Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Purine derivatives as A3 and A1 adenosine receptor agonists










Image Number 5 for United States Patent #7825126.

Disclosed are (N)-methanocarba adenine nucleosides of the formula: ##STR00001## as highly potent A.sub.3 adenosine receptor agonists, pharmaceutical compositions comprising such nucleosides, and a method of use of these nucleosides, wherein R.sub.1-R.sub.6 are as defined in the specification. These nucleosides are contemplated for use in the treatment a number of diseases, for example, inflammation, cardiac ischemia, stroke, asthma, diabetes, and cardiac arrhythmias. The invention also provides compounds that are agonists of both A.sub.1 and A.sub.3 adenosine receptors for use in cardioprotection.








 
 
  Recently Added Patents
System and method for interactive image-based modeling of curved surfaces using single-view and multi-view feature curves
Control system for shifting an automatic transmission
Victim port-based design for test area overhead reduction in multiport latch-based memories
Lithographic apparatus and device manufacturing method
Semiconductor device and manufacturing method thereof
Digital media content distribution
Sample chamber for laser ablation inductively coupled plasma mass spectroscopy
  Randomly Featured Patents
7-Substituted-3-vinyl-3-cephem compounds and processes for production of the same
Bottom die construction
Nucleotide sequence encoding soybean vestitone reductase
Globe for roadway luminaire
Pharmaceutically useful pyrazolopyridines
Beer keg tapping closure units
Optical power calibration at the outer edge of an optical storage carrier
Regulation of vertebrate ovarian maturation and function using growth factors
Weight with handles
Image forming apparatus and defective nozzle detection method