Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Anti-proliferation domain of a human Bcl-2 and DNA encoding the same










Image Number 5 for United States Patent #5821082.

A domain of Bcl-2 that suppresses apoptosis by allowing cell survival permits cell proliferation when mutated. The wild type domain includes amino acid residues 51 to 97 (SEQ ID NO:13) of Bcl-2. Peptides including the domain and nucleotides encoding the domain are useful in molecular screening of human tumors for the presence of mutations that allow proliferation of cells that were otherwise marked for apoptosis. The peptides are also useful to screen for proteins that play a role in the modulation of cellular proliferation.








 
 
  Recently Added Patents
Device and method for controlling brightness of organic light emitting diode display
Dynamic data caches, decoders and decoding methods
Reconstruction of deforming surfaces by canceling ambient occlusion and refining 3-D shape
Resist underlayer film forming composition for lithography, containing aromatic fused ring-containing resin
Movable assemblies for an image reader unit and a cover unit in an image formation apparatus
Linked area parameter adjustment for spinal cord stimulation and associated systems and methods
Baseball player stationery tab
  Randomly Featured Patents
Toner container with biased closure
Data processing system
Method for mounting wall constituent members and a guide jig to be used in the same method
Method and system for sensing gas incorporating an integrated reference element
Optical system including provisions for correcting scanning beam spot displacements due to changing ambient conditions
Wireless communication system and method, and base station apparatus
Method and system for providing restricted access to a storage medium
Container
Interbody implant
Backrest assembly with chamber for articles