in mobile communication system and mobile station