Resources Contact Us Home
Short amphipathic peptides with activity against bacteria and intracellular pathogens

Image Number 3 for United States Patent #7262163.

"Minimalist" antimicrobial peptides are disclosed based on 50 to 80% .alpha.,.alpha.-dialkylated amino acids. The peptides are short, cationic, amphipathic, and possess a high helix propensity. Polar .alpha.,.alpha.-dialkylated amino acids are also disclosed. These peptides are easy and inexpensive to synthesize via solid-phase techniques. The peptides exhibit in vitro anti-bacterial properties at concentrations that are not lethal to normal mammalian cells. The peptides exhibit in vivo bioactivity against intracellular pathogens.

  Recently Added Patents
Data distribution unit for vehicle entertainment system
Magnetic detection of small entities
Image forming unit having agitating portion and image forming apparatus
Pre-fetching map data using variable map tile radius
Image generation based on a plurality of overlapped swathes
Double diffused metal oxide semiconductor device and manufacturing method thereof
  Randomly Featured Patents
Digital image processing using face detection information
Scribe guide
Load cell interface for a bed having a stud receiver with a roller axis parallel with an axis of a load cell stud
Method and apparatus for monitoring a movable barrier over a network
Diols by transesterification using magnesia catalysts
Connector with a terminal protecting board
Truck operated transfer system apparatus and method
Output circuit and semiconductor integrated circuit device
Aorto femoral bifurcation graft and method of implantation
Method for recombinant fibrinogen production