Resources Contact Us Home
Pan-HER antagonists and methods of use

Image Number 7 for United States Patent #7557181.

The present invention features human epidermal receptor (HER) antagonists. These antagonists are polypeptide variants of ligands of HER. The HER ligand polypeptide variants of the invention possess Pan-HER antagonistic properties and can inhibit at least one HER-mediated biological activity of one or more HER subtypes, such as inhibition of the receptor's kinase activation activity and subsequently, cell proliferation. Such polypeptide variants, and nucleic acids encoding these polypeptide variants can be used therapeutically in situations in which inhibition of HER activity is indicated.

  Recently Added Patents
Modular CID assembly for a lithium ion battery
Constant temperature light emitting diode lighting system
Image signal processing apparatus, image signal processing method, recording medium, and integrated circuit
Backlight module
Scan test circuitry with delay defect bypass functionality
Telephone switching systems
Golf ball with adjustable tackiness
  Randomly Featured Patents
Dynamic memory placement policies for NUMA architecture
Structure for expanding the capacity of luggage
Reflective liquid crystal modulator based printing system
Chrondroitin sulfate/sodium hyaluronate composition
Thermally reflective encapsulated phase change pigment
Molten carbonate fuel cell
Electrical connector with high intensity contacts
Sachet formulations
Liquid ejecting head and liquid ejecting apparatus
Polyamide-ester from polyethylene glycol monoamine and catalytic process therefor