Resources Contact Us Home
S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer

Image Number 16 for United States Patent #7619000.

Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenicals has been considered a detoxification reaction. New organic arsenic derivatives have been synthesized, including S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid and S-dimethylarsino-thiobenzoic acid, and established its potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia. Results form a basis for the development of S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid, S-dimethylarsino-thiobenzoic acid, and other organic arsenicals as an anti-cancer therapy, combining high efficacy with very low, if any, toxicity.

  Recently Added Patents
Information processing apparatus, method for controlling information processing apparatus, and storage medium
Methods for forming patterned structures
Methods of diagnosing a plasmodium infection
Integrated touch screen
Milk frother
Systems and methods for tracking power modulation
Method for detecting security error in mobile telecommunications system and device of mobile telecommunications
  Randomly Featured Patents
Headgear securement system
Multispectral illumination device
Cap for a gas burner
Compositions and methods for bacterial immunity and secretion of proteins
Beam delivery apparatus
Method of removing alkyltetralins from an alkylbenzene mixture
Window slat
Xenon optical system for cinematograph projection