Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Method for prediction of bone fractures by osteocalcin measurements










Image Number 2 for United States Patent #6967081.

This invention concerns a method for the assessment of bone fragility and fracture risk, or osteoporosis, in a person. In said method, the concentration of gamma-carboxylated osteocalcin (COC) and optionally also the concentration of intact or total osteocalcin (IOC or TOC, respectively) in a body fluid sample of said person is measured. The concentration of gamma-carboxylated osteocalcin (COC) so obtained is compared to the mean concentration of gamma-carboxylated osteocalcin (mean COC) in similar body fluid samples of the population of the same age and sex. Alternatively, the determined ratio COC/IOC or COC/TOC for said person, is compared to the mean ratio COC/IOC or COC/TOC, (mean ratio COC/IOC or mean ratio COC/TOC) determined from measurements in similar body fluid samples of the population of the same age and sex. A measured COC that is lower than the mean COC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. Preferably, a determined ratio COC/TOC that is lower than the mean ratio COC/TOC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. The invention concerns further kits for use in the assessment according to this invention.








 
 
  Recently Added Patents
Stool
Editing device and editing method
Semiconductor device
Wireless communications system, wireless communications apparatus, wireless communications method and computer program for wireless communication
High-accuracy centered fractional fourier transform matrix for optical imaging and other applications
Inhibitors of bacterial tyrosine kinase and uses thereof
Apparatus and method for adapted deblocking filtering strength
  Randomly Featured Patents
Flexible sheet molding compound and method of making the same
Volatile actives dispenser
Patient support cart
Rotate/rotate method and apparatus for computed tomography x-ray inspection of large objects
Method for manufacturing a capacitor lower electrode over a transistor and a bit line corresponding to a cell area of a semiconductor device
Separator for separating out particles of fatty substances from a gas current, more specifically from waste air from kitchens, and a waste air duct for the separator
Kits for determination of thromboxane B.sub.2 metabolite and optimizing aspirin dosage
Porous polymers
Operating a communications network
Data storage system with primary and secondary compression engines