Resources Contact Us Home
Biodegradable bursting release system

Image Number 4 for United States Patent #5429822.

A biodegradable polymeric multiphasic release system of one or more biodegradable bursting units capable of delivering biologically active substances in a burst or pulse at predetermined times and a method for constructing those units is disclosed. The individual bursting units of the system may take the form of a biodegradable, membrane coated capsule surrounding a core material which may include an active agent. The membrane ruptures after a predetermined time upon exposure to water or bodily, or other aqueous environmental fluids. The bursting units may be used in any situation in which a controlled pulsed release of an active substance is desired. The predetermined time release of each bursting unit is controlled by the composition of the core material, the initial radius and wall thickness of the membrane and the porosity of the membrane. The core material may also contain a chemical composition which generates gas as fluid is drawn into the bursting unit thus adding an additional design variable for predetermining bursts.

  Recently Added Patents
Selecting content for storage in a multi-device cache
Resuming piecewise calibration of a real-time-clock unit after a measured offset that begins at the next calibration period
Wireless device with extendable antenna
Manufacturing process for cellular screening substratum, resultant substratum, and method and apparatus for screening
Optical packet signal transmission device and WDM optical communication network
Therapeutic human anti-IL-1R1 monoclonal antibody
Universal tablet and smartphone holder
  Randomly Featured Patents
Cap assembly with friction drag on tension brush
Procedure for the sex determination of embryos in mammals especially applied to bovine embryos
System for calculating formation temperatures
Method of manufacturing a ball
Memory cell with a vertically oriented transistor coupled to a digit line and method of forming the same
Holding clips for stakes supporting metal concrete forms
Mechanism for sharing web-based imaging information from a mainframe computing environment
Method and apparatus for high performance branching in pipelined microsystems
Dense content addressable memory cell
Method for determining the degree of change of material properties of underground strata