Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer










Image Number 15 for United States Patent #7619000.

Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenicals has been considered a detoxification reaction. New organic arsenic derivatives have been synthesized, including S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid and S-dimethylarsino-thiobenzoic acid, and established its potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia. Results form a basis for the development of S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid, S-dimethylarsino-thiobenzoic acid, and other organic arsenicals as an anti-cancer therapy, combining high efficacy with very low, if any, toxicity.








 
 
  Recently Added Patents
Glove
Food-grade flour from dry fractionated corn germ and collet composition and method for producing same
Light fixture
Liposomes with improved drug retention for treatment of cancer
Server-side connection resource pooling
LED package chip classification system
Rules-based approach to transferring and/or viewing medical images
  Randomly Featured Patents
Embrittlement machining method
Apparatus for positioning a component of an exercise device
Method for producing a liquid crystal polyester resin composition having plating strength
Integrated circuit package with permanent identification of device characteristics and method for adding the same
Waterproof mobile device camera case
Programmable logic array having local and long distance conductors
Signal transmitting device and signal receiving device
Snack food container cap
Novel sulfonyl imide intermediates
BOAS with micro serpentine cooling