Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer










Image Number 16 for United States Patent #7619000.

Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenicals has been considered a detoxification reaction. New organic arsenic derivatives have been synthesized, including S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid and S-dimethylarsino-thiobenzoic acid, and established its potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia. Results form a basis for the development of S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid, S-dimethylarsino-thiobenzoic acid, and other organic arsenicals as an anti-cancer therapy, combining high efficacy with very low, if any, toxicity.








 
 
  Recently Added Patents
Polyester resin for toner, electrostatic charge image developing toner, electrostatic charge image developer, toner cartridge, process cartridge, image forming apparatus, and image forming met
Cucumber plants with a compact growing habit
Method of controlling mechanical mechanisms of optical storage apparatus for peak power/current reduction, and related optical storage apparatus and machine-readable medium
Compatibility check
Coordinate measuring device and method for measuring with a coordinate measuring device
Method of using nutritional compounds dihydroquercetin (taxifolin) and arabinogalactan in combination with dihydroquercetin (taxifolin) to reduce and control cardiometabolic risk factors assoc
Sink
  Randomly Featured Patents
Method and apparatus for forming in-line core-filled pultruded profiles
Physical therapy exercise frame
Method and system for operating a near-to-eye display
Vehicle wheel alignment apparatus and method of use
Inhibitors of prenyl-protein transferase
Recovering non-volatile metals from dust containing metal oxides
Methods of providing antioxidants to a drug containing product
Collapsible chair
Rapid assay for testing overall oxidative stress
Semiconductor device having anti-reflective cap and spacer, method of manufacturing the same, and method of manufacturing photoresist pattern using the same