Resources Contact Us Home
Anti-proliferation domain of a human Bcl-2 and DNA encoding the same

Image Number 5 for United States Patent #5821082.

A domain of Bcl-2 that suppresses apoptosis by allowing cell survival permits cell proliferation when mutated. The wild type domain includes amino acid residues 51 to 97 (SEQ ID NO:13) of Bcl-2. Peptides including the domain and nucleotides encoding the domain are useful in molecular screening of human tumors for the presence of mutations that allow proliferation of cells that were otherwise marked for apoptosis. The peptides are also useful to screen for proteins that play a role in the modulation of cellular proliferation.

  Recently Added Patents
Edge alphas for image translation
Efficiently emulating computer architecture condition code settings without executing branch instructions
Translucent internal graphics enhancement
Collaborative computing community role mapping system and method
Method for treating hyperglycemia
Computer program and apparatus for evaluating signal propagation delays
Driving system of display panel having a circuit of a voltage generator and driving method thereof
  Randomly Featured Patents
Rotary lawn mower
Method for setting free-state diameter of metal ring
Actinoplanes transformation process anti-hypertensive compound and method of use thereas
Gallium nitride based compound semiconductor laser and method of forming the same
Box with retractable lid for cosmetic or toiletry products
Stop watch
Semiconductor memory device and driving method thereof
Skinned hollow fiber membrane and method of manufacture
Method for receiving a radio frequency (RF) signal and RF receiver
IC memory card having masking function for preventing writing of data into a fixed memory area