Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Treatment of vascular injury using vascular endothelial growth factor










Image Number 4 for United States Patent #5830879.

The present invention provides a method for inducing reendothelialization of the lining of an injured blood vessel comprising contacting the injured portion of the vessel with nucleic acid encoding an endothelial cell mitogen such as vascular endothelial growth factor (VEGF) operably linked to a promoter to result in expression of the mitogen when delivered to the cells at the site of vascular injury. The resulting reendothelialization of the injured blood vessel inhibits smooth muscle cell proliferation and consequently reduces restenosis. The methods of the present invention may be used to treat any blood vessel injury that results in denuding of the endothelial lining of the vessel wall, including, for example, those injuries resulting from balloon angioplasty and deployment of endovascular stents.








 
 
  Recently Added Patents
Performance apparatus and electronic musical instrument
Method for detecting motion of an electrical device or apparatus
Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
Table base
Packaging for socks
Sensor packages and method of packaging dies of differing sizes
ESD protection circuit and ESD protection device thereof
  Randomly Featured Patents
Nipecotic acid derivatives as antithrombotic compounds
Method of creating an accurate bone and soft-tissue digital dental model
Shoe upper
Portable real-time high-resolution digital phase-stepping shearography with integrated excitation mechanisms
Fuzzy membership function circuit
Synthetic thermoplastic resin extruded foams and methods for producing the same
2-imino-1,3-thiazine derivatives
Memory module having on-package or on-module termination
Biomass growth control apparatus for fluid bed biological reactor
Method and device for diagnosing and distinguishing chest pain in early onset thereof