Resources Contact Us Home
Short amphipathic peptides with activity against bacteria and intracellular pathogens

Image Number 3 for United States Patent #7262163.

"Minimalist" antimicrobial peptides are disclosed based on 50 to 80% .alpha.,.alpha.-dialkylated amino acids. The peptides are short, cationic, amphipathic, and possess a high helix propensity. Polar .alpha.,.alpha.-dialkylated amino acids are also disclosed. These peptides are easy and inexpensive to synthesize via solid-phase techniques. The peptides exhibit in vitro anti-bacterial properties at concentrations that are not lethal to normal mammalian cells. The peptides exhibit in vivo bioactivity against intracellular pathogens.

  Recently Added Patents
Computerized on-board system for controlling a train
Device, system, and method for logging near field communications tag interactions
Methods and systems for creating a tail risk hedge index and trading derivative products based thereon
Evaluating programmer efficiency in maintaining software systems
Using location based services for determining a calling window
Managing aging of silicon in an integrated circuit device
Event-triggered server-side macros
  Randomly Featured Patents
Surface-emitting light-emitting diode
Key recovery mechanism for cryptographic systems
Method and apparatus for dynamically reprogramming remote autonomous agents
Carotenoid composition
Transportable refrigerant transfer unit and methods of using the same
Junction for medical instruments
Close pitch harnessing device
Method of controlling current of high-speed switched reluctance motor
Abrasion resistant roller apparatus for internal combustion engines