Resources Contact Us Home
Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers

Image Number 15 for United States Patent #5626863.

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.

  Recently Added Patents
Compression molding method and reinforced thermoplastic parts molded thereby
Apparatus and method for image reconstruction and CT system
Method and system for producing fluoride gas and fluorine-doped glass or ceramics
Wire guide
Method and apparatus for triggering expiration of a data tag device
Fast port switching in an audiovisual receiver by use of port pre-authentication by a partial PHY decoder core
Image forming apparatus, image forming method, and computer readable medium for identifying target-recording element using detection pattern
  Randomly Featured Patents
Transparent double-injection field-effect transistor
Fluid mill powered vehicle
Pharmaceutical compositions and methods
Differential device
Low cost, low pressure, feedback passage-free fluidic oscillator with interconnect
Compiling and accessing subject-specific information from a computer network
Apparatus and method for carrying skis and ski poles
Device for sample preparation
Heat transport system
Reference voltage based equivalent series resistance (ESR) emulation for constant on-time (COT) control of buck regulators