Resources Contact Us Home
Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers

Image Number 15 for United States Patent #5626863.

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.

  Recently Added Patents
Optical channel transport unit frames transmission having interleaved parity
Stabilized redispersible polymer powder compositions
Method for drug screening and characterization by calcium flux
Methods of enhancing diabetes resolution
Transparent conductive structure
Method and system for simulating superimposition of a non-linearly stretchable object upon a base object using representative images
Electrical connector
  Randomly Featured Patents
Process of making a unified pressure-sensitive adhesive tape
Anti-invasive and anti-angiogenic compositions and methods
Tone signal generation device with resonance tone effect
Reinforcement supports
Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus
Method of producing surface acoustic wave device and the surface acoustic wave device
Tire tread
Memory system having a plurality of serially connected devices
Monolithic group III-V power converter
Automotive exhaust component and method of manufacture