Resources Contact Us Home
Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers

Image Number 14 for United States Patent #5626863.

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hydrophilic core itself may be degradable, thus combining the core and extension functions. Macromers are polymerized using free radical initiators under the influence of long wavelength ultraviolet light, visible light excitation or thermal energy. Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. Preferred applications for the hydrogels include prevention of adhesion formation after surgical procedures, controlled release of drugs and other bioactive species, temporary protection or separation of tissue surfaces, adhering of sealing tissues together, and preventing the attachment of cells to tissue surfaces.

  Recently Added Patents
Specimen preparation device, and control method in specimen preparation device
Extension of physical downlink control channel coverage
Liquid low temperature injection molding process
Electronic system with vertical intermetallic compound
Liquid crystal display apparatus
Profile-based user access to a network management system
Method for fabricating solar cell
  Randomly Featured Patents
Ozonated water flow and concentration control apparatus
Supported bioprosthetic heart valve with compliant orifice ring
Jewel case packaging system for recording media
Solenoid actuated valve with a damping device
Computerized system and method for teaching and assessing the holistic scoring of open-ended questions
Security system
Apparatus and method for ex-situ testing of performance parameters on an electrostatic chuck
Self locking nut for fuel assembly tie rods
Drive control apparatus for hybrid vehicle