Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Method for inducing death of neoplastic cells using piperazne derivatives










Image Number 12 for United States Patent #5733911.

A method for inducing cell death in neoplastic cells, includes the step of administering a compound of formula I or a pharmaceutically acceptable salt thereof, as a primary chemotherapeutic agent or substantially contemporaneously with chemotherapy, to a patient having multidrug-resistant neoplastic cells, in an amount sufficient to induce cell death in the neoplastic cells: ##STR1## where R.sup.1 is hydroxyl, C1-4 alkoxyl, C1-4 alkylcarboxyloxymethoxyl, phenyl C1-2 alkylamino group, 2,5-pyrrolidinedione-1-alkoxyl (C1-4), or ##STR2## wherein X.sup.1 is a chemical bond or C1-2 alkylene, X.sup.2 is hydrogen or carboxyl forming a 5-membered ring with X.sup.1 when X.sup.2 is methylene, X.sup.3 is hydrogen or C1-2 alkyl, X.sup.4 is hydrogen or C1-2 alkyl, or X.sup.3 and X.sup.4 together form a 5-membered ring, in which at least one of X.sup.2, X.sup.3, and X.sup.4 is hydrogen,R.sup.2 is C3-4 alkyl, R.sup.3 is C1-4 alkyl, ##STR3## in which n is an integer of 0 to 3.








 
 
  Recently Added Patents
Device to facilitate moving an electrical cable of an electric vehicle charging station and method of providing the same
Manufacturing method power semiconductor device
Method, apparatus, and manufacture for adaptation of video encoder tuning parameters
Probe for ultrasound diagnostic apparatus
High-performance AHCI interface
Protein purification
Selecting a converter operating mode of a PA envelope power supply
  Randomly Featured Patents
Multi-part sets of sheet material
Signal processing apparatus and method
Steering apparatus for vehicle
Gas bag module
Leaf spring adjustment kit
Position sensing and signaling system
Metal sheet piling
Nitrogen containing dispersant-viscosity improvers
Pneumatic radial tires including a tire component containing groups of reinforcing elements
Fishers counterbalance jig with stinger grip