Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Purine derivatives as A3 and A1 adenosine receptor agonists










Image Number 5 for United States Patent #7825126.

Disclosed are (N)-methanocarba adenine nucleosides of the formula: ##STR00001## as highly potent A.sub.3 adenosine receptor agonists, pharmaceutical compositions comprising such nucleosides, and a method of use of these nucleosides, wherein R.sub.1-R.sub.6 are as defined in the specification. These nucleosides are contemplated for use in the treatment a number of diseases, for example, inflammation, cardiac ischemia, stroke, asthma, diabetes, and cardiac arrhythmias. The invention also provides compounds that are agonists of both A.sub.1 and A.sub.3 adenosine receptors for use in cardioprotection.








 
 
  Recently Added Patents
Cell surface display, screening and production of proteins of interest
Video reproducing apparatus and video reproducing method
Information obtaining and notification, data message forwarding and handover method and access node
Method and apparatus for image sensor packaging
System and method for backup communication over ethernet
Method of reducing acetaldehyde in polyesters, and polyesters therefrom
Resource compatability for data centers
  Randomly Featured Patents
Methods and apparatus for making liposomes containing hydrophobic drugs
Photoconductive polymer and method of manufacture
Configurable internal/external linear voltage regulator
Shaving razor tray
Upper coupling attachment for MacPherson strut
Control arrangement for automatic vending machine
2-Decarboxy-2-aminomethyl-19-hydroxy-19-methyl-6a-carba-PGI.sub.2 compounds
Catalyst component for ethylene polymerization, the preparation thereof and catalyst comprising the same
Cable termination assembly, nipping and knuckling machine, and method
Token configured to interact