Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer










Image Number 15 for United States Patent #7619000.

Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenicals has been considered a detoxification reaction. New organic arsenic derivatives have been synthesized, including S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid and S-dimethylarsino-thiobenzoic acid, and established its potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia. Results form a basis for the development of S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid, S-dimethylarsino-thiobenzoic acid, and other organic arsenicals as an anti-cancer therapy, combining high efficacy with very low, if any, toxicity.








 
 
  Recently Added Patents
Carbon dioxide capture system and methods of capturing carbon dioxide
Multi-state DC-DC converter having undirectional switches
Low temperature pressure chamber unit, magnetic resonance device with a low temperature pressure chamber unit, and an attachment method to attach at least one add-on unit to an external housin
Display device and projector
Detachably integrated battery charger for mobile cell phones and like devices
Storage system, control method therefor, and program
Drug delivery system
  Randomly Featured Patents
Tyrosine derivatives
Simultaneous bidirectional timing display
Pre-charging system for smoothing capacitor
20-HETE antagonists and agonists
Vertical centrifugal pump assembly
Sweeper
Hair-rinse liquid with pearly luster
Floor-mounted exercise machine
16-Dimethylaminomethylene-3-methoxy-1,3,5-(10)-estratrien-17-one, a process for the preparation thereof and its use as a preparative intermediate
Rigid PCMCIA frame kit