Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Treatment of vascular injury using vascular endothelial growth factor










Image Number 4 for United States Patent #5830879.

The present invention provides a method for inducing reendothelialization of the lining of an injured blood vessel comprising contacting the injured portion of the vessel with nucleic acid encoding an endothelial cell mitogen such as vascular endothelial growth factor (VEGF) operably linked to a promoter to result in expression of the mitogen when delivered to the cells at the site of vascular injury. The resulting reendothelialization of the injured blood vessel inhibits smooth muscle cell proliferation and consequently reduces restenosis. The methods of the present invention may be used to treat any blood vessel injury that results in denuding of the endothelial lining of the vessel wall, including, for example, those injuries resulting from balloon angioplasty and deployment of endovascular stents.








 
 
  Recently Added Patents
Circuit arrangement having a load transistor and a voltage limiting circuit and method for driving a load transistor
Systems and methods for sorting particles
Interactive program guide systems and processes
Field emission cathode device and field emission display using the same
Buckle (tube)
Flash multi-level threshold distribution scheme
Multi-chip package with a supporting member and method of manufacturing the same
  Randomly Featured Patents
Apparatus and method to identify the maximum operating frequency of a processor
Receiver-driven layered error correction multicast over heterogeneous packet networks
Press section of a paper machine
Damage evaluation method of compound semiconductor member, production method of compound semiconductor member, gallium nitride compound semiconductor member and gallium nitride compound semico
Matrix and method of using an aliphatic alcohol coated silica glass matrix
Method for reducing moisture loss in cooked meats
Disposable dental syringe
DC-DC converter with improved dynamic response
Variable/personalized colorization printing using tone reproduction curves
Apparatus and methods for making simultaneous electrical connections