Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Method for prediction of bone fractures by osteocalcin measurements










Image Number 2 for United States Patent #6967081.

This invention concerns a method for the assessment of bone fragility and fracture risk, or osteoporosis, in a person. In said method, the concentration of gamma-carboxylated osteocalcin (COC) and optionally also the concentration of intact or total osteocalcin (IOC or TOC, respectively) in a body fluid sample of said person is measured. The concentration of gamma-carboxylated osteocalcin (COC) so obtained is compared to the mean concentration of gamma-carboxylated osteocalcin (mean COC) in similar body fluid samples of the population of the same age and sex. Alternatively, the determined ratio COC/IOC or COC/TOC for said person, is compared to the mean ratio COC/IOC or COC/TOC, (mean ratio COC/IOC or mean ratio COC/TOC) determined from measurements in similar body fluid samples of the population of the same age and sex. A measured COC that is lower than the mean COC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. Preferably, a determined ratio COC/TOC that is lower than the mean ratio COC/TOC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. The invention concerns further kits for use in the assessment according to this invention.








 
 
  Recently Added Patents
Communications in an asynchronous cellular wireless network
Method for adapting a contact point of a clutch in a drivetrain of a motor vehicle
Information recording medium and information processing method for accessing content with license or copyright protection
Systems and methods for building axes, co-axes and paleo-geographic coordinates related to a stratified geological volume
Mirac proteins
Optical coherence tomography with multiple sample arms
Method and apparatus for re-routing calls in a packet network during failures
  Randomly Featured Patents
Semiconductor device with via hole for electric connection
Method and system for a persistent request generated by a wireless device, executed remotely and output to configurable local resources
Scuba tank mounting mechanism
Meat tenderizing roller
Methods and apparatus for controlling operation of a link layer controller based upon a state of connection between multiple electronic apparatus
Insertion assembly of an endoscope
Process for bleaching wood pulp with hydrogen peroxide
Fish attracting device
Methods of using shape memory alloys for buttress attachment
Multivalued semiconductor read only storage device and method of driving the device and method of manufacturing the device