Resources Contact Us Home
Tumor suppressor gene

Image Number 5 for United States Patent #5556945.

A detailed genetic map on human chromosome 11 was prepared. Then, a commonly deleted region on the chromosome in the tumor tissues of patients with multiple endocrine neoplasia type 1 was identified. Further, by linkage analysis on a family line with this disease, a gene causative of this disease was localized. A gene present in the region common to these observations was cloned and the structure of this gene was determined. Because a protein coded by this DNA is homologous with those of transcriptional factors, it is expected that the above-mentioned gene may be a novel tumor suppressor gene. Further, it is also expected that the above-mentioned gene and a protein coded for thereby may be useful in preparation of a remedy for cancer and a diagnostic drug for cancer.

  Recently Added Patents
Managing device functionality during predetermined conditions
Attribute category enhanced search
Movable assemblies for an image reader unit and a cover unit in an image formation apparatus
Ejection station
Parallel power inverter motor drive system
Method of operating a split gate flash memory cell with coupling gate
Nucleic acid sequences encoding strictosidine synthase proteins
  Randomly Featured Patents
Anti-platelet membrane glycoprotein VI monoclonal antibody
Oligomerization of alpha olefins using metallocene-SSA catalyst systems and use of the resultant polyalphaolefins to prepare lubricant blends
Microscope with a focusing assist apparatus
Driver handle
Plastics recovery system
Approach for securely printing electronic documents
Outdoor lantern
Compensation circuit for display contrast voltage control
Non-gangable box with embossed sides
Antibacterial compounds, processes for their preparation and compositions containing them