Resources Contact Us Home
Derivatives of 4- or 5-aminosalicylic acid

Image Number 16 for United States Patent #7879827.

The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention/treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention/treatment of colon cancer.

  Recently Added Patents
Data communication apparatus, method of controlling the same, program, and storage medium
Acrylic pressure-sensitive adhesive composition, acrylic pressure-sensitive adhesive layer, and acrylic pressure-sensitive adhesive tape
Luminescent nanosheets, and fluorescent illuminators, solar cells and color displays utilizing the same as well as nanosheet paints
Electrical connector
Image forming apparatus to automatically select a communication condition
Systems and methods for providing a shared folder via television
Multi-radio coexistence
  Randomly Featured Patents
Bidet apparatus for use in connection with a conventional flush toilet
Embedded reactive and proactive intelligence
Decomposition of networking device configuration into versioned pieces each conditionally applied depending on external circumstances
Disk drive suspension having a recess in a load beam or baseplate to contain damping material, and a lid portion for the recess formed by a plate-like constituent member of the suspension
Controller and actuating system for surgical instrument
Standard cell layout arrangement for an LSI circuit
Product development system and method using integrated process and data management
Method for making planar optical waveguides
Wedge-base lamp and socket assembly
Disposable eye patch and method of manufacturing a disposable eye patch