Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Treatment of vascular injury using vascular endothelial growth factor










Image Number 4 for United States Patent #5830879.

The present invention provides a method for inducing reendothelialization of the lining of an injured blood vessel comprising contacting the injured portion of the vessel with nucleic acid encoding an endothelial cell mitogen such as vascular endothelial growth factor (VEGF) operably linked to a promoter to result in expression of the mitogen when delivered to the cells at the site of vascular injury. The resulting reendothelialization of the injured blood vessel inhibits smooth muscle cell proliferation and consequently reduces restenosis. The methods of the present invention may be used to treat any blood vessel injury that results in denuding of the endothelial lining of the vessel wall, including, for example, those injuries resulting from balloon angioplasty and deployment of endovascular stents.








 
 
  Recently Added Patents
Imaging device and imaging method
Bias voltage generating circuit and switching power supply thereof
Keypoint descriptor generation by complex wavelet analysis
Latch-up free ESD protection
Device and implantation system for electrical stimulation of biological systems
Light emitting device and electronic device
Cleaning device, and image forming apparatus, process cartridge, and intermediate transfer unit each including the cleaning device
  Randomly Featured Patents
Process for producing L-isoleucine and ethionine by isoleucine analog resistant strains of E. coli
Digital camera
Thermoplastic, polymeric materials providing high IR absorption, method for the production thereof, and use thereof
Chip-scale semiconductor die packaging method
Prosthetic heart valve
Sewing device for producing piped openings in sewing material
Print system, information processing apparatus, and information processing method, including log information
Reduction gear of electronic wristwatch with stepping motor and sweep second hand
Manual dual purpose garden tool
Method of recording image signals of photographic pictures