Resources Contact Us Home
Compositions and methods for non-targeted activation of endogenous genes

Image Number 14 for United States Patent #7419828.

The present invention is directed generally to activating gene expression or causing over-expression of a gene by recombination methods in situ. The invention also is directed generally to methods for expressing an endogenous gene in a cell at levels higher than those normally found in the cell. In one embodiment of the invention, expression of an endogenous gene is activated or increased following integration into the cell, by non-homologous or illegitimate recombination, of a regulatory sequence that activates expression of the gene. The invention also provides methods for the identification, activation, isolation, and/or expression of genes undiscoverable by current methods since no target sequence is necessary for integration. The invention is specifically directed to methods of drug discovery using the activated gene products for compound testing.

  Recently Added Patents
Generating a network map
Wireless control system for a patient support apparatus
Metal colloidal particles, metal colloid and use of metal colloid
Print processing method, print relay server, control method, and storage medium to reserve print data
Evolutionary clustering algorithm
Face recognition through face building from two or more partial face images from the same face
Image sensing apparatus and method of controlling the image sensing apparatus
  Randomly Featured Patents
Furnace for heating pipes with upset portions
Humidifier, vaporizer and room freshener
Universal controller expansion module system, method and apparatus
Protein product
Hybrid analog and digital architecture for controlling backlight light emitting diodes of an electronic display
Semiconductor device and manufacturing method of semiconductor device
Boot system and method having a BIOS that reads an operating system from first storage device via an input/output chip based on detecting a temperature of a second storage device
Bottle with closure element for receiving syringe and method therefor
Advanced chemical mechanical polishing system with smart endpoint detection