Resources Contact Us Home
Anti-proliferation domain of a human Bcl-2 and DNA encoding the same

Image Number 5 for United States Patent #5821082.

A domain of Bcl-2 that suppresses apoptosis by allowing cell survival permits cell proliferation when mutated. The wild type domain includes amino acid residues 51 to 97 (SEQ ID NO:13) of Bcl-2. Peptides including the domain and nucleotides encoding the domain are useful in molecular screening of human tumors for the presence of mutations that allow proliferation of cells that were otherwise marked for apoptosis. The peptides are also useful to screen for proteins that play a role in the modulation of cellular proliferation.

  Recently Added Patents
LCD television set capable of external connection with application processor
Motion-compensated prediction of inter-layer residuals
Process for production of nickel oxide-stabilized zirconia composite oxide
Probe for ultrasound diagnostic apparatus
Diazeniumdiolated phosphorylcholine polymers for nitric oxide release
5-HT.sub.3 receptor modulators, methods of making, and use thereof
Imaging apparatus having selection unit to select focus detection areas
  Randomly Featured Patents
Electrostatic loudspeaker having stationary electrodes formed as multiple sheets insulated from each other
Vane slots for a fluid power converter
Device to improve the mobility of towed howitzers
Mobile terminal device, mobile terminal method, mobile terminal program, and electronic money server
Substance inhalation system
Method for producing parts
Method and apparatus for manufacturing molded articles of alloyed material
Device for securing a wiper blade to an arm
Film forming method of silicon oxide film, silicon oxide film, semiconductor device, and manufacturing method of semiconductor device
Holder for filling syringe with radioactive liquid