Resources Contact Us Home
S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer

Image Number 16 for United States Patent #7619000.

Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenicals has been considered a detoxification reaction. New organic arsenic derivatives have been synthesized, including S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid and S-dimethylarsino-thiobenzoic acid, and established its potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia. Results form a basis for the development of S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid, S-dimethylarsino-thiobenzoic acid, and other organic arsenicals as an anti-cancer therapy, combining high efficacy with very low, if any, toxicity.

  Recently Added Patents
Processing data using information embedded in a data request
Method for switching between virtualized and non-virtualized system operation
Method and apparatus for band switching in wireless local access network
Terminal for flat test probe
Transmitter having a programmable amplifier operating class
Disk drive
Energy storage device package
  Randomly Featured Patents
Water treatment device
LAN controller
Method for generating stroke-vector characters for use in a display system
Disk defibrator
Bed sheet having integrated sleeping pouch
Foamable polymeric composition comprising propylene polymer and hydrated alumina
Lupane triterpenoid derivatives
Device and method for optical control under diffuse illumination and observation means of crockery items or any glazed ceramic products
Generalized layer-2 VPNs
Aircraft engine thrust mount