Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Methods of affecting intracellular phosphorylation of tyrosine using phosphorothioate oligonucleotides, and antiangiogenic and antiproliferative uses thereof










Image Number 10 for United States Patent #6030955.

The present invention provides methods of stimulating or inhibiting intracellular phosphorylation of tyrosine by a heparin-binding receptor which comprises contacting a cell having on its surface the heparin-binding receptor with a phosphorothioate oligonucleotide moiety of suitable length and base composition, such phosphorothioate oligonucleotide moiety being present in an effective amount. The invention further provides a method of inhibiting the formation of blood vessels in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition. The invention also provides a method of inhibiting proliferation of cells having a malignant phenotype in a subject which comprises administering to the subject an amount of a phosphorothioate oligonucleotide moiety of suitable length and base composition.








 
 
  Recently Added Patents
Battery grid
Spark plug
Method of producing probabilities of being a template shape
Method and apparatus for reducing and controlling highway congestion to save on fuel costs
Compounds, compositions and methods for reducing lipid levels
System for wireless local area network (WLAN) transmission and for coexistence of WLAN and another type of wireless transmission and methods thereof
Virtual image display device and manufacturing method of virtual image display device
  Randomly Featured Patents
Segmented bar-in-bar target
Cast film made from metallocene-catalyzed polypropylene
Ventilated end turns for rotor windings of a dynamoelectric machine
Detergent builders
Pass through via technology for use during the manufacture of a semiconductor device
1,2-Pentamethylene-1,4-dihydropyridine derivatives
Benzothiophene compounds, compositions, and methods
Clamping apparatus for press brake
Cosmetic composition containing at least one surface-active agent of the alkylpolyglycoside and/or polyglycerolated type and at least one crosslinked copolymer of maleic anhydride/(C1-C5) alky
Selective deghosting of plural GCR-containing video signals