Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Treatment of vascular injury using vascular endothelial growth factor










Image Number 4 for United States Patent #5830879.

The present invention provides a method for inducing reendothelialization of the lining of an injured blood vessel comprising contacting the injured portion of the vessel with nucleic acid encoding an endothelial cell mitogen such as vascular endothelial growth factor (VEGF) operably linked to a promoter to result in expression of the mitogen when delivered to the cells at the site of vascular injury. The resulting reendothelialization of the injured blood vessel inhibits smooth muscle cell proliferation and consequently reduces restenosis. The methods of the present invention may be used to treat any blood vessel injury that results in denuding of the endothelial lining of the vessel wall, including, for example, those injuries resulting from balloon angioplasty and deployment of endovascular stents.








 
 
  Recently Added Patents
Permanent magnet axial field zeeman slower
Visual physician office systems and methods
Inhibitors of bacterial nitric oxide synthase, and related screening methods
Radiation-curable ink composition, ink jet recording method, and recorded matter
Firewall-tolerant voice-over-internet-protocol (VoIP) emulating SSL or HTTP sessions embedding voice data in cookies
Distortion estimation for quantized data
Dielectric insulation medium
  Randomly Featured Patents
Battery module
Apparatus and method for transmission of dynamic feedback channel information in a MIMO system
Backlight unit and display apparatus having the same
Perfect multidimensional spatial hashing
Control of water discharge system by reflected wave detection threshold(s)
Wick applicator for herbicides
Preparation of resin composition from cyclic polycarbonate oligomers from spirobiindane bisphenol
Wheel presetting apparatus
Engine valve actuation system
Broadband telecommunications system