Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Identification of random nucleic acid sequence aberrations using dual capture probes which hybridize to different chromosome regions










Image Number 8 for United States Patent #5731153.

A method is provided for detecting nucleic acid sequence aberrations using two immobilization steps. According to the method, a nucleic acid sequence aberration is detected by detecting nucleic acid sequences having both a first nucleic acid sequence type (e.g., from a first chromosome) and a second nucleic acid sequence type (e.g., from a second chromosome), the presence of the first and the second nucleic acid sequence type on the same nucleic acid sequence indicating the presence of a nucleic acid sequence aberration. In the method, immobilization of a first hybridization probe is used to isolate a first set of nucleic acids in the sample which contain the first nucleic acid sequence type. Immobilization of a second hybridization probe is then used to isolate a second set of nucleic acids from within the first set of nucleic acids which contain the second nucleic acid sequence type. The second set of nucleic acids are then detected, their presence indicating the presence of a nucleic acid sequence aberration.








 
 
  Recently Added Patents
Method for forming contact hole
Apparatus and method for an iterative cryptographic block
System and method for routing streaming data requests
Reducing voltage stress in a flyback converter design
Method and system for expanding axial coverage in iterative reconstruction in computer tomography (CT)
Multi-channel memory system including error correction decoder architecture with efficient area utilization
Engineered magnetic layer with improved perpendicular anisotropy using glassing agents for spintronic applications
  Randomly Featured Patents
Clip for heat sink
Processes for the production of glass article
Color-plus-clear composite coating composition containing tin catalysts
Method for sealing an opening
Self-monitoring latch pin lock for folding wing aircraft
Installation for controlling the sealed condition of water-gas heat exchangers for industrial furnaces
Memorandum sheet dispenser
Multi-band vertical antenna
Organic conversion system
Safe, rechargeable, battery-containing power pack and method