Resources Contact Us Home
Compositions and methods for non-targeted activation of endogenous genes

Image Number 14 for United States Patent #7419828.

The present invention is directed generally to activating gene expression or causing over-expression of a gene by recombination methods in situ. The invention also is directed generally to methods for expressing an endogenous gene in a cell at levels higher than those normally found in the cell. In one embodiment of the invention, expression of an endogenous gene is activated or increased following integration into the cell, by non-homologous or illegitimate recombination, of a regulatory sequence that activates expression of the gene. The invention also provides methods for the identification, activation, isolation, and/or expression of genes undiscoverable by current methods since no target sequence is necessary for integration. The invention is specifically directed to methods of drug discovery using the activated gene products for compound testing.

  Recently Added Patents
Display screen or portion thereof with graphical user interface
Heating pad
LED package with top and bottom electrodes
Antenna device and wireless communication apparatus
Correction information calculating device, image processing apparatus, image display system, and image correcting method
UV liquid treatment system
String changing tool with a quick connector assembly and worm gear string cutter
  Randomly Featured Patents
Charger device
Ring oscillator circuit
Method, network system and center for intermediating transactions
Bumped semiconductor device having a trench for stress relief
Pump shaft bearing protection system
Tool to install elbow joint and clamp
Flame retardant resin composition
Dual spring valve stem seal module
Tangent function generator for AM stereo
Portable device for the measurement and control of analytes in biological fluids