Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Everninomicin biosynthetic genes










Image Number 107 for United States Patent #6861513.

This invention is directed to nucleic acids which encode the proteins that direct the synthesis of the orthosomycin everninomicin and to use of the nucleic acids and proteins to produce compounds exhibiting antibiotic activity based on the everninomycin structure. The DNA sequence for the gene clusters responsible for encoding everninomicin biosynthetic genes, which provide the machinery for producing everninomicin, are provided. Thus, this invention provides the nucleic acid sequences needed to synthesize novel everninomicin-related compounds based on everninomicin, arising from modifications of the DNA sequence designed to change glycosyl and modified orsellinic acid groups contained in everninomicin. A. Micromonospora site-specific integrase gene is also provided, which can be incorporated in a vector for integration into any actinomycete, and, particularly into Monospora. Thus, the invention further provides methods for introducing heterologous genes into an actinomycete chromosome using this particular vector.








 
 
  Recently Added Patents
Sample chamber for laser ablation inductively coupled plasma mass spectroscopy
Oil extractor and the preparation method thereof
Communication system, authentication device, control server, communication method, and program
Color image display device, color filter substrate, color pixel array substrate, and electronic device
Method and device for generating low-jitter clock
Clamp for fence panels
Ion beam system and method of operating ion beam system
  Randomly Featured Patents
Plumbing control
Cleaning device, and image forming apparatus, process cartridge, and intermediate transfer unit each including the cleaning device
Combination ball mark repair tool and golf green slope indicator
Look-up table circuits and field programmable gate array
Set of key buttons for a handset
Crystallization process
Server enclosure and server enclosure assembly
Microwave induced pyrolysis reactor and method
Radiation treatable printing plate
Antenna device and a method of making the antenna