Resources Contact Us Home
Antisense oligonucleotides targeted to human CDC45

Image Number 4 for United States Patent #7393950.

Antisense oligonucleotides that inhibit expression of human replication-initiation protein as well as methods of preventing or treating hyperproliferative conditions using said oligonucleotides are disclosed. One aspect provides an antisense oligonucleotides that inhibits the expression of human replication-initiation protein and has a sequence complementary to at least a portion of a target sequence encoding a human replication-initiation gene. By administering a therapeutically effective amount of antisense oligonucleotides or by contacting the hyperproliferating cells with an effective amount of antisense oligonucleotides, expression of replication-initiation protein is inhibited. Methods of screening and testing active antisense oligonucleotides for their ability to inhibit gene expression are also disclosed.

  Recently Added Patents
Stacked structure and stacked method for three-dimensional chip
Approaching object detection system
Integrated process for the manufacture of fluorinated olefins
Methods and apparatus for low power out-of-band communications
Sending notification of event
Reading apparatus and reading method
Optical scanner and image-forming device
  Randomly Featured Patents
Transportable medical apparatus, in particular infusion supply apparatus
Utility trailer with level load support to and from the ground
Dynamically configurable IP based wireless device and wireless networks
Cornering identification method
Arborist's climbing rope
Sealed rechargeable battery
Substate-treating device
Transition metal complexes with bidentate ligand having an imidazole ring
Self-locking, universal trailer hitch and method of use thereof