Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Short amphipathic peptides with activity against bacteria and intracellular pathogens










Image Number 3 for United States Patent #7262163.

"Minimalist" antimicrobial peptides are disclosed based on 50 to 80% .alpha.,.alpha.-dialkylated amino acids. The peptides are short, cationic, amphipathic, and possess a high helix propensity. Polar .alpha.,.alpha.-dialkylated amino acids are also disclosed. These peptides are easy and inexpensive to synthesize via solid-phase techniques. The peptides exhibit in vitro anti-bacterial properties at concentrations that are not lethal to normal mammalian cells. The peptides exhibit in vivo bioactivity against intracellular pathogens.








 
 
  Recently Added Patents
Vacuum cleaner
Nanocatalysts structure, process for the preparation and use thereof
.beta.-2 microglobulin as a biomarker for peripheral artery disease
Mobile browser context switching
Battery pouch sheet edge insulation
Sink
Web-based system and method for video analysis
  Randomly Featured Patents
Fire suppression systems
Methods for treating microbial infections
Valved fenestrated tracheotomy tube having outer and inner cannulae
Double-conversion television tuner using a Delta-Sigma Fractional-N PLL
Method of controlling transmission power in a cellular type mobile communication system
Adaptive control of cutting machining operations
Method for forming a memory device by utilizing variations in resistance value
Phase locked signal generator
Room temperature chemical trap for the purification of gaseous methane
Client security for networked applications