Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer










Image Number 15 for United States Patent #7619000.

Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenicals has been considered a detoxification reaction. New organic arsenic derivatives have been synthesized, including S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid and S-dimethylarsino-thiobenzoic acid, and established its potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia. Results form a basis for the development of S-dimethylarsino-glutathione, S-dimethylarsino-thiosuccinic acid, S-dimethylarsino-thiobenzoic acid, and other organic arsenicals as an anti-cancer therapy, combining high efficacy with very low, if any, toxicity.








 
 
  Recently Added Patents
Detecting the type of NAT firewall using messages
Compact ion accelerator source
Method for using extended security system, extended security system and devices
Radiation-curable ink composition, ink jet recording method, and recorded matter
Shipping container explosives and contraband detection system using nuclear quadrupole resonance
Trading related to fund compositions
Method of monitoring and configuring
  Randomly Featured Patents
Precision solder resist registration inspection method
Shower control valve
Device containing non-blinking quantum dots
Seat belt shield with attaching clips
Semiconductor circuit
Display device for copying machines and the like
Woven intravascular devices and methods for making the same and apparatus for delivery of the same
Developer containing device, image forming apparatus, and image forming system with housing sections welded together by vibration welding
SRAM constructions, and electronic systems comprising SRAM constructions
Embedded wear sensor