Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Everninomicin biosynthetic genes










Image Number 107 for United States Patent #6861513.

This invention is directed to nucleic acids which encode the proteins that direct the synthesis of the orthosomycin everninomicin and to use of the nucleic acids and proteins to produce compounds exhibiting antibiotic activity based on the everninomycin structure. The DNA sequence for the gene clusters responsible for encoding everninomicin biosynthetic genes, which provide the machinery for producing everninomicin, are provided. Thus, this invention provides the nucleic acid sequences needed to synthesize novel everninomicin-related compounds based on everninomicin, arising from modifications of the DNA sequence designed to change glycosyl and modified orsellinic acid groups contained in everninomicin. A. Micromonospora site-specific integrase gene is also provided, which can be incorporated in a vector for integration into any actinomycete, and, particularly into Monospora. Thus, the invention further provides methods for introducing heterologous genes into an actinomycete chromosome using this particular vector.








 
 
  Recently Added Patents
Surveillance apparatus and method for wireless mesh network
Mobile terminal device capable of more effectively utilizing operation portions, conductive portion, operation detecting unit, power supply unit, and signal processing unit
Method for execution upon processing of at least one histological sample
System and method for wireless messaging in a wireless communication system
Analysis, secure access to, and transmission of array images
Reduced sorbent utilization for circulating dry scrubbers
Inspection tool for top guides of a boiling water reactor
  Randomly Featured Patents
Process for treating electrolytic solution and apparatus therefor
Traverse rod assembly
Self-shielded coil with non-inductive winding
Compact drive-through vehicle wash
Method for producing linear organopolysilexanes with .alpha., .omega., terminal Si-linked alkenyl groups or .alpha., .omega. terminal-linked hydrogen atoms
Mobile scenery arrangement
Battery terminal connection cable
Frame for phonograph record jacket
Process for fabricating chip package structure
Slitter machine for tab lock cases