Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Hybrid immunoglobulin-thrombolytic enzyme molecules which specifically bind a thrombus, and methods of their production and use










Image Number 12 for United States Patent #5609869.

Hybrid immunoglobulin-enzyme molecules are provided which are composed of antibodies, or derivatives or fragments thereof, which specifically bind an arterial or venous thrombus that are operably linked to the enzymatically active portions of thrombolytic enzymes such as plasminogen activators. In a preferred embodiment the hybrid molecules specifically bind to fibrin and have fibrinolytic activity. The hybrid molecules of the present invention may be produced by any means, including chemical conjugation, or by means of recombinant DNA, genetic engineering and/or hybridoma technology. Methods for making and using the molecules in diagnosis and therapy are also disclosed.








 
 
  Recently Added Patents
Potential separation for filling level radar
Preparation of isomerically pure substituted cyclohexanols
Electrophotographic photoreceptor and image forming apparatus including the same
Method and system for filtering noises in an image scanned by charged particles
Phosphonate compounds
Verification of a portable consumer device in an offline environment
Voltage detector having voltage detection printed board
  Randomly Featured Patents
Ratchetable open-ended wrench
Projectile slide-pushers for cross bows
Motion converter for converting rotation into to-and-fro displacement
Process for preparing carboxylates of alkylpolyoxyalkylenes
Ultrasonic process and apparatus for monitoring and measuring the evolution with time of physico-chemical, biological or bacteriological phenomena
Portable electronic device with a security function and a nonvolatile memory
Associative memory circuit and TLB circuit
Multidimensional data display apparatus, method, and multidimensional data display program
Sensing configuration in carrier aggregation scenarios
Method and apparatus for providing configurable layers and protocols in a communications system