Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Probe composition comprising a binding polymer and polymer chain and methods of use










Image Number 13 for United States Patent #6756204.

Method and composition for detecting one or more selected polynucleotide regions in a target polynucleotide. In the method, a mixture of sequence-specific probes are reacted with the target polynucleotide under hybridization conditions, and the hybridized probes are treated to selectively modify those probes which are bound to the target polynucleotide in a base-specific manner. The resulting labeled probes include a polymer chain which imparts to each different-sequence probe, a distinctive ratio of charge/translational frictional drag, and a detectable label. The labeled probes are fractionated by electrophoresis in a non-sieving matrix, and the presence of one or more selected sequences in the target polynucleotide are detected according to the observed electrophoretic migration rates of the labeled probes in a non-sieving medium.








 
 
  Recently Added Patents
Enhancement of semiconducting photovoltaic absorbers by the addition of alkali salts through solution coating techniques
Integrated bug tracking and testing
Storing a location within metadata of visual media
Advertising system and method
Cell reselection and handover with multimedia broadcast/multicast service
Touch screen panel
Control system for shifting an automatic transmission
  Randomly Featured Patents
Antenna structures having adjustable radiation characteristics
Circuit for operating a flight navigation indicator
Combined coupling and air nozzle
Set of paving stones in an arrangement
Variable impedance device and circuit for sensing adjustment thereof
Cardiac visualization systems for displaying 3-D images of cardiac voxel intensity distributions with optional physician interactive boundary tracing tools
Agricultural implement, in particular a mowing machine
Two-phase cooling system for a laptop computer lid
Medical gamma ray imaging
Premix storage hopper