Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Method for inducing death of neoplastic cells using piperazne derivatives










Image Number 12 for United States Patent #5733911.

A method for inducing cell death in neoplastic cells, includes the step of administering a compound of formula I or a pharmaceutically acceptable salt thereof, as a primary chemotherapeutic agent or substantially contemporaneously with chemotherapy, to a patient having multidrug-resistant neoplastic cells, in an amount sufficient to induce cell death in the neoplastic cells: ##STR1## where R.sup.1 is hydroxyl, C1-4 alkoxyl, C1-4 alkylcarboxyloxymethoxyl, phenyl C1-2 alkylamino group, 2,5-pyrrolidinedione-1-alkoxyl (C1-4), or ##STR2## wherein X.sup.1 is a chemical bond or C1-2 alkylene, X.sup.2 is hydrogen or carboxyl forming a 5-membered ring with X.sup.1 when X.sup.2 is methylene, X.sup.3 is hydrogen or C1-2 alkyl, X.sup.4 is hydrogen or C1-2 alkyl, or X.sup.3 and X.sup.4 together form a 5-membered ring, in which at least one of X.sup.2, X.sup.3, and X.sup.4 is hydrogen,R.sup.2 is C3-4 alkyl, R.sup.3 is C1-4 alkyl, ##STR3## in which n is an integer of 0 to 3.








 
 
  Recently Added Patents
System, method, and software for researching, analyzing and comparing expert witnesses
Electronic badge
Nonvolatile semiconductor memory device
Method for providing information of access point selection
IR(voltage) drop analysis in integrated circuit timing
Polymers
Display screen of a mobile terminal or portion thereof with a graphical user interface
  Randomly Featured Patents
Pressure reinforced plastic container having a moveable pressure panel and related method of processing a plastic container
Method and apparatus for processing messages
Method and apparatus for entering information into a portable electronic device
Faucet set
Method and apparatus for image forming using an ink-jet printing system
Method and apparatus for automatically applying and releasing automotive type parking brakes
Vehicle door comprising a panel attached directly to the structure of the door
Method and apparatus for updating flash memory resident firmware through a standard disk drive interface
Fire protection for wood shingle roof
Injection mold having interchangeable inscription plates