Resources Contact Us Home
Antisense oligonucleotides targeted to human CDC45

Image Number 4 for United States Patent #7393950.

Antisense oligonucleotides that inhibit expression of human replication-initiation protein as well as methods of preventing or treating hyperproliferative conditions using said oligonucleotides are disclosed. One aspect provides an antisense oligonucleotides that inhibits the expression of human replication-initiation protein and has a sequence complementary to at least a portion of a target sequence encoding a human replication-initiation gene. By administering a therapeutically effective amount of antisense oligonucleotides or by contacting the hyperproliferating cells with an effective amount of antisense oligonucleotides, expression of replication-initiation protein is inhibited. Methods of screening and testing active antisense oligonucleotides for their ability to inhibit gene expression are also disclosed.

  Recently Added Patents
Concentration measuring apparatus for hydrogen sulfide in gas flow, and method for determining sulfide ion
Dual functional medium shredding machine structure
Heat shield and laminated glass
Method for media access controlling and system and method for channel time reservation in distributed wireless personal area network
Bi-directional, compact, multi-path and free space channel replicator
Pharmaceutical dosage form
  Randomly Featured Patents
Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
Electronic device and method for manufacturing the same
Selective deposition modeling method and apparatus for forming three-dimensional objects and supports
Apparatus and method of loading lens-fitted photo film unit with photo film
Toy motorcycle and launcher apparatus
Apparatus for taking out and aligning articles transported thereto
Generating device of phase current instruction value for alternating current servomotor and the generating method thereof
Grounded electrode for a plasma processing apparatus
Gate driving device and flat display device employing such a gate driving device
System for the automatic testing, preferably on a bench, of electronic control systems which are intended to be fitted in vehicles