Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Method of producing hepatocycte growth factor/scatter factor and related cell lines










Image Number 15 for United States Patent #5871959.

A method of preventing tumor cell metastasis by inhibiting the binding of hepatocyte growth factor/scatter factor ("HGF/SF") with met proto-oncogene protein is described. A method of producing HGF/SF and a cell line for the production of HGF/SF are also described. The met proto-oncogene tyrosine kinase receptor (Met) and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), ordinarily constitute a paracrine signalling system in which cells of mesenchymal origin produce the ligand, which binds to the receptor that is predominantly expressed in cells of epithelial origin. The method of the present invention disrupts the Met-HGF/SF autocrine signaling that contributes to the tumorigenic process in tumors of mesenchymal origin, such as sarcomas.








 
 
  Recently Added Patents
Synthetic refrigeration oil composition for HFC applications
Methods and systems for improved engine speed control during engine starting
Matching a usage history to a new cloud
Identification of electrical grid phase information for end-points in a grid network
Cable preparation tool
Elegant solutions for fingerprint image enhancement
Probiotic Bifidobacterium strains
  Randomly Featured Patents
Multistrand suture package
Sensor device having a pathway and a sealed cavity
Chain constructed structure
Light source device
Heat exchanger and associated method
Multi chamber capture detection
Injection molding machine which carries out controlling of closing operation of a check ring
Venetian blind cell layout for RF power transistor
Front face of a vehicle wheel
Electrically conductive fillers