Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Methods of affecting intracellular phosphorylation of tyrosine using phosphorothioate oligonucleotides, and antiangiogenic and antiproliferative uses thereof










Image Number 10 for United States Patent #6030955.

The present invention provides methods of stimulating or inhibiting intracellular phosphorylation of tyrosine by a heparin-binding receptor which comprises contacting a cell having on its surface the heparin-binding receptor with a phosphorothioate oligonucleotide moiety of suitable length and base composition, such phosphorothioate oligonucleotide moiety being present in an effective amount. The invention further provides a method of inhibiting the formation of blood vessels in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition. The invention also provides a method of inhibiting proliferation of cells having a malignant phenotype in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition.








 
 
  Recently Added Patents
Memory device having collaborative filtering to reduce noise
Sense-amplifier monotizer
Communications in an asynchronous cellular wireless network
Method and apparatus for optimizing paging in a communication network
Three-dimensional shape data processing apparatus and three-dimensional shape data processing method
Pyrrolidine derivatives, pharmaceutical compositions containing the same, and methods of using the same
Benzimidazole inhibition of biofilm formation
  Randomly Featured Patents
Mask-patterns including intentional breaks
Light-emitting diode based traffic light
Window for a computer display screen
Identity card, information carrier and housing designed for its application
Fastener for securing electronic device and computer utilizing the same
Personalized audio system and method
Common mode feedback technique for a low voltage charge pump
Clamping device
Detecting, assessing and managing extreme epileptic events
Spade terminal