Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Probe composition comprising a binding polymer and polymer chain and methods of use










Image Number 13 for United States Patent #6756204.

Method and composition for detecting one or more selected polynucleotide regions in a target polynucleotide. In the method, a mixture of sequence-specific probes are reacted with the target polynucleotide under hybridization conditions, and the hybridized probes are treated to selectively modify those probes which are bound to the target polynucleotide in a base-specific manner. The resulting labeled probes include a polymer chain which imparts to each different-sequence probe, a distinctive ratio of charge/translational frictional drag, and a detectable label. The labeled probes are fractionated by electrophoresis in a non-sieving matrix, and the presence of one or more selected sequences in the target polynucleotide are detected according to the observed electrophoretic migration rates of the labeled probes in a non-sieving medium.








 
 
  Recently Added Patents
Phospholipid-based powders for drug delivery
Methods and systems for temporarily sharing position data between mobile-device users
Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
6-O-substituted benzoxazole and benzothiazole compounds and methods of inhibiting CSF-1R signaling
Plural component proportioner
Monitoring agent programs in a distributed computing platform
Near-field optical disk having surface plasmon amplification by stimulated emission of radiation
  Randomly Featured Patents
Method to integrate user data into uncompressed audio data
Power transmitting device
Torsionally reacting spring made of a bulk-solidifying amorphous metallic alloy
Directing cannula for an optical diagnostic system
Protection shoe for the paw of a dog
Baby feeding bottle sterilizer or similar article
Footed dessert cup
Air conditioning apparatus with indoor units installed on ceiling and floor in room
Bed
Trap-based mechanism for tracking accesses of logical components