Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Methods of therapy for B-cell malignancies using antagonist anti-CD40 antibodies










Image Number 6 for United States Patent #7611708.

Methods of therapy for B-cell malignancies are provided. The methods comprise administering a therapeutically effective amount of an antagonist anti-CD40 antibody or antigen-binding fragment thereof to a patient in need thereof. The antagonist anti-CD40 antibody or antigen-binding fragment thereof is free of significant agonist activity when the antibody binds a CD40 antigen on a normal human B cell, exhibits antagonist activity when the antibody binds a CD40 antigen on a malignant human B cell, and can exhibit antagonist activity when the antibody binds a CD40 antigen on a normal human B cell. Antagonist activity of the anti-CD40 antibody or antigen-binding fragment thereof beneficially inhibits proliferation and/or differentiation of malignant human B cells.








 
 
  Recently Added Patents
Method of bonding metallic members, and metallic bonded body
Systems and methods to provide report part via a web service
Grounding fitting
Metal melting apparatus and method for melting metal
Shower bench
Engine RPM control device
Access control method, information display device using the same, and information display system
  Randomly Featured Patents
Bottle with integrated grip portion
Frictionally engaged adjustable wire basket
Rehabilitation apparatus and method
Front illuminating device and a reflection-type liquid crystal display using such a device
Retractable surgical safety knife
Polynucleotides encoding C-type lectin polypeptides and methods of use thereof
Manufacture of complex hydrides
Soap holder
Integrated having a self-aligned Cu diffusion barrier
Derivatives of 2,5-dihydroxyphenylcarboxylic acids, and their utilization in cosmetic or dermatological compositions with a depigmenting action