Resources Contact Us Home
Modified factor VIII

Image Number 8 for United States Patent #7012132.

Specific amino acid loci of human factor VIII interact with inhibitory antibodies of hemophilia patients who have developed such antibodies after being treated with factor VIII. Modified factor VIII is disclosed in which the amino acid sequence is changed by a substitution at one or more of the specific loci. The modified factor VIII is not inhibited by inhibitory antibodies against the A2 or C2 domain epitopes. The modified factor VIII is useful for hemophiliacs, either to avoid or prevent the action of inhibitory antibodies.

  Recently Added Patents
Electronic device with multi-orientation
Maesa japonica extracts and methods of use
Error recovery storage along a memory string
Credit flow control scheme in a router with flexible link widths utilizing minimal storage
Controller with screen
Phone messaging using audio streams
Printing apparatus having extendable functionality and method thereof
  Randomly Featured Patents
Method and apparatus for handling reordered data packets
Video editing apparatus
Resin intake manifolds and manufacturing process thereof
Method and apparatus for increasing the operating frequency of an electronic circuit
Serving advertisements based on content
Split energy level radiation detection
Image heating apparatus
Process for production of 2-acetylbenzo[b]thiophene
Group supervisory system of elevator cars
Fast-lowering hydraulic equipment