Resources Contact Us Home
Method of producing hepatocycte growth factor/scatter factor and related cell lines

Image Number 15 for United States Patent #5871959.

A method of preventing tumor cell metastasis by inhibiting the binding of hepatocyte growth factor/scatter factor ("HGF/SF") with met proto-oncogene protein is described. A method of producing HGF/SF and a cell line for the production of HGF/SF are also described. The met proto-oncogene tyrosine kinase receptor (Met) and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), ordinarily constitute a paracrine signalling system in which cells of mesenchymal origin produce the ligand, which binds to the receptor that is predominantly expressed in cells of epithelial origin. The method of the present invention disrupts the Met-HGF/SF autocrine signaling that contributes to the tumorigenic process in tumors of mesenchymal origin, such as sarcomas.

  Recently Added Patents
TV wall mount
Method, apparatus, computer program, and computer readable storage media for controlling the insertion of tab sheets into a print job
Credit flow control scheme in a router with flexible link widths utilizing minimal storage
Random sampling for geophysical acquisitions
Asynchronous loading of scripts in web pages
Architecture, system and method for testing resistive type memory
Generator with a segmented stator
  Randomly Featured Patents
Disk player for playing back more than one kind of disk
Cap funnel
Information retrieval
Cosmetic container with mirror
Self-pumping hydropneumatic spring strut with internal level control
Attic air conditioning system
Whisker reinforced ceramics and a method of clad/hot isostatic pressing same
Routing internet communications using network coordinates
Method of making a semiconductor device
Low latency synchronous memory performance switching using update control