Resources Contact Us Home
Abuse-resistant amphetamine prodrugs

Image Number 11 for United States Patent #7662788.

The invention describes compounds, compositions, and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

  Recently Added Patents
Method of transmitting and receiving a paging message in a mobile communication system
Method and system of channel detecting and reporting, terminal, and management center
Non-serialized electronic product registration system and method of operating same
Anomalous data detection method
Lithographic apparatus and device manufacturing method
Antibodies to OX-2/CD200 and uses thereof
Information processing apparatus capable of authentication processing with improved user convenience, control program for information processing apparatus, and recording medium having control
  Randomly Featured Patents
High mass resolution magnet for ribbon beam ion implanters
Poly(arylene sulfide) resins reinforced with glass fibers
Adjustable vehicle seat suspension
Method for producing dual work function CMOS device
Configurable directional antenna
Microphone assembly
Tamper evident closure with push-pull pour spout
Self-adjusting hydraulic valve tappet
Linear ball bearing
Flap gate assembly