Resources Contact Us Home
Pan-HER antagonists and methods of use

Image Number 7 for United States Patent #7557181.

The present invention features human epidermal receptor (HER) antagonists. These antagonists are polypeptide variants of ligands of HER. The HER ligand polypeptide variants of the invention possess Pan-HER antagonistic properties and can inhibit at least one HER-mediated biological activity of one or more HER subtypes, such as inhibition of the receptor's kinase activation activity and subsequently, cell proliferation. Such polypeptide variants, and nucleic acids encoding these polypeptide variants can be used therapeutically in situations in which inhibition of HER activity is indicated.

  Recently Added Patents
Semiconductor device and manufacturing method thereof
Method and system for dynamic digital rights bundling
Inter-cell power control in the presence of fractional frequency reuse
Lubricant coating device and image forming apparatus
Light-emitting element, light-emitting device, and electronic device
FET device having ultra-low on-resistance and low gate charge
Image stabilization apparatus and image pickup apparatus
  Randomly Featured Patents
Image squeezing circuit for squeezing ordinary-sized image into smaller area
Integrated service tower
Gasoline sulfur reduction in fluid catalytic cracking
3-Halo cephalosporins
Aluminum trade gun
Method for the sub-critical drying of lyogels to produce aerogels
Focusing color LED emitter
Delivery system for meristematic tissue
Bituminous composition
Metal wood club with improved hitting face