Resources Contact Us Home
Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers

Image Number 15 for United States Patent #5626863.

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.

  Recently Added Patents
Semiconductor device and method of manufacturing the same
Data recording apparatus with recording control based on defect block and control method thereof
Inflatable workshop
Display control device, display control method, and touchpad input system
System and method for optimizing utilization of inventory space for dispensable articles
Correlating trace data streams
  Randomly Featured Patents
Photographic film assemblage
Gear dependent manual modulation transmission control strategy
High solubility K.sub.2 SO/KNO.sub.4 conpositions
Method of and apparatus for shredding a web of plastic film
Lawn edging
Agent delivery catheter having an inflation bridge between two axially spaced balloons
Cloning and sequencing of allergens of dermatophagoides house dust mite
Solder mask resins having improved stability containing a multifunctional epoxide and a partial ester or styrene-maleic anhydride copolymer
Dual plate antenna
Windowed fire door