Resources Contact Us Home
Treatment of vascular injury using vascular endothelial growth factor

Image Number 4 for United States Patent #5830879.

The present invention provides a method for inducing reendothelialization of the lining of an injured blood vessel comprising contacting the injured portion of the vessel with nucleic acid encoding an endothelial cell mitogen such as vascular endothelial growth factor (VEGF) operably linked to a promoter to result in expression of the mitogen when delivered to the cells at the site of vascular injury. The resulting reendothelialization of the injured blood vessel inhibits smooth muscle cell proliferation and consequently reduces restenosis. The methods of the present invention may be used to treat any blood vessel injury that results in denuding of the endothelial lining of the vessel wall, including, for example, those injuries resulting from balloon angioplasty and deployment of endovascular stents.

  Recently Added Patents
Compatibility check
Control device of hybrid vehicle
Braided pull tug pet toy
Apparatus and method for adapted deblocking filtering strength
Crystalline form of zofenopril calcium
Detecting patterns of abuse in a virtual environment
Fabric care compositions comprising front-end stability agents
  Randomly Featured Patents
Transmission system comprising a semiconductor laser and a fiber grating discriminator
Ergonomic finger guide for biometric finger scanner
Fire detector
Electronically controlled cryopump
Sewing machine with needle holder of needle interval adjustable type
Method and apparatus for protecting personnel and material from RF-based threats using ultra-wideband (UWB) transmission
Ink reservoir assembly for a pagewidth printhead
Soap dish
Pulse pumped catalyst heat exchanger
Ligand for CD7 and methods for use thereof