Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Methods of affecting intracellular phosphorylation of tyrosine using phosphorothioate oligonucleotides, and antiangiogenic and antiproliferative uses thereof










Image Number 10 for United States Patent #6030955.

The present invention provides methods of stimulating or inhibiting intracellular phosphorylation of tyrosine by a heparin-binding receptor which comprises contacting a cell having on its surface the heparin-binding receptor with a phosphorothioate oligonucleotide moiety of suitable length and base composition, such phosphorothioate oligonucleotide moiety being present in an effective amount. The invention further provides a method of inhibiting the formation of blood vessels in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition. The invention also provides a method of inhibiting proliferation of cells having a malignant phenotype in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition.








 
 
  Recently Added Patents
Manufacturing method power semiconductor device
Food safety printer
Newly identified human rhinovirus of HRV-C and methods and kits for detecting HRV-Cs
Display screen with graphical user interface
Label with surface ornamentation
Method and apparatus for secure transfer and playback of multimedia content
Gate timing for short servo wedge in disk memory systems
  Randomly Featured Patents
Surveying of boreholes
Earth boring auger
Method for hierarchical parasitic extraction of a CMOS design
Beverage container with cap
Device for measuring the wake of a sailing model
Plant fatty acid synthases
Context driven image mining to generate image-based biomarkers
Method and apparatus for preventing stranding elements from crossing during a stranding process
LED light bulb
Non-contacting measuring system for precision characteristics, particularly of industrial robots