Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Method of producing hepatocycte growth factor/scatter factor and related cell lines










Image Number 15 for United States Patent #5871959.

A method of preventing tumor cell metastasis by inhibiting the binding of hepatocyte growth factor/scatter factor ("HGF/SF") with met proto-oncogene protein is described. A method of producing HGF/SF and a cell line for the production of HGF/SF are also described. The met proto-oncogene tyrosine kinase receptor (Met) and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), ordinarily constitute a paracrine signalling system in which cells of mesenchymal origin produce the ligand, which binds to the receptor that is predominantly expressed in cells of epithelial origin. The method of the present invention disrupts the Met-HGF/SF autocrine signaling that contributes to the tumorigenic process in tumors of mesenchymal origin, such as sarcomas.








 
 
  Recently Added Patents
Buried object detection in GPR images
TRPM8 antagonists and their use in treatments
Monitoring cloud-runtime operations
Method and system for detecting target objects
Techniques for data assignment from an external distributed file system to a database management system
Method and apparatus for reducing power consumption used in communication system having time slots
Fabricated leaf tea products
  Randomly Featured Patents
Systems and methods for variable control of power dissipation in a pipelined processor
Mail box support apparatus
Pager broadcast system
Spray shield for automotive vehicles
Mold for shaping glass
High load connection system
Pulse radar device having pulsed storage devices arranged in the signal analysis component
Wireless personal paging, communications, and locating system
Mower deck suspension mechanism
Fluid component detection method with feedback