Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Purine derivatives as A3 and A1 adenosine receptor agonists










Image Number 5 for United States Patent #7825126.

Disclosed are (N)-methanocarba adenine nucleosides of the formula: ##STR00001## as highly potent A.sub.3 adenosine receptor agonists, pharmaceutical compositions comprising such nucleosides, and a method of use of these nucleosides, wherein R.sub.1-R.sub.6 are as defined in the specification. These nucleosides are contemplated for use in the treatment a number of diseases, for example, inflammation, cardiac ischemia, stroke, asthma, diabetes, and cardiac arrhythmias. The invention also provides compounds that are agonists of both A.sub.1 and A.sub.3 adenosine receptors for use in cardioprotection.








 
 
  Recently Added Patents
Method of estimating remaining constant current/constant voltage charging time
Methods and apparatus to identify exposure to 3D media presentations
Integrated circuit packaging system with an integral-interposer-structure and method of manufacture thereof
Wind farm, wind power plant in a wind farm and operating control for this purpose
Vehicle front fender
Nitrogen-doped carbon-supported cobalt-iron oxygen reduction catalyst
Method and apparatus for visual neural stimulation
  Randomly Featured Patents
Proximity monitor
Ablation devices with sensor structures
Cigar travel case
Recyclable pizza box
Apparatus and method for rendering synthetic objects into real scenes using measurements of scene illumination
Apparatus for removing torque ripples in a direct current motor
Fuel injection system
Test structure to monitor the in-situ channel temperature of field effect transistors
Double oven front panel and door
Support device for stationery goods