Resources Contact Us Home
Treatment of vascular injury using vascular endothelial growth factor

Image Number 4 for United States Patent #5830879.

The present invention provides a method for inducing reendothelialization of the lining of an injured blood vessel comprising contacting the injured portion of the vessel with nucleic acid encoding an endothelial cell mitogen such as vascular endothelial growth factor (VEGF) operably linked to a promoter to result in expression of the mitogen when delivered to the cells at the site of vascular injury. The resulting reendothelialization of the injured blood vessel inhibits smooth muscle cell proliferation and consequently reduces restenosis. The methods of the present invention may be used to treat any blood vessel injury that results in denuding of the endothelial lining of the vessel wall, including, for example, those injuries resulting from balloon angioplasty and deployment of endovascular stents.

  Recently Added Patents
Tomlinson Harashima precoding with additional receiver processing in a multi-user multiple-input multiple-output wireless transmission system
Cooling structure for electronic device
Preventative traffic congestion social networking improvement system within a community
Determining phase-specific parameters of a physiological variable
LED illumination systems
Accelerator for a read-channel design and simulation tool
  Randomly Featured Patents
Method and apparatus for joining components with multiple filler materials
Workably curing acrylic plastic
Dressing tool for grinding wheels
Temperature sensing tube for expansion valve
Manifold for maintaining a latch actuator under pressure and accommodating leaks
Method and apparatus for analyzing a pitched ball
Software updating system, software updating method, and software updating program
Thin film spin probe
System and method for central management of network and storage resources for a video surveillance system
Tire for motorcycle