Resources Contact Us Home
Treatment of vascular injury using vascular endothelial growth factor

Image Number 4 for United States Patent #5830879.

The present invention provides a method for inducing reendothelialization of the lining of an injured blood vessel comprising contacting the injured portion of the vessel with nucleic acid encoding an endothelial cell mitogen such as vascular endothelial growth factor (VEGF) operably linked to a promoter to result in expression of the mitogen when delivered to the cells at the site of vascular injury. The resulting reendothelialization of the injured blood vessel inhibits smooth muscle cell proliferation and consequently reduces restenosis. The methods of the present invention may be used to treat any blood vessel injury that results in denuding of the endothelial lining of the vessel wall, including, for example, those injuries resulting from balloon angioplasty and deployment of endovascular stents.

  Recently Added Patents
Process for recovering lithium from a brine
Reptile breeding tank
Methods and systems for network printing with user selectable settings
Process for producing thiophene compound and intermediate thereof
Method and apparatus for a cleanspace fabricator
Radiator grill for automobile
Semiconductor substrate with transistors having different threshold voltages
  Randomly Featured Patents
Ultraviolet microscope
Streamer cable multiplexing apparatus
Method for synthesizing 1,3-dihydroxytetramethyldisiloxane
Mechanical doll toy
Telescopic decorative shutter
N-benzyl-2,6-dinitro-3-amino-4-trifluoromethylanilines as plant growth regulants
Catalytic hydrocracking
Stuffing/dosing machine comprising a tilting hopper
Simple power MOSFET low side driver switch-off circuit with limited di/dt and fast response
Inkjet printhead with sandwiched nozzle film and method of manufacturing the same