Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Treatment of vascular injury using vascular endothelial growth factor










Image Number 4 for United States Patent #5830879.

The present invention provides a method for inducing reendothelialization of the lining of an injured blood vessel comprising contacting the injured portion of the vessel with nucleic acid encoding an endothelial cell mitogen such as vascular endothelial growth factor (VEGF) operably linked to a promoter to result in expression of the mitogen when delivered to the cells at the site of vascular injury. The resulting reendothelialization of the injured blood vessel inhibits smooth muscle cell proliferation and consequently reduces restenosis. The methods of the present invention may be used to treat any blood vessel injury that results in denuding of the endothelial lining of the vessel wall, including, for example, those injuries resulting from balloon angioplasty and deployment of endovascular stents.








 
 
  Recently Added Patents
Method and apparatus for performing volume replication using unified architecture
Offset optimization system
Illumination apparatus
Pouch
System and method for managing individual use of a mobile telecommunications account
Methods and compositions for intraocular administration to treat ocular conditions
Status polling
  Randomly Featured Patents
Dual mode transmission system with switched linear amplifier
Topical immunotherapy and compositions for use therein
Photovoltaic device having light transmitting electrically conductive stacked films
Electric toothbrushes
Streptomyces metabolite
Outerwear garment
Audio and charging station for a handheld electronic device
Microwave method of making semiconductor members
Autofocus and/or autoscaling in telesurgery
Solar battery timepiece