Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Method of producing hepatocycte growth factor/scatter factor and related cell lines










Image Number 15 for United States Patent #5871959.

A method of preventing tumor cell metastasis by inhibiting the binding of hepatocyte growth factor/scatter factor ("HGF/SF") with met proto-oncogene protein is described. A method of producing HGF/SF and a cell line for the production of HGF/SF are also described. The met proto-oncogene tyrosine kinase receptor (Met) and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), ordinarily constitute a paracrine signalling system in which cells of mesenchymal origin produce the ligand, which binds to the receptor that is predominantly expressed in cells of epithelial origin. The method of the present invention disrupts the Met-HGF/SF autocrine signaling that contributes to the tumorigenic process in tumors of mesenchymal origin, such as sarcomas.








 
 
  Recently Added Patents
Node and wireless sensor network comprising the node
Method and system for determining a suppression factor of a suppression system and a lithographic apparatus
Method and system for quantifying viewer awareness of advertising images in a video source
Business card assembly
System and method for enhancing buyer and seller interaction during a group-buying sale
Systems and methods for switching supply load current estimation
Protein purification
  Randomly Featured Patents
Method for treating cotyledonous plants
DPF heater attachment mechanisms
Method for producing thin steel sheet of high magnetic permeability
Liquid ring pump
Analgesic composition and method of relieving pain
Tissue treatment device and method
Apparatus and method for a blower cover
Treatment of herpes simplex infections
Electric connector
Method for assaying antibodies in body fluids by immune reaction with glycoprotein 2 (GP2) from zymogenic granules of the pancreas for the differential diagnosis of inflammatory intestinal dis