Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Identification of random nucleic acid sequence aberrations using dual capture probes which hybridize to different chromosome regions










Image Number 8 for United States Patent #5731153.

A method is provided for detecting nucleic acid sequence aberrations using two immobilization steps. According to the method, a nucleic acid sequence aberration is detected by detecting nucleic acid sequences having both a first nucleic acid sequence type (e.g., from a first chromosome) and a second nucleic acid sequence type (e.g., from a second chromosome), the presence of the first and the second nucleic acid sequence type on the same nucleic acid sequence indicating the presence of a nucleic acid sequence aberration. In the method, immobilization of a first hybridization probe is used to isolate a first set of nucleic acids in the sample which contain the first nucleic acid sequence type. Immobilization of a second hybridization probe is then used to isolate a second set of nucleic acids from within the first set of nucleic acids which contain the second nucleic acid sequence type. The second set of nucleic acids are then detected, their presence indicating the presence of a nucleic acid sequence aberration.








 
 
  Recently Added Patents
Rear bumper for an automobile
Image processing apparatus, control method for the same, and storage medium
Encoding method and encoding device, decoding method and decoding device and transcoding method and transcoder for multi-object audio signals
Method for superconducting connection between MgB2 superconducting wires via a MgB2 matrix made from a boron powder compressed element infiltrated with Mg
Method and system for processing dictated information
Vehicle-mounted camera stabilized passively by vibration isolators
Method for execution upon processing of at least one histological sample
  Randomly Featured Patents
Score board for golf cart
Apparatus and method for examining and standardizing line connections
Transaction card sheet product and method of making same
Fuse
Keratoconjunctivitis sicca therapy
Valveless revolving cylinder engine
Quantitative opaque particle agglutination assay
Color images formed by multiple diffraction gratings
Wireless energy transfer with feedback control for lighting applications
Door closer having means to neutralize the door closing force exerted thereby