Resources Contact Us Home
Anti-proliferation domain of a human Bcl-2 and DNA encoding the same

Image Number 5 for United States Patent #5821082.

A domain of Bcl-2 that suppresses apoptosis by allowing cell survival permits cell proliferation when mutated. The wild type domain includes amino acid residues 51 to 97 (SEQ ID NO:13) of Bcl-2. Peptides including the domain and nucleotides encoding the domain are useful in molecular screening of human tumors for the presence of mutations that allow proliferation of cells that were otherwise marked for apoptosis. The peptides are also useful to screen for proteins that play a role in the modulation of cellular proliferation.

  Recently Added Patents
Method of purifying crude acetone stream
Method and system for utilizing Perovskite material for charge storage and as a dielectric
Lighting control device and lighting control method
Semiconductor overlapped PN structure and manufacturing method thereof
Technique for skipping irrelevant portions of documents during streaming XPath evaluation
Distributed mobile access point acquisition
Centralized behavioral information system
  Randomly Featured Patents
Process for producing porous film or sheet
Power supply device for driving an amplifier
Glyph rendering quantization for subpixel positioning
Projection exposure apparatus
Controllable-force wire advance arrangement for electric-arc welding applications
Imaging device
Riser removal device
On die voltage regulator
Multilayer compression stocking system and method
Imaging apparatus and method of calculating usable time of imaging apparatus