Resources Contact Us Home
Short amphipathic peptides with activity against bacteria and intracellular pathogens

Image Number 3 for United States Patent #7262163.

"Minimalist" antimicrobial peptides are disclosed based on 50 to 80% .alpha.,.alpha.-dialkylated amino acids. The peptides are short, cationic, amphipathic, and possess a high helix propensity. Polar .alpha.,.alpha.-dialkylated amino acids are also disclosed. These peptides are easy and inexpensive to synthesize via solid-phase techniques. The peptides exhibit in vitro anti-bacterial properties at concentrations that are not lethal to normal mammalian cells. The peptides exhibit in vivo bioactivity against intracellular pathogens.

  Recently Added Patents
Apparatus for touch screen avionic device
Pluggable power cell for an inverter
Portion of display panel or screen with an icon
ActRIIB proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy
Mobile device case with storage compartment
Protocol delay measuring device and protocol delay measuring method
Color stable manganese-doped phosphors
  Randomly Featured Patents
Non-oscillating socket joint
Method for producing vitamin B12 from hydrogen-metabolizing methane bacterium
Methods and systems for limiting mobile station operation in a group setting
Depleted poly mosfet structure and method
Method and apparatus for optically determining note characteristics from key motion in a keyboard operated musical instrument
New Guinea Impatiens plant named `Duepetpich`
Borosilicate glass of greater resistance to chemical attack and applications thereof
Automated low-volume tangential flow filtration process development device
Magnetic bladder cycler
Continuously adjustable rotary bias device