Resources Contact Us Home
Short amphipathic peptides with activity against bacteria and intracellular pathogens

Image Number 3 for United States Patent #7262163.

"Minimalist" antimicrobial peptides are disclosed based on 50 to 80% .alpha.,.alpha.-dialkylated amino acids. The peptides are short, cationic, amphipathic, and possess a high helix propensity. Polar .alpha.,.alpha.-dialkylated amino acids are also disclosed. These peptides are easy and inexpensive to synthesize via solid-phase techniques. The peptides exhibit in vitro anti-bacterial properties at concentrations that are not lethal to normal mammalian cells. The peptides exhibit in vivo bioactivity against intracellular pathogens.

  Recently Added Patents
Anti-infective agents and uses thereof
Fluid-borne particle detector
Wide bandwidth hybrid antenna for combination EAS and RFID label or tag
Method of making a CIG target by cold spraying
Imaging device, method and computer readable medium
Maintenance guidance display device, maintenance guidance display method, and maintenance guidance display program
Cross-platform cloud-based map creation
  Randomly Featured Patents
Sex pheromone synergist
Process for the production of dicalcium phosphate
Way to remove Cu line damage after Cu CMP
Configuration and control unit for a heterogeneous multi-system
Establishing eye contact in video conferencing
Silicon micro machined occlusion implant
Automatic voltage regulation for processors having different voltage requirements and unified or split voltage planes
Air conditioning system of heat pump type
Polymer dye and method for producing the same and its use in light-emitting diodes and other optical components
Evaporative carburetor and engine