Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Treatment of vascular injury using vascular endothelial growth factor










Image Number 4 for United States Patent #5830879.

The present invention provides a method for inducing reendothelialization of the lining of an injured blood vessel comprising contacting the injured portion of the vessel with nucleic acid encoding an endothelial cell mitogen such as vascular endothelial growth factor (VEGF) operably linked to a promoter to result in expression of the mitogen when delivered to the cells at the site of vascular injury. The resulting reendothelialization of the injured blood vessel inhibits smooth muscle cell proliferation and consequently reduces restenosis. The methods of the present invention may be used to treat any blood vessel injury that results in denuding of the endothelial lining of the vessel wall, including, for example, those injuries resulting from balloon angioplasty and deployment of endovascular stents.








 
 
  Recently Added Patents
Flood protection apparatus and container data center including the same
Anti-infective derivatives, method for the production thereof, pharmaceutical compositions containing same and uses of said derivatives in treatment
Metal-doped oxide, method of preparing the same, and solid oxide electrolyte using the metal-doped oxide
Method of enhancing corrosion resistance of hollow vessels
Controller interface providing improved data reliability
Faucet
Image forming apparatus, information processing method, and storage medium for generating screen information
  Randomly Featured Patents
Tryptophan overproducer mutants of cereal crops
Method of mounting universal mounting bracket for gas pump toppers
Light display
Assembly method for a voice coil motor
Output stage for an operational amplifier
Method and/or apparatus for motion estimation using a hierarchical search followed by a computation split for different block sizes
Process for preparing a storage stable premixed batter
Touch sensing apparatus with differential signal source
Apparatus for implantation and extraction of osteal prostheses
Sealing device for endoscopic probes