Resources Contact Us Home
Antisense oligonucleotides targeted to human CDC45

Image Number 4 for United States Patent #7393950.

Antisense oligonucleotides that inhibit expression of human replication-initiation protein as well as methods of preventing or treating hyperproliferative conditions using said oligonucleotides are disclosed. One aspect provides an antisense oligonucleotides that inhibits the expression of human replication-initiation protein and has a sequence complementary to at least a portion of a target sequence encoding a human replication-initiation gene. By administering a therapeutically effective amount of antisense oligonucleotides or by contacting the hyperproliferating cells with an effective amount of antisense oligonucleotides, expression of replication-initiation protein is inhibited. Methods of screening and testing active antisense oligonucleotides for their ability to inhibit gene expression are also disclosed.

  Recently Added Patents
System and method for browsing tabbed-heterogeneous windows
Method and apparatus for verifiable generation of public keys
Zoom lens
High throughput thin film characterization and defect detection
Antimicrobial flush solutions
Quantifying the risks of applications for mobile devices
Method and system for parallelizing data copy in a distributed file system
  Randomly Featured Patents
Process for the production of polyphenylene-oxide
Leaf bag and collapsible frame
Distributed processing system for performing memory assignment
Prevulcanization retardation of free-radical cured rubber
Wall mounting device for electronic equipment case
Propylene copolymers for adhesive applications
Machine tool with automatic tool changer
Compositions containing mold release agents
Swim training apparatus
Wire shipping and dispensing package