Resources Contact Us Home
Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers

Image Number 9 for United States Patent #5626863.

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.

  Recently Added Patents
Position pointer, variable capacitor and inputting apparatus
Selenium/group 3A ink and methods of making and using same
Push button
Linerless labels
Pressure-sensitive adhesive composition for optical films, pressure-sensitive adhesive optical film and image display
Heterocyclic compounds as CCR2B antagonists
  Randomly Featured Patents
Gearmotor for the alternate drive of two operations
Synthetic sponge-type articles having excellent water retention
Systematic equipments for recycling raw materials from waste wires
Analog signal processing circuit photo detector and image forming apparatus
Modular computer device and computer keyboard for modular device
Digital high definition television receiver with features that facilitate trick-play modes on a digital VCR
Automated storage library brush failure detection
Fingerprint controlled public key cryptographic system
Position detector for rotary element such as an internal combustion engine crankshaft or the like
Breathing assistance apparatus