Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Methods of therapy for B-cell malignancies using antagonist anti-CD40 antibodies










Image Number 6 for United States Patent #7611708.

Methods of therapy for B-cell malignancies are provided. The methods comprise administering a therapeutically effective amount of an antagonist anti-CD40 antibody or antigen-binding fragment thereof to a patient in need thereof. The antagonist anti-CD40 antibody or antigen-binding fragment thereof is free of significant agonist activity when the antibody binds a CD40 antigen on a normal human B cell, exhibits antagonist activity when the antibody binds a CD40 antigen on a malignant human B cell, and can exhibit antagonist activity when the antibody binds a CD40 antigen on a normal human B cell. Antagonist activity of the anti-CD40 antibody or antigen-binding fragment thereof beneficially inhibits proliferation and/or differentiation of malignant human B cells.








 
 
  Recently Added Patents
Processor engine, integrated circuit and method therefor
Tranverse in-core probe monitoring and calibration device for nuclear power plants, and method thereof
Image forming system, printing control method, and program
Luminaire
Multilayered ceramic electronic component and fabrication method thereof
System and method for backup communication over ethernet
Pressure-sensitive adhesive composition for optical films, pressure-sensitive adhesive optical film and image display
  Randomly Featured Patents
Method of manufacturing a liquid ejecting head
Method of conferring immuno-tolerance to a specific antigen
Cytokine-induced marker for inflammatory response
Enhanced power distribution in an integrated circuit
Process for refining metal
Heterobicyclic sulfonamide and sulfonic ester derivatives
Pulsed light source spectrometer with interferometer
Gel structure for combined EMI shielding and thermal control of microelectronic assemblies
Cast ingot position control process and apparatus
Engine control system with mixed exhaust gas oxygen sensor types