Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Everninomicin biosynthetic genes










Image Number 107 for United States Patent #6861513.

This invention is directed to nucleic acids which encode the proteins that direct the synthesis of the orthosomycin everninomicin and to use of the nucleic acids and proteins to produce compounds exhibiting antibiotic activity based on the everninomycin structure. The DNA sequence for the gene clusters responsible for encoding everninomicin biosynthetic genes, which provide the machinery for producing everninomicin, are provided. Thus, this invention provides the nucleic acid sequences needed to synthesize novel everninomicin-related compounds based on everninomicin, arising from modifications of the DNA sequence designed to change glycosyl and modified orsellinic acid groups contained in everninomicin. A. Micromonospora site-specific integrase gene is also provided, which can be incorporated in a vector for integration into any actinomycete, and, particularly into Monospora. Thus, the invention further provides methods for introducing heterologous genes into an actinomycete chromosome using this particular vector.








 
 
  Recently Added Patents
Lightning-protective explosion-preventive fastener
Image forming apparatus, control method of image forming apparatus, and storage medium
Methods for diagnosing irritable bowel syndrome
Semiconductor assembly and semiconductor package including a solder channel
(4940
Minimizing mismatch during compensation
Semiconductor device and method of manufacturing the same
  Randomly Featured Patents
Latent, curable, catalyzed mixtures of epoxy-containing and phenolic-hydroxyl-containing compounds containing compounds or complexes formed from contacting organic phosphines or arsines with
Media player and control method thereof
Dual filter assembly for a vacuum cleaner
Hydrodynamic type porous oil-impregnated bearing
Composite connector assembly and power supply apparatus having such composite connector assembly
Anaerobic/aerobic decontamination of DDT contaminated soil by repeated anaerobic/aerobic treatments
Method for catalytically purifying exhaust gas
Hybrid space vector PWM schemes for interleaved three-phase converters
Self-adjusting locking pliers
Wheeled plant pot