Resources Contact Us Home
Abuse-resistant amphetamine prodrugs

Image Number 14 for United States Patent #7662788.

The invention describes compounds, compositions, and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

  Recently Added Patents
Transparent zebrafish and preparation method thereof
System and method for interactive image-based modeling of curved surfaces using single-view and multi-view feature curves
Printing control method and printer for printing on a label
Wireless communications apparatus and wireless communications method
Method and system for automatically hiding irrelevant parts of hierarchical structures in computer user interfaces
Bad column management with bit information in non-volatile memory systems
Method and device for monitoring and analyzing signals
  Randomly Featured Patents
Absorbent article having containment gaskets
Ballast block deck system and pedestal assembly therefor
Gaillardia plant named `DGAL906`
Multiple irradiation effect-corrected dose determination technique for charged particle beam lithography
IR imaging with surface wave readout
Graphic processing apparatus
Optical recording medium having relationship between pit depths, wavelength and refractive index
Heating element
Activated depollution boom
Tent structure