Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Modified factor VIII










Image Number 5 for United States Patent #7012132.

Specific amino acid loci of human factor VIII interact with inhibitory antibodies of hemophilia patients who have developed such antibodies after being treated with factor VIII. Modified factor VIII is disclosed in which the amino acid sequence is changed by a substitution at one or more of the specific loci. The modified factor VIII is not inhibited by inhibitory antibodies against the A2 or C2 domain epitopes. The modified factor VIII is useful for hemophiliacs, either to avoid or prevent the action of inhibitory antibodies.








 
 
  Recently Added Patents
Nickel-cobalt-manganese multi-element lithium ion battery cathode material with dopants and its methods of preparation
Parameter decoding apparatus and parameter decoding method
Method and apparatus for optimizing paging in a communication network
Reserving a time block in a calendar application to account for a travel time between geographic locations of appointments
Method and system for fail-safe call survival
Knife grip
Server chassis
  Randomly Featured Patents
Saw guide for annularly corrugated cables
System and method for dynamically and efficently directing evacuation of a building during an emergency condition
Control of a brushless motor
Distributed text-to-speech synthesis between a telephone network and a telephone subscriber unit
Remote control for electric blanket
Methods and tools for femoral resection in primary knee surgery
Gas generator
Fuel assembly for a nuclear reactor
Electronic circuit breaker
Thermal latent image material and method of producing and developing the same