Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Purine derivatives as A3 and A1 adenosine receptor agonists










Image Number 5 for United States Patent #7825126.

Disclosed are (N)-methanocarba adenine nucleosides of the formula: ##STR00001## as highly potent A.sub.3 adenosine receptor agonists, pharmaceutical compositions comprising such nucleosides, and a method of use of these nucleosides, wherein R.sub.1-R.sub.6 are as defined in the specification. These nucleosides are contemplated for use in the treatment a number of diseases, for example, inflammation, cardiac ischemia, stroke, asthma, diabetes, and cardiac arrhythmias. The invention also provides compounds that are agonists of both A.sub.1 and A.sub.3 adenosine receptors for use in cardioprotection.








 
 
  Recently Added Patents
Pet cremation urn
Method for processing an algae medium containing algae microorganisms to produce algal oil and by-products
Leadless integrated circuit packaging system and method of manufacture thereof
Bioreactor device, and method and system for fabricating tissues in the bioreactor device
Proximity sensor arrangement in a mobile device
Hydrothermal synthesis of nanocubes of sillenite type compounds for photovoltaic applications and solar energy conversion of carbon dioxide to fuels
Actuators and moveable elements with position sensing
  Randomly Featured Patents
Bone anchor inserter with retractable shield
Gift box
Method and system for monitoring and controlling a single channel per carrier satellite link between two remote earth stations
Process for forming mixed bimetal alkoxide-carboxylate composition and novel compositions thereof
Alkali metal salts of poly(vinylbenzoic acid) as dental plaque barrier agents
Structure and method for linking within a website
Method and apparatus for a verifiable on line rejection of an applicant for credit
Digital imaging method and apparatus for detection of document security marks
Method and apparatus for continuous production of NM cable
Trajectory guide