Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Methods of affecting intracellular phosphorylation of tyrosine using phosphorothioate oligonucleotides, and antiangiogenic and antiproliferative uses thereof










Image Number 10 for United States Patent #6030955.

The present invention provides methods of stimulating or inhibiting intracellular phosphorylation of tyrosine by a heparin-binding receptor which comprises contacting a cell having on its surface the heparin-binding receptor with a phosphorothioate oligonucleotide moiety of suitable length and base composition, such phosphorothioate oligonucleotide moiety being present in an effective amount. The invention further provides a method of inhibiting the formation of blood vessels in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition. The invention also provides a method of inhibiting proliferation of cells having a malignant phenotype in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition.








 
 
  Recently Added Patents
Server system and method for discovering digital assets in enterprise information systems
Lateral flow test kit and method for detecting an analyte
Cantilevered probe detector with piezoelectric element
Interaction analysis and prioritization of mobile content
Process for the preparation of ethylene homopolymers or copolymers in a high-pressure reactor controlled by a model based predictive controller
Mobile camera localization using depth maps
Writing implement
  Randomly Featured Patents
Apparatus for lighting
Grip assembly for attaching an electric cord to an electric appliance, and the like
Combination EAS and RFID label or tag using a hybrid RFID antenna
Suction relief apparatus
Waterless lithographic printing plates
Content distribution system, distribution method, content processing device, and processing method
Ski boot, in particular for ski mountaineering
Cylinder deactivation via exhaust valve deactivation and intake cam retard
Method for fabricating semiconductor device
Method for making curable coatings