Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Treatment of vascular injury using vascular endothelial growth factor










Image Number 4 for United States Patent #5830879.

The present invention provides a method for inducing reendothelialization of the lining of an injured blood vessel comprising contacting the injured portion of the vessel with nucleic acid encoding an endothelial cell mitogen such as vascular endothelial growth factor (VEGF) operably linked to a promoter to result in expression of the mitogen when delivered to the cells at the site of vascular injury. The resulting reendothelialization of the injured blood vessel inhibits smooth muscle cell proliferation and consequently reduces restenosis. The methods of the present invention may be used to treat any blood vessel injury that results in denuding of the endothelial lining of the vessel wall, including, for example, those injuries resulting from balloon angioplasty and deployment of endovascular stents.








 
 
  Recently Added Patents
Method of processing data and display apparatus for performing the method
Automated hotfix handling model
Pyrrolidine derivatives, pharmaceutical compositions containing the same, and methods of using the same
Client-managed group communication sessions within a wireless communications system
Method and apparatus for determining storage capacity error for a data storage device
Sealing member for piezoelectric resonator device, and piezoelectric resonator device
Display fixture for highlighting products
  Randomly Featured Patents
Front body structure of automotive vehicle
Sanitary fitting
Heat pump and structure of extraction heat exchanger thereof
Collagen-like polypeptides and biopolymers and nucleic acids encoding same
Wideband mud pump noise cancelation method for wellbore telemetry
Bicyclic compound
Overlay scan line processing
Driving intention estimation system, vehicle operation assistance system, and vehicle equipped therewith
Method for preparing an active substance of chemical cells
Drying scale with moveable radiating source and a method performed by the drying scale