Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Hybrid immunoglobulin-thrombolytic enzyme molecules which specifically bind a thrombus, and methods of their production and use










Image Number 12 for United States Patent #5609869.

Hybrid immunoglobulin-enzyme molecules are provided which are composed of antibodies, or derivatives or fragments thereof, which specifically bind an arterial or venous thrombus that are operably linked to the enzymatically active portions of thrombolytic enzymes such as plasminogen activators. In a preferred embodiment the hybrid molecules specifically bind to fibrin and have fibrinolytic activity. The hybrid molecules of the present invention may be produced by any means, including chemical conjugation, or by means of recombinant DNA, genetic engineering and/or hybridoma technology. Methods for making and using the molecules in diagnosis and therapy are also disclosed.








 
 
  Recently Added Patents
Fault diagnosis based on design partitioning
Adjustable bracelet
Lateral displacement and rotational displacement sensor
Method and system for providing spin transfer based logic devices
Electronic device
Line-based compression for digital image data
System and method for replenishing quantities of trading orders
  Randomly Featured Patents
Drill press
Control system provided with power supply unit operating based on operation modes including standby mode
Anatomically shaped air-mattress
Ring oscillator devices and methods of generating signals
Random access control method and optical disc driver
Two-door, locked mailbox
Resist composition and patterning process
Apparatus for transporting developed disc films in copying machines
Polishing apparatus including attitude controller for dressing apparatus
Integrated circuits with nonvolatile memory elements