Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Everninomicin biosynthetic genes










Image Number 107 for United States Patent #6861513.

This invention is directed to nucleic acids which encode the proteins that direct the synthesis of the orthosomycin everninomicin and to use of the nucleic acids and proteins to produce compounds exhibiting antibiotic activity based on the everninomycin structure. The DNA sequence for the gene clusters responsible for encoding everninomicin biosynthetic genes, which provide the machinery for producing everninomicin, are provided. Thus, this invention provides the nucleic acid sequences needed to synthesize novel everninomicin-related compounds based on everninomicin, arising from modifications of the DNA sequence designed to change glycosyl and modified orsellinic acid groups contained in everninomicin. A. Micromonospora site-specific integrase gene is also provided, which can be incorporated in a vector for integration into any actinomycete, and, particularly into Monospora. Thus, the invention further provides methods for introducing heterologous genes into an actinomycete chromosome using this particular vector.








 
 
  Recently Added Patents
Control apparatus and control method
Method of applying a spherical correction to map data for rendering direction-of-travel paths on a wireless communications device
Resuming piecewise calibration of a real-time-clock unit after a measured offset that begins at the next calibration period
Optical angular position detection apparatus and method
Image processing apparatus, method, and storage medium for performing soft proof processing
Correction information calculating device, image processing apparatus, image display system, and image correcting method
Precoding codebooks for MIMO communication systems
  Randomly Featured Patents
Apparatus for manipulating vehicular devices
Device for cutting welded wire structures
Bucky paper as a support membrane in retinal cell transplantation
Method and device for drawing wire into a shearing station of a forming press
Plasma processing apparatus
Method and apparatus for ascertaining the capacity of a network switch
Weather tracking and display system and method
Process for the production of boehmitic aluminas
Thiazolyl urea compounds and methods of uses
Modular belt carrier for electronic components