Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Probe composition comprising a binding polymer and polymer chain and methods of use










Image Number 13 for United States Patent #6756204.

Method and composition for detecting one or more selected polynucleotide regions in a target polynucleotide. In the method, a mixture of sequence-specific probes are reacted with the target polynucleotide under hybridization conditions, and the hybridized probes are treated to selectively modify those probes which are bound to the target polynucleotide in a base-specific manner. The resulting labeled probes include a polymer chain which imparts to each different-sequence probe, a distinctive ratio of charge/translational frictional drag, and a detectable label. The labeled probes are fractionated by electrophoresis in a non-sieving matrix, and the presence of one or more selected sequences in the target polynucleotide are detected according to the observed electrophoretic migration rates of the labeled probes in a non-sieving medium.








 
 
  Recently Added Patents
Permitting access of slave device from master device based on process ID's
Information processing apparatus and display control method
Automated hotfix handling model
Antagonists of the glucagon receptor
Systems and methods for updating a data store using a transaction store
Wide viewing angle indicators for network devices
SRAM cells using shared gate electrode configuration
  Randomly Featured Patents
Controller of internal combustion engine
Substituted 2-thio-3,5-dicyano-4-aryl-6-aminopyridines and their use
Component object model communication method for a control system
One-piece trigger sprayer housing
Integrated circuit for receiving a data stream
Method of manufacturing a semiconductor device
Resonator use in the print field
Lithographic apparatus, illumination system and filter system
Gas burner having a fixed head burner with a quartz nozzle, a spring and an end cap
Amino acid mimetic copolymers and medical devices coated with the copolymers