Resources Contact Us Home
Anti-proliferation domain of a human Bcl-2 and DNA encoding the same

Image Number 5 for United States Patent #5821082.

A domain of Bcl-2 that suppresses apoptosis by allowing cell survival permits cell proliferation when mutated. The wild type domain includes amino acid residues 51 to 97 (SEQ ID NO:13) of Bcl-2. Peptides including the domain and nucleotides encoding the domain are useful in molecular screening of human tumors for the presence of mutations that allow proliferation of cells that were otherwise marked for apoptosis. The peptides are also useful to screen for proteins that play a role in the modulation of cellular proliferation.

  Recently Added Patents
Method and system for electronic assistance in dispensing pharmaceuticals
Supplier capability methods, systems, and apparatuses for extended commerce
Dye-sensitized solar cell, dye-sensitized solar cell module, and coating liquid for forming electrolyte layer
Soybean cultivar CL1013675
Fire detector
Electrical converter with variable capacitor
Knife grip
  Randomly Featured Patents
Slide switch
Cataract extraction apparatus and method with rapid pulse phaco power
Compact size electromechanical translation apparatus
Exciter-excitation system and methods for communications
Blockwise coding process, of MPEG type, in which a resolution is assigned to each block
Thermoplastic resin composition, production thereof, and molded article thereof
Wireless LAN with dynamic channel selection
Display system