Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer










Image Number 16 for United States Patent #7619000.

Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenicals has been considered a detoxification reaction. New organic arsenic derivatives have been synthesized, including S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid and S-dimethylarsino-thiobenzoic acid, and established its potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia. Results form a basis for the development of S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid, S-dimethylarsino-thiobenzoic acid, and other organic arsenicals as an anti-cancer therapy, combining high efficacy with very low, if any, toxicity.








 
 
  Recently Added Patents
Press nut
Shot scent dispenser
Method and apparatus to select a profile of a digital communication line
Self-service administration of a database
Transmitting apparatus and retransmitting method
High voltage fast recovery trench diode
Converter and measuring apparatus
  Randomly Featured Patents
Image processing apparatus, image processing method and memory medium
Dual needle injection device
Immunoprophylactic polypeptides for schistosomiasis
Internal ATM-based multi-terminal client installation and method of operating same
Self aligning truck trailer
Photocatalyst sheet
Method of manufacturing resin boots for constant velocity universal joint
Cathode and lithium battery including the same
Inkjet head and inkjet printer
Option module, option program, printing system