Resources Contact Us Home
Compositions and methods for non-targeted activation of endogenous genes

Image Number 14 for United States Patent #7419828.

The present invention is directed generally to activating gene expression or causing over-expression of a gene by recombination methods in situ. The invention also is directed generally to methods for expressing an endogenous gene in a cell at levels higher than those normally found in the cell. In one embodiment of the invention, expression of an endogenous gene is activated or increased following integration into the cell, by non-homologous or illegitimate recombination, of a regulatory sequence that activates expression of the gene. The invention also provides methods for the identification, activation, isolation, and/or expression of genes undiscoverable by current methods since no target sequence is necessary for integration. The invention is specifically directed to methods of drug discovery using the activated gene products for compound testing.

  Recently Added Patents
Vehicle and method for controlling vehicle
Method and system for acquiring support capability of mobile terminal by base station side system
Pattern forming method using developer containing organic solvent and rinsing solution for use in the pattern forming method
Light powered hearing aid
Providing a web page to a client
Generating and using checkpoints in a virtual computer system
  Randomly Featured Patents
Coil bobbin for motor
Faucet handle
Automatic mobile device detection
Process for preparing .DELTA..sup.22 -25-oxy substituted sterol derivatives
Solid phase parallel synthesis of tertiary amines
Pin driver
Tire tread
Variable water flow and dilution chemical dispenser
Programmable semiconductor memory
C.sub.3 to C.sub.5 polyfluoroalkanes propellants