Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Methods of affecting intracellular phosphorylation of tyrosine using phosphorothioate oligonucleotides, and antiangiogenic and antiproliferative uses thereof










Image Number 10 for United States Patent #6030955.

The present invention provides methods of stimulating or inhibiting intracellular phosphorylation of tyrosine by a heparin-binding receptor which comprises contacting a cell having on its surface the heparin-binding receptor with a phosphorothioate oligonucleotide moiety of suitable length and base composition, such phosphorothioate oligonucleotide moiety being present in an effective amount. The invention further provides a method of inhibiting the formation of blood vessels in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition. The invention also provides a method of inhibiting proliferation of cells having a malignant phenotype in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition.








 
 
  Recently Added Patents
Systems and methods for providing a shared folder via television
Audio conversation apparatus
Liquid composite compositions using non-volatile liquids and nanoparticles and uses thereof
Hair care composition
Method and system for modularized configurable connector system for ethernet applications
Case for electronic device
Method of operating an election ballot printing system
  Randomly Featured Patents
Floating threshold for data detection in a RFID tag
Filtration system
Gamma camera
Methods and systems for tracking RFID devices
Semiconductor memory device with high operating current and method of manufacturing the same
Clip-hanger for suspending articles from walls
Fiber reinforced plastic (FRP) composite structural system for decks, docks, boardwalks, walkways, spa decks, hot tub decks and gazebos and components therefore and method of making same
Low molecular weight inhibitors of complement proteases
Masonry weep hole insert
Apparatus and method for evaluating quality of granular object