Resources Contact Us Home
Abuse-resistant amphetamine prodrugs

Image Number 12 for United States Patent #7662788.

The invention describes compounds, compositions, and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

  Recently Added Patents
Bicycle carrier
Patient programmer with automated MRI compatibility verification for active implantable medical device
Method and apparatus for displaying system status with a wide range of viewing angle
Method for treating rheumatoid arthritis by administering an anti-IL-6 antibody and methotrexate
Sensor system
Inspection systems and methods for detecting defects on extreme ultraviolet mask blanks
Power converter with a variable reference voltage and inrush current limiting
  Randomly Featured Patents
Thin film transistor, method of manufacturing the same and flat panel display device having the same
Personal communication and positioning system
Monolithically integrated semiconductor unidirectional ring laser rotation sensor/gyroscope
Adjustable box wrench
Small building structure
Single hung self aligning door hinge
Method and installation for pumping an oil-well effluent
Signaling system for a telecommunications network
Heated cup holder system
Trailer hitch cycle rack