Resources Contact Us Home
Anti-proliferation domain of a human Bcl-2 and DNA encoding the same

Image Number 5 for United States Patent #5821082.

A domain of Bcl-2 that suppresses apoptosis by allowing cell survival permits cell proliferation when mutated. The wild type domain includes amino acid residues 51 to 97 (SEQ ID NO:13) of Bcl-2. Peptides including the domain and nucleotides encoding the domain are useful in molecular screening of human tumors for the presence of mutations that allow proliferation of cells that were otherwise marked for apoptosis. The peptides are also useful to screen for proteins that play a role in the modulation of cellular proliferation.

  Recently Added Patents
Performing a cyclic redundancy checksum operation responsive to a user-level instruction
Three-term predictive adder and/or subtracter
Myoglobin blooming agents, films, packages and methods for packaging
Precision geolocation of moving or fixed transmitters using multiple observers
Variety corn line LIC7382
Ni-, Co-, and Mn- multi-element doped positive electrode material for lithium battery and its preparation method
Anti-slip strip for vehicle running boards
  Randomly Featured Patents
Centralized biometric authentication
Lubricants for reciprocating air compressors
Method of driving electroluminescent device
Disubstituted triphenylmethylmidazoles for treating mycotic infections
Method and equipment for plotting section images of objects subjected to ultrasonic examination
Recording device having detection means for detecting additional information in reception data and for recording the additional information in a positionally fixed area in a recording track
Electro-optical apparatus utilizing at least three electro-optical modulating device to provide a sythesized color image and method of driving same
Third party VPN certification
Charging device for electrophotographic equipment