Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Methods of therapy for B-cell malignancies using antagonist anti-CD40 antibodies










Image Number 6 for United States Patent #7611708.

Methods of therapy for B-cell malignancies are provided. The methods comprise administering a therapeutically effective amount of an antagonist anti-CD40 antibody or antigen-binding fragment thereof to a patient in need thereof. The antagonist anti-CD40 antibody or antigen-binding fragment thereof is free of significant agonist activity when the antibody binds a CD40 antigen on a normal human B cell, exhibits antagonist activity when the antibody binds a CD40 antigen on a malignant human B cell, and can exhibit antagonist activity when the antibody binds a CD40 antigen on a normal human B cell. Antagonist activity of the anti-CD40 antibody or antigen-binding fragment thereof beneficially inhibits proliferation and/or differentiation of malignant human B cells.








 
 
  Recently Added Patents
Image forming apparatus and method of translating virtual memory address into physical memory address
Face recognition through face building from two or more partial face images from the same face
Methods for processing 2Nx2N block with N being positive integer greater than four under intra-prediction mode and related processing circuits thereof
Efficient forward ranking in a search engine
Proximity sensor arrangement in a mobile device
Nacelle cover
Stackable clothes drying apparatus
  Randomly Featured Patents
Substituted 4-hetaryl-pyrazolines as pest control agents
Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
Ring binder
Reversible glove
Traveling trench shore
Deployable sensor module
Blood pressure measuring device
Ground fault interrupter wiring device with improved latching and actuating components
Method and apparatus for serial dot printing
Kiosk for the assessment of behavioral and neurological disorders