Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer










Image Number 15 for United States Patent #7619000.

Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenicals has been considered a detoxification reaction. New organic arsenic derivatives have been synthesized, including S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid and S-dimethylarsino-thiobenzoic acid, and established its potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia. Results form a basis for the development of S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid, S-dimethylarsino-thiobenzoic acid, and other organic arsenicals as an anti-cancer therapy, combining high efficacy with very low, if any, toxicity.








 
 
  Recently Added Patents
Passive charge cord release system for an electric vehicle
Sublingual coated tablet of fentanyl
Glow in the dark swim goggle frame and band
Method and device for detecting the dysfunction of a gas pressure sensor in a vehicle tire
System and methods for facilitating and documenting user thinking and learning using enhanced interactive constructs
Communication device
Communication apparatus, power supply control method, display apparatus, communication method, and computer program product
  Randomly Featured Patents
Electro-acoustic transducer with variable thickness foam surfaced diaphragm
Paper organizer
Beam characterization monitor for sensing pointing or angle of an optical beam
Small animal trap with infrared trigger
Read circuit for non-volatile memories
Dye composition for keratin fibers, with a cationic direct dye and a substantive polymer
Magnetoresistive head
Gangway for a railway car passageway
SRAM system having very lightly doped SRAM load transistors for improving SRAM cell stability and method for making the same
Methods for functional kidney imaging using small dendrimer contrast agents