Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Methods of identifying compounds that bind to target species under isothermal denaturing conditions










Image Number 4 for United States Patent #6713260.

The present invention provides a method for identifying a test compound that binds to a target species. The method includes: incubating at least one test mixture under isothermal denaturing conditions, each test mixture comprising at least one test compound, and at least one target species, wherein the isothermal denaturing conditions are effective to cause at least a portion of the target species to denature to a measurable extent; detecting a denaturation signal of each target species in the presence of the at least one test compound by a change in the diffusion properties of the target molecule using fluorescence correlation spectroscopy; and comparing the denaturation signal of each target species in the presence of at least one test compound with a denaturation signal of the same target species in the absence of the at least one test compound under the same isothermal denaturing conditions.








 
 
  Recently Added Patents
Device and method to automatically configure port forwarding
Heap/stack guard pages using a wakeup unit
Methods and systems for determining the reliability of transaction
Soybean variety XB51J12
Wafer recycling method
Recovering a database to any point-in-time in the past with guaranteed data consistency
Listing recommendation using generation of a user-specific query in a network-based commerce system
  Randomly Featured Patents
Tetrazolyl derivatives of .beta.-lactams useful as elastase inhibitors
Void detection in metallization patterns
Fe based soft magnetic alloy, magnetic materials containing same, and magnetic apparatus using the magnetic materials
Limited use DVD-video disc
Method and system for processing electronic search expressions
Power supply intercept with reference output
Biomaterials based on hyaluronic acid for the anti-angiogenic therapy in the treatment of tumors
Method and system for automatically adding generic change log to legacy application
Rear wheel steering mechanism for motor vehicle
Suture retaining clip