Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Purine derivatives as A3 and A1 adenosine receptor agonists










Image Number 5 for United States Patent #7825126.

Disclosed are (N)-methanocarba adenine nucleosides of the formula: ##STR00001## as highly potent A.sub.3 adenosine receptor agonists, pharmaceutical compositions comprising such nucleosides, and a method of use of these nucleosides, wherein R.sub.1-R.sub.6 are as defined in the specification. These nucleosides are contemplated for use in the treatment a number of diseases, for example, inflammation, cardiac ischemia, stroke, asthma, diabetes, and cardiac arrhythmias. The invention also provides compounds that are agonists of both A.sub.1 and A.sub.3 adenosine receptors for use in cardioprotection.








 
 
  Recently Added Patents
DC/DC converter, power supply circuit, and semiconductor device
Process for producing a carbon-comprising support
Systems, methods, and media for firewall control via remote system information
Agents for preventing and treating disorders involving modulation of the ryanodine receptors
Monitoring agent programs in a distributed computing platform
Plants and seeds of hybrid corn variety CH514730
Adding value to a rendered document
  Randomly Featured Patents
Aerosol container cap
Method and apparatus for cooling a hybrid transmission electric motor
Method of fabricating nano-structured surface and configuration of surface enhanced light scattering probe
Image signature creating method and apparatus for discriminating still images
Hydrogenation of esters or carbonyl groups with tetradentate amino/imino-thioether based ruthenium complexes
Memory module connector with latch assist
Sealing ring having circular-cylindrical inner surface and flat side surfaces with connecting transition surfaces leading to rounded outer surface
Multi-legged equipment support for cameras, spotting telescopes and the like and jam-plate lock for same
Synchronization of CRT controller chips
Measuring system of transmission characteristics