Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Methods of affecting intracellular phosphorylation of tyrosine using phosphorothioate oligonucleotides, and antiangiogenic and antiproliferative uses thereof










Image Number 10 for United States Patent #6030955.

The present invention provides methods of stimulating or inhibiting intracellular phosphorylation of tyrosine by a heparin-binding receptor which comprises contacting a cell having on its surface the heparin-binding receptor with a phosphorothioate oligonucleotide moiety of suitable length and base composition, such phosphorothioate oligonucleotide moiety being present in an effective amount. The invention further provides a method of inhibiting the formation of blood vessels in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition. The invention also provides a method of inhibiting proliferation of cells having a malignant phenotype in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition.








 
 
  Recently Added Patents
Memristive junction with intrinsic rectifier
Data processing circuit with arbitration between a plurality of queues
Block polymers and their process of preparation
Bipolar junction transistor with a self-aligned emitter and base
Method for growing group III-nitride crystals in supercritical ammonia using an autoclave
Resonant conversion system with over-current protection processes
Clock phase recovery apparatus
  Randomly Featured Patents
Integral center plane balancing of a rotating electric device
Microwave oven with radiant and convectional heating apparatus
Process for the preparation of candesartan cilexetil
Optical waveguide device and method for connecting optical waveguide and optical fiber using the optical waveguide device
K99-5041 substance and production thereof
Brief case with recessed handle
Hopper spreader/sprayer apparatus
Central office control of receive and transmit handset volume
Method of using a filter aid protein-polysaccharide complex composition
Method of applying a repair clamp to a pipe