Resources Contact Us Home
Short amphipathic peptides with activity against bacteria and intracellular pathogens

Image Number 3 for United States Patent #7262163.

"Minimalist" antimicrobial peptides are disclosed based on 50 to 80% .alpha.,.alpha.-dialkylated amino acids. The peptides are short, cationic, amphipathic, and possess a high helix propensity. Polar .alpha.,.alpha.-dialkylated amino acids are also disclosed. These peptides are easy and inexpensive to synthesize via solid-phase techniques. The peptides exhibit in vitro anti-bacterial properties at concentrations that are not lethal to normal mammalian cells. The peptides exhibit in vivo bioactivity against intracellular pathogens.

  Recently Added Patents
Simplified algorithm for abnormal situation prevention in load following applications including plugged line diagnostics in a dynamic process
Light emitting device
Organic light emitting display apparatus
Titanium compounds and complexes as additives in lubricants
Display window with level of service graphical user interface
Method and system for providing geohazard information to customers
Purine compounds used as CB2 agonists
  Randomly Featured Patents
Convertible top for a vehicle having a rear egress
Coiling device for cordage material
Microemulsion or in-situ microemulsion for releasing stuck pipe
Detector device responsive to infrared radiation
Flexible linkage system for environmentally sealed parachutes and other safety devices
Continuous feed forms for demand printers
Process for methane conversion
Method of making random array of microspheres using enzyme digestion
Illuminated ceiling fan
Stackable drawer system