Resources Contact Us Home
Anti-proliferation domain of a human Bcl-2 and DNA encoding the same

Image Number 5 for United States Patent #5821082.

A domain of Bcl-2 that suppresses apoptosis by allowing cell survival permits cell proliferation when mutated. The wild type domain includes amino acid residues 51 to 97 (SEQ ID NO:13) of Bcl-2. Peptides including the domain and nucleotides encoding the domain are useful in molecular screening of human tumors for the presence of mutations that allow proliferation of cells that were otherwise marked for apoptosis. The peptides are also useful to screen for proteins that play a role in the modulation of cellular proliferation.

  Recently Added Patents
Insulated container sleeve
Liquid crystal display
Case for a tablet computer
Light receiving element with offset absorbing layer
Processing circuitry for use with a position sensor
Charging seat having cleaning member
People engine optimization
  Randomly Featured Patents
Bluetooth.TM. hands-free kit structure
Method of forming a corespun yarn for fire resistant safety apparel
Tetrazolium compounds for cell viability assays
Computer generated representation of the imaging pattern of an imaging device
Angled pool cleaner
Method for producing a T-stringer
Organotin miticidal and insecticidal compounds
Electronic circuit for DC conversion of fluorescent lighting ballast
Magnetic card reader caddy
High luminance polarizing plate, and liquid crystal panel and image display using same