Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Methods of therapy for B-cell malignancies using antagonist anti-CD40 antibodies










Image Number 6 for United States Patent #7611708.

Methods of therapy for B-cell malignancies are provided. The methods comprise administering a therapeutically effective amount of an antagonist anti-CD40 antibody or antigen-binding fragment thereof to a patient in need thereof. The antagonist anti-CD40 antibody or antigen-binding fragment thereof is free of significant agonist activity when the antibody binds a CD40 antigen on a normal human B cell, exhibits antagonist activity when the antibody binds a CD40 antigen on a malignant human B cell, and can exhibit antagonist activity when the antibody binds a CD40 antigen on a normal human B cell. Antagonist activity of the anti-CD40 antibody or antigen-binding fragment thereof beneficially inhibits proliferation and/or differentiation of malignant human B cells.








 
 
  Recently Added Patents
Data center management unit with improved disaster prevention and recovery
Method for conformal plasma immersed ion implantation assisted by atomic layer deposition
Method and apparatus for monitoring wireless communication in hearing assistance systems
Battery loading and unloading mechanism
Electrode composition with enhanced performance characteristics
Biomarkers of gastric cancer and use thereof
Developing device
  Randomly Featured Patents
Data conversion system for line-narrowing a pattern
Flexible photosensitive polymer composition with azide and/or amine compound, poly(amic acid) and highly polar compound with boiling point above 150.degree. C.
Open quadrature whole volume imaging NMR surface coil array including three figure-8 shaped surface coils
Sports harness for a portable radio/cassette player
Portable telephone or similar article
Image recognition system and recognition method thereof, and program
Combined adjustable desk lamp and detachable desk organizer
Encoder apparatus and methods
Radio location system for precisely tracking objects by RF transceiver tags which randomly and repetitively emit wideband identification signals
Portable communication device