Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer










Image Number 15 for United States Patent #7619000.

Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenicals has been considered a detoxification reaction. New organic arsenic derivatives have been synthesized, including S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid and S-dimethylarsino-thiobenzoic acid, and established its potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia. Results form a basis for the development of S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid, S-dimethylarsino-thiobenzoic acid, and other organic arsenicals as an anti-cancer therapy, combining high efficacy with very low, if any, toxicity.








 
 
  Recently Added Patents
Catalyst, production process therefor and use thereof
Bearing assemblies, and bearing apparatuses and motor assemblies using same
Shower caddy
Tunable wireless energy transfer systems
Multi-level supply chain management system and methods
System and method for intent data processing
Device and partial mold for the production of rotor blades for wind power plants and methods for the production
  Randomly Featured Patents
Method for producing a low fat meat product
Thin film transistor substrate having structure for compensating for mask misalignment
System for monitoring and control of the circulation lubrication of the bearings of cylinders and rolls in a paper machine
System and method for radio signal reconstruction using signal processor
Cooling roll for producing quenched thin metal tape
Ball screw
Peak detector with feedback
Fuel reformer catalyst and absorbent materials
Video interface and overlay system and process
Even-order harmonic cancellation and increased RF gain using dual-output mach-zehnder modulator with two wavelength input