Resources Contact Us Home
Compositions and methods for non-targeted activation of endogenous genes

Image Number 14 for United States Patent #7419828.

The present invention is directed generally to activating gene expression or causing over-expression of a gene by recombination methods in situ. The invention also is directed generally to methods for expressing an endogenous gene in a cell at levels higher than those normally found in the cell. In one embodiment of the invention, expression of an endogenous gene is activated or increased following integration into the cell, by non-homologous or illegitimate recombination, of a regulatory sequence that activates expression of the gene. The invention also provides methods for the identification, activation, isolation, and/or expression of genes undiscoverable by current methods since no target sequence is necessary for integration. The invention is specifically directed to methods of drug discovery using the activated gene products for compound testing.

  Recently Added Patents
Image forming apparatus forming images in response to image formation request from operation unit or external device
Front exterior of an automotive tail lamp
Multi-level integrated circuit, device and method for modeling multi-level integrated circuits
Method and apparatus for policy-based network access control with arbitrary network access control frameworks
Methods and arrangements for realising betting with off-line terminal
Method and system for simulating wireless networks
Dihydronaphthyridinyl(organo)methanone analogs as positive allosteric mGluR5 modulators
  Randomly Featured Patents
Vehicle with movable and inwardly tilting safety body
Character processing method
Self compensating ducted rocket motor fuel nozzle and method for regulating fuel generation
Door-mounted gasket for comb-type rear frame
Increasing the read signal in ferroelectric memories
Circuit for normalizing devices having current-controlled frequency response to predetermined I-F characteristic
Method and apparatus for performing head-tail discrimination of electronic chip components
Speed reducer for use in yaw drive apparatus for wind power generation apparatus, and yaw drive method and apparatus for wind power generation apparatus using the speed reducer
Light display system
Apparatus and method for controlling the magnitude spectrum of acoustically combined signals