Resources Contact Us Home
Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers

Image Number 14 for United States Patent #5626863.

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.

  Recently Added Patents
Electric discharge machining hole drilling
Tracking data eye operating margin for steady state adaptation
Controlling ring-back tone output prior to a communication connection in mobile terminal
Process of preparing functionalized polymers via enzymatic catalysis
Performance apparatus and electronic musical instrument
Puncture resistant fabric
Output queued switch with a parallel shared memory, and method of operating same
  Randomly Featured Patents
Nuclear fuel conversion systems
Body-insertable apparatus with power supply control
Hydraulic actuator in automatic transmission
Phenolic benzothiazole derivatives and their use as corrosion inhibitors
Segmented document transport section having accelerated take-away belts
Alginate-bioactive agent conjugates
Apparatus having an electromagnetic actuator including an armature and at least one inductive element connected to the armature for determining the position of the armature
Method and apparatus for performing wake on LAN power management
Sheet feeding apparatus and image forming apparatus
Portable labeling machine