Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Method for prediction of bone fractures by osteocalcin measurements










Image Number 2 for United States Patent #6967081.

This invention concerns a method for the assessment of bone fragility and fracture risk, or osteoporosis, in a person. In said method, the concentration of gamma-carboxylated osteocalcin (COC) and optionally also the concentration of intact or total osteocalcin (IOC or TOC, respectively) in a body fluid sample of said person is measured. The concentration of gamma-carboxylated osteocalcin (COC) so obtained is compared to the mean concentration of gamma-carboxylated osteocalcin (mean COC) in similar body fluid samples of the population of the same age and sex. Alternatively, the determined ratio COC/IOC or COC/TOC for said person, is compared to the mean ratio COC/IOC or COC/TOC, (mean ratio COC/IOC or mean ratio COC/TOC) determined from measurements in similar body fluid samples of the population of the same age and sex. A measured COC that is lower than the mean COC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. Preferably, a determined ratio COC/TOC that is lower than the mean ratio COC/TOC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. The invention concerns further kits for use in the assessment according to this invention.








 
 
  Recently Added Patents
Garden tool handle
Wound dressings
Mobile interactive kiosk method
Thermally efficient busway
Cable exit trough with insert
Systems and methods for DC-to-DC converter control
Gestures for presentation of different views of a system diagram
  Randomly Featured Patents
Post-release adjustment of interferometric modulator reflectivity
Method and apparatus for determining a cell density of a honeycomb body, in particular for an exhaust gas catalytic converter
Method for assigning values of service attributes to transmissions, radio access networks and network elements
Arc extinguishing device of circuit breaker for manual motor starter
Multi-mode lighter
Process for preparing rigid foamed materials containing urethane groups
Network cabinet
Machine for applying adhesive to preset regions of products in general
Semiconductor laser device, semiconductor laser module, Raman amplifier using the device or module, and method for forming a suitable current blocking layer
Lockbar for a seatbelt retractor