Resources Contact Us Home
Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers

Image Number 14 for United States Patent #5626863.

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.

  Recently Added Patents
Piperazinedione compounds
Multi-dimensional tuple support in rule engines
Modified continuous phase modulation communications system and related methods
Phone messaging using audio streams
Packaging article
Pixel structure of organic light emitting device
Hepatitis C virus inhibitors
  Randomly Featured Patents
Method and apparatus for controlling passenger flow on aircraft
Semiconductor memory device having an arrangement to reduce stresses on non-selected ferroelectric capacitors while achieving high integration
Tubular plastics material net having corrugations
Vehicle braking force control device and control method of the same
Flexible and/or laterally stable foot-support structures and products containing such support structures
Fire hydrant
Semiconductor device, memory system, and electronic instrument
Rotary wheel-end assembly for tire inflation system
Light fixture
Washing apparatus for printing press cylinders having a spring-band freewheel tensioning device