Resources Contact Us Home
Treatment of vascular injury using vascular endothelial growth factor

Image Number 4 for United States Patent #5830879.

The present invention provides a method for inducing reendothelialization of the lining of an injured blood vessel comprising contacting the injured portion of the vessel with nucleic acid encoding an endothelial cell mitogen such as vascular endothelial growth factor (VEGF) operably linked to a promoter to result in expression of the mitogen when delivered to the cells at the site of vascular injury. The resulting reendothelialization of the injured blood vessel inhibits smooth muscle cell proliferation and consequently reduces restenosis. The methods of the present invention may be used to treat any blood vessel injury that results in denuding of the endothelial lining of the vessel wall, including, for example, those injuries resulting from balloon angioplasty and deployment of endovascular stents.

  Recently Added Patents
Communication apparatus, and method and program for controlling same
Using interrupted through-silicon-vias in integrated circuits adapted for stacking
Plants and seeds of corn variety CV778791
High productivity single pass scanning system
Transistor and display device
Methods of forming semiconductor devices having diffusion regions of reduced width
Invisible fence battery charger
  Randomly Featured Patents
Electric junction box for an automotive vehicle
State machine controlled dynamic distributed computing
Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
Method and apparatus for cutting a cylindrical material
Image pickup lens
High-voltage CMOS process
Curved conveyor
Information processing system, information processing method of information processing system, information processing apparatus, and information processing program
Image projector forming scrolling image
Identifying medium and identifying method for object